Impaired health-related quality of life and related risk factors among US adults with asthma
Open accessAbstract
OBJECTIVE: This study assessed health-related quality of life (HRQoL) and related risk factors among adults with asthma in the United States. Using the 2015 Behavioral Risk Factor Surveillance System (BRFSS), we examined the association between four domains of impaired HRQoL and selected explanatory factors. METHODS: A BRFSS sample of 39,321 adults with asthma was used in this study. We examined the association between fair/poor health, ≥ 14 mentally unhealthy days, ≥ 14 physically unhealthy days, and ≥ 14 days of activity limitation and selected explanatory variables (sex, race/ethnicity, age, annual household income, healthcare coverage, physical activity, smoking status, body mass index (BMI), having a coexisting disease, and being diagnosed with depression) using multivariable logistic regression models. RESULTS: Income, physical activity status, smoking status, coexisting diseases, and depression were strongly associated with all HRQoL domains. Blacks had significantly less ≥ 14 physically unhealthy days (23.4%; aPR = 0.82 [95% confidence interval (CI): 0.72, 0.92]) and ≥ 14 days of activity limitation (18.3%; aPR = 0.81 [0.70, 0.94]) and Hispanics had significantly more fair/poor health (38.4%; aPR = 1.31 [1.18, 1.45]) than whites. Underweight and obese had significantly more fair/poor health, and underweight significantly more ≥ 14 physically unhealthy days, compared with normal weight. Adults aged 55 years or older had significantly less ≥ 14 mentally unhealthy days than adults 18-24 years. CONCLUSIONS: Multiple factors were associated with impaired HRQoL. Providing strategies to address potential risk factors such as low income, physically inactive, smoker, and obese or underweight should be considered to improve HRQoL among adults with asthma.
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- Authors
- Pate, C. A., Zahran, H. S., & Bailey, C. M.
- Affiliations
- Centers for Disease Control and Prevention (US)
- Corresponding author
- Pate, Cynthia A.
- Venue
- Journal of Asthma
- Publisher
- Informa UK Limited
- Published
- 2018-05-11
- Volume
- 56
- Issue
- 4
- Pages
- 431-439
- ISSN
- 0277-0903 (ISSN-L)
- 1532-4303
- PMC
- PMC7202887
- OpenAlex
- W2801960800
- Cited by
- 23
- References
- 43
- Citations by year
- 2025: 4 · 2024: 4 · 2023: 2 · 2022: 5 · 2021: 2 · 2020: 1 · 2019: 4 · 2018: 1
- FWCI
- 1.37
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Asthma (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (CC999999)
- Topics
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Social Sciences › Health › Health disparities and outcomes
- Keywords
- asthma, health-related quality of life, risk factors, physical activity, smoking, body mass index, depression, activity limitation, mental health, racial and ethnic disparities, income
- MeSH terms
- Adult, Aged, Asthma, Ethnicity, Female, Humans, Male, Middle Aged, Quality of Life, Retrospective Studies, Risk Factors, Severity of Illness Index, Socioeconomic Factors, United States, Cohort Studies, Health Behavior, Exercise, Multivariate Analysis, Logistic Models, Databases, Factual, Anti-Asthmatic Agents, Disease Management
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