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Determination of bisphenol A in canned vegetables and fruit by high performance liquid chromatography

Yoshida, Terumitsu, Horie, Masakazu, Hoshino, Youji, Nakazawa, Hiroyuki, Horie, Masakazu, Nakazawa, Hiroyuki·2001·Food Additives and Contaminants

Abstract

A high performance liquid chromatography (HPLC) method was developed for the determination of bisphenol A (BPA) that had migrated into canned fruit and vegetables. BPA was extracted with acetonitrile from the solid portion of canned food, and with an OASIS HLB cartridge from the aqueous portion, respectively. Both extracts were cleaned up on a Florisil cartridge. The HPLC separation was carried out on a Wakosil II 3C18 RS column (4.6 x 150 mm) with acetonitrile-water (40:60, v/v) as a mobile phase with a flow rate of 0.8 ml/min. BPA was detectable by UV detector at 228 nm and determined with the similarity of chromatographic peak spectrum by multiwavelength detector (similarity index was 0.99 or above). The quantification limits were 10 ng/g for the solid portion and 5 ng/ml for the aqueous portion, respectively. BPA was mainly detected in the solid portion of canned food and found at the maximum level of 11 micrograms per can. To verify migration into the solid portion of canned food, a partitioning experiment was carried out.

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Metadata

Authors
Yoshida, T., Horie, M., Hoshino, Y., Nakazawa, H., Horie, M., & Nakazawa, H.
Venue
Food Additives and Contaminants
Published
2001-01
Volume
18
Issue
1
Pages
69-75
ISSN
0265-203X (ISSN-L)
OpenAlex
W1970858934
Cited by
197
References
0
FWCI
8.34
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Determination of bisphenol A in canned vegetables and fruit by high performance liquid chromatography. https://app.cochat.ai/papers/10.1080/026520301446412
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Yoshida, T., Horie, M., Hoshino, Y., Nakazawa, H., Horie, M., & Nakazawa, H. (2001). Determination of bisphenol A in canned vegetables and fruit by high performance liquid chromatography. Food Additives and Contaminants. https://doi.org/10.1080/026520301446412

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