The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Melatonin therapy for REM sleep behavior disorder: a critical review of evidence
Open accessAbstract
REM sleep behavior disorder (RBD) is a parasomnia associated with dream enactment often involving violent or potentially injurious behaviors during REM sleep that is strongly associated with synucleinopathy neurodegeneration. Clonazepam has long been suggested as the first-line treatment option for RBD. However, evidence supporting melatonin therapy is expanding. Melatonin appears to be beneficial for the management of RBD with reductions in clinical behavioral outcomes and decrease in muscle tonicity during REM sleep. Melatonin also has a favorable safety and tolerability profile over clonazepam with limited potential for drug-drug interactions, an important consideration especially in elderly individuals with RBD receiving polypharmacy. Prospective clinical trials are necessary to establish evidence-basis for melatonin and clonazepam as RBD therapies.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The American Geriatrics Society 2012 Beers Criteria Update Expert Panel (2012) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2012.03923.x · Cited by 2,578
Lyketsos, C. G., Lopez, O., Jones, B., Fitzpatrick, A. L., Breitner, J., & DeKosky, S. (2002) · JAMA · doi:10.1001/jama.288.12.1475 · Cited by 2,049
Brzezinski, A. (1997) · New England Journal of Medicine · doi:10.1056/nejm199701163360306 · Cited by 1,549
Boeve, B. F., Silber, M. H., Ferman, T. J., Lin, S. C., Benarroch, E. E., Schmeichel, A. M., Ahlskog, J. E., Caselli, R. J., Jacobson, S., Sabbagh, M., et al. (2013) · Sleep Medicine · doi:10.1016/j.sleep.2012.10.015 · Cited by 393
Self-citationA polysomnographic and clinical report on sleep-related injury in 100 adult patients
(1989) · American Journal of Psychiatry · doi:10.1176/ajp.146.9.1166 · Cited by 354
Parasomnias: An Updated Review
Howell, M. J. (2012) · Neurotherapeutics · doi:10.1007/s13311-012-0143-8 · Cited by 165
Cited by
A review of sleep disorders and melatonin
Xie, Z., Chen, F., Li, W. A., Geng, X., Li, C., Meng, X., Feng, Y., Liu, W., & Yu, F. (2017) · Neurological Research · doi:10.1080/01616412.2017.1315864 · Cited by 406
New evidence on the management of Lewy body dementia
Taylor, J.-P., McKeith, I. G., Burn, D. J., Boeve, B. F., Weintraub, D., Bamford, C., Allan, L. M., Thomas, A. J., & O'Brien, J. T. (2020) · The Lancet Neurology · doi:10.1016/s1474-4422(19)30153-x · Cited by 347
Self-citationSleep Disturbances in Frontotemporal Dementia
McCarter, S. J., St. Louis, E. K., & Boeve, B. F. (2016) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-016-0680-3 · Cited by 80
Self-citationSleep in Neurodegenerative Disorders
Malkani, R., & Attarian, H. (2015) · Current Sleep Medicine Reports · doi:10.1007/s40675-015-0016-x · Cited by 12
Metadata
- Authors
- McGrane, I. R., Leung, J. G., St. Louis, E. K., & Boeve, B. F.
- Venue
- Sleep Medicine
- Publisher
- Elsevier BV
- Published
- 2015-01
- Volume
- 16
- Issue
- 1
- Pages
- 19-26
- ISSN
- 1389-9457 (ISSN-L)
- OpenAlex
- W2131638502
- Cited by
- 183
- References
- 6
- FWCI
- 15.97
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Melatonin therapy for REM sleep behavior disorder: a critical review of evidence. https://app.cochat.ai/papers/10.1016/j.sleep.2014.09.011
- The paper
- McGrane, I. R., Leung, J. G., St. Louis, E. K., & Boeve, B. F. (2015). Melatonin therapy for REM sleep behavior disorder: a critical review of evidence. Sleep Medicine. https://doi.org/10.1016/j.sleep.2014.09.011
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.