Prevalence of substance use disorder and psychiatric comorbidity burden among pregnant women with opioid use disorder in a large administrative database, 2009–2014
Open accessAbstract
OBJECTIVES: Using data from the Healthcare Cost and Utilization Project (HCUP), we estimated prevalence of individual substance use disorders (SUDs) and psychiatric comorbidities among pregnant women with opioid use disorder (OUD) in the New York State from 2009 to 2014. METHODS: In this cross-sectional study, pregnancy outcome and gestational age at delivery were estimated, and OUD diagnosis during pregnancy or at delivery discharge was identified. Prevalence of SUDs and psychiatric comorbidities were then calculated. RESULTS: Among 1,463,302 pregnant women, 8324 (0.57%) were diagnosed with OUD during pregnancy or at delivery. The most frequent SUDs or psychiatric comorbidities among pregnant women with OUD were non-opioid SUD (78.2%), followed by tobacco use disorder (74.9%), generalized anxiety disorder (38.0%), major depressive disorder (36.9%), cannabis use disorder (28.3%) and cocaine use disorder (27.4%). CONCLUSIONS: Most pregnant women with OUD were diagnosed with at least one non-opioid SUD and tobacco use disorder. Generalized anxiety disorder and major depressive disorder were also common, suggesting that mental health screenings should be prioritized for pregnant women with OUD.
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Women with opioid use disorder have high rates of co-occurring mental health conditions, with depression and anxiety conditions ranging as high as 65-75%.
“Women with OUD have high rates of co-occurring mental health conditions, with depression and anxiety conditions ranging as high as 65–75% [7–9].”
Roughly 78% of women with opioid use disorder are also diagnosed with at least one non-opioid substance use disorder.
“Additionally, roughly 78% of women with OUD are also diagnosed with at least one non-opioid substance use disorder [9].”
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Saavedra, L. M., Morgan-López, A. A., Hien, D. A., López-Castro, T., Ruglass, L. M., Back, S. E., Fitzpatrick, S., Norman, S. B., Killeen, T. K., Ebrahimi, C. T., et al. (2021) · Contemporary Clinical Trials · doi:10.1016/j.cct.2021.106479 · Cited by 31 · see citing works
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“Women with OUD have high rates of co-occurring mental health conditions, with depression and anxiety conditions ranging as high as 65–75% [7–9].”
- Authors
- Shen, Y., Lo-Ciganic, W.-H., Segal, R., & Goodin, A. J.
- Affiliations
- University of Florida (US)
- Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida
- Corresponding author
- Goodin, Amie J.
- Venue
- Journal of Psychosomatic Obstetrics & Gynecology
- Publisher
- Informa UK Limited
- Published
- 2020-02-18
- Volume
- 42
- Issue
- 3
- Pages
- 235-241
- ISSN
- 0167-482X (ISSN-L)
- 1743-8942
- OpenAlex
- W3007832732
- Cited by
- 38
- References
- 41
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 7 · 2023: 6 · 2022: 3 · 2021: 6 · 2020: 3
- FWCI
- 4.34
- Type
- journal article
- Language
- en
- Open access
- green
- figshare.com
- Licence
- cc-by
- Locations
- Journal of Psychosomatic Obstetrics & Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Figshare (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Figshare (cc-by)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Keywords
- opioid use disorder, pregnancy, substance use disorders, psychiatric comorbidity, tobacco use disorder, cannabis use disorder, cocaine dependence, generalized anxiety disorder, major depressive disorder, prevalence, mental health screening, New York State
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