The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Hyperthermia mediated liposomal drug delivery
Open accessAbstract
Drug delivery systems have been developed for cancer therapy in an attempt to increase the tumour drug concentration while limiting systemic exposure. Liposomes have achieved passive targeting of solid tumours through enhanced vascular permeability, which is greatly augmented by hyperthermia. However, anti-tumour efficacy has often been limited by slow release of bioavailable drug within the tumour. Local hyperthermia has become the most widely used stimulus for triggered release of liposomal drugs, through the use of specific lipids, polymers or other modifiers. A temperature-sensitive liposome containing doxorubicin has been shown to release 100% of contents through stabilized membrane pores within 10-20 s at 41 degrees C. This formulation has exhibited dramatic improvements in pre-clinical drug delivery and tumour regression and is now in clinical trials. Significantly, recent studies show that this liposome, in combination with local hyperthermia, exhibits vascular shutdown as a mechanism of anti-tumour effect that is not observed with free doxorubicin.
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Cites
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Cited by
Advances and Challenges of Liposome Assisted Drug Delivery
Sercombe, L., Veerati, T., Moheimani, F., Wu, S. Y., Sood, A. K., & Hua, S. (2015) · Frontiers in Pharmacology · doi:10.3389/fphar.2015.00286 · Cited by 2,632
Imaging and drug delivery using theranostic nanoparticles
Janib, S. M., Moses, A. S., & MacKay, J. A. (2010) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2010.08.004 · Cited by 1,248
Recent progress in tumor pH targeting nanotechnology
Lee, E. S., Gao, Z., & Bae, Y. H. (2008) · Journal of Controlled Release · doi:10.1016/j.jconrel.2008.05.003 · Cited by 866
Lipid-Based Drug Delivery Systems in Cancer Therapy: What Is Available and What Is Yet to Come
Yingchoncharoen, P., Kalinowski, D. S., & Richardson, D. R. (2016) · Pharmacological Reviews · doi:10.1124/pr.115.012070 · Cited by 744
Magnetic nanoparticle-based therapeutic agents for thermo-chemotherapy treatment of cancer
Hervault, A., & Thanh, N. T. K. (2014) · Nanoscale · doi:10.1039/c4nr03482a · Cited by 585
Metadata
- Authors
- Ponce, A. M., Vujaskovic, Z., Yuan, F., Needham, D., & Dewhirst, M. W.
- Venue
- International Journal of Hyperthermia
- Publisher
- Informa UK Limited
- Published
- 2006-01-01
- Volume
- 22
- Issue
- 3
- Pages
- 205-213
- ISSN
- 0265-6736 (ISSN-L)
- 1464-5157
- OpenAlex
- W2052412821
- Cited by
- 279
- References
- 28
- FWCI
- 12.19
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Ponce, A. M., Vujaskovic, Z., Yuan, F., Needham, D., & Dewhirst, M. W. (2006). Hyperthermia mediated liposomal drug delivery. International Journal of Hyperthermia. https://doi.org/10.1080/02656730600582956
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
