The DOI matches its Crossref record; 32 of the 33 references it cites were found in a registry or an index.
Psychedelic Microdosing: A Subreddit Analysis
Abstract
Self-administration of very low doses of psychedelic drugs to improve mental health and wellbeing and enhance cognitive function, known as microdosing, has received recent media attention, but little research has been conducted. We conducted a content analysis of discussions about microdosing from the online forum Reddit. We examined motivations, dosing practices, and perceived benefits and limitations of microdosing. Motivations included self-management of mental health issues, improvement of psychosocial wellbeing, and cognitive enhancement. Self-reported benefits included cognitive and creative enhancement, reduced depression and anxiety, enhanced self-insight and mindfulness, improved mood and attitude toward life, improved habits and health behaviors, and improved social interactions and interpersonal connections. Perceived limitations included issues related to dosing, adverse physical effects, taking illegal substances, limited or no mental health or cognitive improvement, increased anxiety, unpleasant "off" days, only short-term benefits, and concerns about dependence and drug-related risks. Standard doses of psychedelic drugs provided in therapeutic settings have potential as novel treatments for some mental health conditions, but clinical research is needed to understand if this is also the case for microdosing. In the meantime, harm reduction resources should be developed and made available to provide the best available information on the safer use of self-administered psychedelics.
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In the citing paper
“This reduction of top-down control facilitates increased levels of creativity through divergent thinking (Preller and V ollenweider 2018; Abraham et al. 2012), leading to novel problem-solving solutions and contributing to the recent rise in microdosing protocols among high-performing creative professionals (Lea et al. 2019; Polito and Stevenson 2019).”
From Cultural Evolution of Religion, Spirituality and Ritual: Impacts On Human Cooperation (2024) · cites this paper as Lea et al. 2019
In the citing paper
“Survey research has shown that some adults diagnosed with ADHD report using low, sub-hallucinogenic doses of psychedelic substances repeatedly, referred to as microdosing (MD), to self-treat their symptoms and as such to improve daily life functioning (4–7).”
From Trait mindfulness and personality characteristics in a microdosing ADHD sample: a naturalistic prospective survey study (2023) · cites this paper as [6]
In the citing paper
“Interestingly, enhanced levels of mindfulness have been reported after MD (6)”
From Trait mindfulness and personality characteristics in a microdosing ADHD sample: a naturalistic prospective survey study (2023) · cites this paper as [6]
In the citing paper
“The finding that mindfulness was enhanced in MD individuals is in line with previous studies reporting this association (6, 11), but in contrast to one previous prospective MD study that did not find any changes in mindfulness after 6 weeks of MD (13).”
From Trait mindfulness and personality characteristics in a microdosing ADHD sample: a naturalistic prospective survey study (2023) · cites this paper as [6]
Citations
Cites
Drug harms in the UK: a multicriteria decision analysis
Nutt, D. J., King, L. A., & Phillips, L. D. (2010) · The Lancet · doi:10.1016/s0140-6736(10)61462-6 · Cited by 1,681
Carhart-Harris, R. L., Leech, R., Hellyer, P. J., Shanahan, M., Feilding, A., Tagliazucchi, E., Chialvo, D. R., & Nutt, D. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00020 · Cited by 1,252
Psychedelics promote structural and functional neural plasticity
Ly, C., Greb, A. C., Cameron, L. P., Wong, J. M., Barragan, E. V., Wilson, P. C., Burbach, K. F., Soltanzadeh Zarandi, S., Sood, A., Paddy, M. R., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.05.022 · Cited by 1,207
Psilocybin with psychological support for treatment-resistant depression: six-month follow-up
Carhart-Harris, R. L., Bolstridge, M., Day, C. M. J., Rucker, J., Watts, R., Erritzoe, D. E., Kaelen, M., Giribaldi, B., Bloomfield, M., Pilling, S., et al. (2018) · Psychopharmacology · doi:10.1007/s00213-017-4771-x · Cited by 970
Malhi, G. S., Bassett, D., Boyce, P., Bryant, R., Fitzgerald, P. B., Fritz, K., Hopwood, M., Lyndon, B., Mulder, R., Murray, G., et al. (2015) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867415617657 · Cited by 842 · cited 2×
“recommended in clinical guidelines, although it is common for people to cease treatment without support (Malhi et al. 2015).”
BackgroundGasser, P., Holstein, D., Michel, Y., Doblin, R., Yazar-Klosinski, B., Passie, T., & Brenneisen, R. (2014) · Journal of Nervous & Mental Disease · doi:10.1097/nmd.0000000000000113 · Cited by 750
Leucht, S., Leucht, C., Huhn, M., Chaimani, A., Mavridis, D., Helfer, B., Samara, M., Rabaioli, M., Bächer, S., Cipriani, A., et al. (2017) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2017.16121358 · Cited by 542
Efficacy and effectiveness of antidepressants: current status of research
Pigott, H. E., Leventhal, A. M., Alter, G. S., & Boren, J. J. (2010) · Psychotherapy and Psychosomatics · doi:10.1159/000318293 · Cited by 347 · cited 1×
“Indeed, variable health outcomes from psychiatric medications have been well documented (Leucht et al. 2017; Pigott et al. 2010).”
BackgroundPotential Therapeutic Effects of Psilocybin
Johnson, M. W., & Griffiths, R. R. (2017) · Neurotherapeutics · doi:10.1007/s13311-017-0542-y · Cited by 328
A systematic study of microdosing psychedelics
Polito, V., & Stevenson, R. J. (2019) · PLoS ONE · doi:10.1371/journal.pone.0211023 · Cited by 235
Research works printed but not linked: 3
- 10.1016/j.biopsych.2019.1005.1019 · DOI
- Passie T., 2019, The science of microdosing psychedelics
- Waldman A., 2017, A really good day: How microdosing made a mega difference in my mood, my marriage, and my life
Cited by
Sorted by citations
Items 101–115 of 115
Investigación sobre microdosificación con hongos psilocibios: un artículo de reflexión
Duque, L. (2023) · Cultura y Droga · doi:10.17151/culdr.2023.28.35.3
“Éstas van desde la reducción de la ansiedad y la depresión, pasando por el mejoramiento del bienestar y el desempeño cognitivo, hasta el mejoramiento de la salud física y el aumento de la empatía, la espirtualidad y la curiosidad (Hutten et al. , 2019; Lea et al. , 2020).”
BackgroundInfluentialMicrodosing Psychedelics as a Promising New Pharmacotherapeutic
Kuypers, K. P. C. (2024) · Springer eBooks · doi:10.1007/978-3-031-61992-2_26
Totomanova, I., Haijen, E. C. H. M., Hurks, P. P. M., Ramaekers, J. G., & Kuypers, K. P. C. (2025) · International review of neurobiology · doi:10.1016/bs.irn.2025.03.002
Elbaz, S., Petracca, R., Argiropoulos, N., & Savard, Y. P. (2025) · Community Work & Family · doi:10.1080/13668803.2025.2561941
Murphy, R. J., Wardlaw, M., Smith, T., Noorani, T. N., Evans, W., Reynolds, L., Menkes, D. B., Sumner, R. L., & Muthukumaraswamy, S. D. (2025) · Journal of Humanistic Psychology · doi:10.1177/00221678251382624
Donegan, C. J., Daldegan‐Bueno, D., Sumner, R. L., Forsyth, A., Evans, W., Hoeh, N. R., Sundram, F., Menkes, D. B., Muthukumaraswamy, S. D., & Reynolds, L. (2025) · Therapeutic Advances in Psychopharmacology · doi:10.1177/20451253251396253
“16,17,21,22 Increased connection to nature and a broader sense of interconnectedness with the world have also been noted in previous anecdotal accounts, particularly among those with mental health conditions.”
InfluentialPsilocybin reporting in media (PRiMe) for the treatment of depression
Brar, G., Burke, T., Gribben, A. D., Harrington, C., Thuery, G., & Kelly, J. R. (2025) · Irish Journal of Psychological Medicine · doi:10.1017/ipm.2025.10142
“Lea and colleagues (Lea et al. 2020) similarly analysed psychedelic microdosing using Reddit.”
Wells, A., Muthukumaraswamy, A. P. S., Morunga, E., Evans, W., Cavadino, A., Bansal, M., Lawrence, N. J., Ashley, A., Hoeh, N. R., Sundram, F., et al. (2024) · Figshare · doi:10.6084/m9.figshare.25210532
Wells, A., Muthukumaraswamy, A. P. S., Morunga, E., Evans, W., Cavadino, A., Bansal, M., Lawrence, N. J., Ashley, A., Hoeh, N. R., Sundram, F., et al. (2024) · Figshare · doi:10.6084/m9.figshare.25210812
Daldegan‐Bueno, D., Donegan, C. J., Forsyth, A., Sumner, R. L., Murphy, R. J., Menkes, D. B., Evans, W. J., Hoeh, N. R., Sundram, F., Reynolds, L., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26942922
Daldegan‐Bueno, D., Donegan, C. J., Forsyth, A., Sumner, R. L., Murphy, R. J., Menkes, D. B., Evans, W. J., Hoeh, N. R., Sundram, F., Reynolds, L., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26827416
Murphy, R. J., Sumner, R. L., Evans, W. J., Menkes, D., Lambrecht, I., Ponton, R., Sundram, F., Hoeh, N. R., Ram, S., Reynolds, L., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14478492
Daldegan‐Bueno, D., Donegan, C. J., Forsyth, A., Sumner, R. L., Murphy, R. J., Menkes, D. B., Evans, W. J., Hoeh, N. R., Sundram, F., Reynolds, L., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26827380
Cellular mechanisms of serotonergic psychedelics - apical hypercontextualisation
Kaup, K., Jiménez, J. H., & Aru, J. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.106876
Exploratory Insights into 5-MeO-DMT Experiences on Reddit: A Thematic Analysis
Świeczkowski, D., Kwaśny, A., & Cubała, W. J. (2026) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2026.2727030
Metadata
- Authors
- Lea, T., Amada, N., & Jungaberle, H.
- Affiliations
- UNSW Sydney (AU)
- The Graduate Center, CUNY (US)
- MIND European Foundation for Psychedelic Science, Berlin, Germany
- Corresponding author
- Lea, Toby
- Venue
- Journal of Psychoactive Drugs
- Publisher
- Informa UK Limited
- Published
- 2019-10-24
- Volume
- 52
- Issue
- 2
- Pages
- 101-112
- ISSN
- 0279-1072 (ISSN-L)
- 2159-9777
- OpenAlex
- W2981686921
- Cited by
- 115
- References
- 33
- Citations by year
- 2026: 8 · 2025: 19 · 2024: 24 · 2023: 26 · 2022: 19 · 2021: 10 · 2020: 8 · 2019: 1
- FWCI
- 11.09
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Psychoactive Drugs (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Alexander von Humboldt-Stiftung (NA)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychedelics and Drug Studies
- Social Sciences › Arts and Humanities › Philosophy › Neuroethics, Human Enhancement, Biomedical Innovations
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Forensic Toxicology and Drug Analysis
- Keywords
- psychedelic microdosing, Reddit discussions, online forums, mental health self-management, cognitive enhancement, psychosocial well-being, anxiety and depression, harm reduction, drug addiction
- MeSH terms
- Self-Management, Psychosocial Functioning, Adult, Behavioral Symptoms, Cognition, Hallucinogens, Humans, Lysergic Acid Diethylamide, Psilocybin, Self Administration, Qualitative Research, Social Media
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