Strategies for healthy weight loss: from vitamin C to the glycemic response
Abstract
America is experiencing a major obesity epidemic. The ramifications of this epidemic are immense since obesity is associated with chronic metabolic abnormalities such as insulin resistance, dyslipidemia, and heart disease. Reduced physical activity and/or increased energy intakes are important factors in this epidemic. Additionally, a genetic susceptibility to obesity is associated with gene polymorphisms affecting biochemical pathways that regulate fat oxidation, energy expenditure, or energy intake. However, these pathways are also impacted by specific foods and nutrients. Vitamin C status is inversely related to body mass. Individuals with adequate vitamin C status oxidize 30% more fat during a moderate exercise bout than individuals with low vitamin C status; thus, vitamin C depleted individuals may be more resistant to fat mass loss. Food choices can impact post-meal satiety and hunger. High-protein foods promote postprandial thermogenesis and greater satiety as compared to high-carbohydrate, low-fat foods; thus, diet regimens high in protein foods may improve diet compliance and diet effectiveness. Vinegar and peanut ingestion can reduce the glycemic effect of a meal, a phenomenon that has been related to satiety and reduced food consumption. Thus, the effectiveness of regular exercise and a prudent diet for weight loss may be enhanced by attention to specific diet details.
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Background
- Authors
- Johnston, C. S.
- Affiliations
- Arizona State University (US)
- Corresponding author
- Johnston, Carol S.
- ORCID
- Johnston, Carol S.
- Venue
- Journal of the American College of Nutrition
- Publisher
- Informa UK Limited
- Published
- 2005-06
- Volume
- 24
- Issue
- 3
- Pages
- 158-165
- ISSN
- 0731-5724 (ISSN-L)
- 1541-1087
- OpenAlex
- W2000641507
- Cited by
- 73
- References
- 0
- Citations by year
- 2025: 3 · 2024: 2 · 2023: 2 · 2022: 3 · 2021: 4 · 2020: 2 · 2019: 4 · 2018: 3 · 2017: 2 · 2016: 4 · 2015: 3 · 2014: 5 · 2013: 1 · 2012: 7
- FWCI
- 0.47
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American College of Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Keywords
- weight loss, obesity, vitamin C, fat oxidation, glycemic response, satiety, postprandial thermogenesis, high-protein diet, vinegar, peanut ingestion, insulin resistance, energy expenditure, genetic polymorphism, dietary adherence
- MeSH terms
- Ascorbic Acid, Energy Metabolism, Health Promotion, Humans, Weight Loss, Glycemic Index
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