Parent bisphenol A accumulation in the human maternal-fetal-placental unit.
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BPA is detectable in maternal plasma in ranges from 0.3 to 18.9 ng/ml and in fetal plasma from 0 to 9.2 ng/ml.
“BPA is detectable in maternal and fetal plasma in ranges from 0.3 to 18.9 and 0 to 9.2 ng/ml respectively [2].”
From Gestational Exposure to Low Dose Bisphenol A Alters Social Behavior in Juvenile Mice (2011) · cites this paper as [2]
The 1.25 mg/kg BPA diet produces BPA exposure well within the range detected in human maternal blood (0.3 to 18.9 ng/ml).
“Thus this dose produces BPA exposure well within the range detected in human maternal blood, 0.3 to 18.9 ng/ml [2].”
From Gestational Exposure to Low Dose Bisphenol A Alters Social Behavior in Juvenile Mice (2011) · cites this paper as [2]
Cites
Exposure to bisphenol A advances puberty
Howdeshell, K. L., Hotchkiss, A. K., Thayer, K. A., Vandenbergh, J. G., & vom Saal, F. S. (1999) · Nature · doi:10.1038/44517 · Cited by 820 · cited 2× · see citing works
“Exposure of rodent fetuses to BPA at a very low dose (below the no-observed-adverse-effect level) typical of environmental exposure was found to produce postnatal estrogenic effects: reduced daily sperm production in males, increased prostate gland weight, alteration in the development and tissue organization of the m…”
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Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement
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The role of bisphenol A in shaping the brain, epigenome and behavior
Wolstenholme, J. T., Rissman, E. F., & Connelly, J. J. (2011) · Hormones and Behavior · doi:10.1016/j.yhbeh.2010.10.001 · Cited by 309 · see citing works
Transfer of bisphenol A across the human placenta
Balakrishnan, B., Henare, K., Thorstensen, E. B., Ponnampalam, A. P., & Mitchell, M. D. (2010) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2010.01.025 · Cited by 304 · see citing works
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Estrogen effects in allergy and asthma
Bonds, R. S., & Midoro-Horiuti, T. (2013) · Current Opinion in Allergy & Clinical Immunology · doi:10.1097/aci.0b013e32835a6dd6 · Cited by 208 · see citing works
Gestational Exposure to Low Dose Bisphenol A Alters Social Behavior in Juvenile Mice
Wolstenholme, J. T., Taylor, J. A., Shetty, S. R. J., Edwards, M., Connelly, J. J., & Rissman, E. F. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025448 · Cited by 168 · see citing works
“9 ng/ml [2].”
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Praegnatio Perturbatio—Impact of Endocrine-Disrupting Chemicals
Padmanabhan, V., Song, W., & Puttabyatappa, M. (2021) · Endocrine Reviews · doi:10.1210/endrev/bnaa035 · Cited by 103 · see citing works
Bisphenol A interferes with synaptic remodeling
Hajszan, T., & Leranth, C. (2010) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.06.004 · Cited by 101 · see citing works
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- Authors
- Schönfelder, G., Wittfoht, W., Hopp, H., Talsness, C. E., Paul, M., & Chahoud, I.
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2002-10-10
- Volume
- 110
- Issue
- 11
- Pages
- a703-a707
- ISSN
- 0091-6765 (ISSN-L)
- OpenAlex
- W4251734486
- Cited by
- 668
- References
- 1
- Citations by year
- 2026: 3 · 2025: 16 · 2024: 17 · 2023: 22 · 2022: 26 · 2021: 39 · 2020: 33 · 2019: 31 · 2018: 45 · 2017: 45 · 2016: 34 · 2015: 40 · 2014: 31 · 2013: 50 · 2012: 37
- FWCI
- 8.65
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Environmental Health Perspectives (publishedVersion)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Health, Environment, Cognitive Aging
- Keywords
- bisphenol A, maternal exposure, prenatal exposure, endocrine disruptors, placental transfer
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