The DOI matches its Crossref record; 141 of the 141 references it cites were found in a registry or an index.
Natural and Modified (1→3)-β-D-Glucans in Health Promotion and Disease Alleviation
Abstract
A number of polysaccharides with beta-glycosidic linkage are widespread in nature in a variety of sources. All have a common structure and the (1-->3)-beta-D-glucan backbone is essential. They have attracted attention over the years because of their bioactive and medicinal properties. In many cases their functional role is a mystery, in others it is well established. Because of their insoluble chemical nature, particulate (1-->3)-beta-D-glucans are not suitable for many medical applications. Various methods of changing or modifying the beta-D-glucan chemical structure and transforming it to a soluble form have been published. The beta-D-glucan bioactive properties can be affected positively or negatively by such modifications. This review examines beta-glucan sources in nature, health effects and structure-activity relationships. It presents the current state of beta-D-glucan solubilization methods and discusses their effectiveness and application possibilities for the future.
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Cites
Collaborative Induction of Inflammatory Responses by Dectin-1 and Toll-like Receptor 2
Gantner, B. N., Simmons, R. M., Canavera, S. J., Akira, S., & Underhill, D. M. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20021787 · Cited by 1,643
Brown, G. D., & Gordon, S. (2001) · Nature · doi:10.1038/35092620 · Cited by 1,579
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens
Underhill, D. M., Ozinsky, A., Hajjar, A. M., Stevens, A., Wilson, C. B., Bassetti, M., & Aderem, A. (1999) · Nature · doi:10.1038/44605 · Cited by 1,368
Annals of the New York Academy of Sciences
R K, &. (1950) · The American Journal of the Medical Sciences · doi:10.1097/00000441-195006000-00023 · Cited by 1,124
Dectin-1 Is A Major β-Glucan Receptor On Macrophages
Brown, G. D., Taylor, P. R., Reid, D. M., Willment, J. A., Williams, D. L., Martinez-Pomares, L., Wong, S. Y. C., & Gordon, S. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20020470 · Cited by 1,014
Encyclopedia of plant physiology new series
(1980) · Comparative Biochemistry and Physiology Part A: Physiology · doi:10.1016/s0300-9629(80)80039-9 · Cited by 950
Bohn, J. A., & BeMiller, J. N. (1995) · Carbohydrate Polymers · doi:10.1016/0144-8617(95)00076-3 · Cited by 924
Biotechnology in the feed industry
Lyons, T. (1987) · Cited by 703
Chemistry and enzymology of marine algal polysaccharides
Percival, E. E., & McDowell, R. H. (1967) · Cited by 686
Novel and established applications of microbial polysaccharides
Sutherland, I. W. (1998) · Trends in Biotechnology · doi:10.1016/s0167-7799(97)01139-6 · Cited by 675
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Dawood, M. A. O., Koshio, S., & Esteban, M. Á. (2018) · Reviews in Aquaculture · doi:10.1111/raq.12209 · Cited by 921
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Dawood, M. A. O., & Koshio, S. (2016) · Aquaculture · doi:10.1016/j.aquaculture.2015.12.033 · Cited by 527
A critical review on production and industrial applications of beta-glucans
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Fernandes, A., Rodrigues, P. M., Pintado, M., & Tavaria, F. K. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.154824 · Cited by 264
β-Glucans in promoting health: Prevention against mutation and cancer
Mantovani, M. S., Bellini, M. F., Angeli, J. P. F., Oliveira, R. J., Silva, A. F., & Ribeiro, L. R. (2008) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2007.07.002 · Cited by 240
Metadata
- Authors
- Zeković, D. B., Kwiatkowski, S., Vrvić, M. M., Jakovljević, D., & Moran, C. A.
- Venue
- Critical Reviews in Biotechnology
- Publisher
- Informa UK Limited
- Published
- 2005-01
- Volume
- 25
- Issue
- 4
- Pages
- 205-230
- ISSN
- 0738-8551 (ISSN-L)
- 1549-7801
- OpenAlex
- W2164052164
- Cited by
- 309
- References
- 141
- FWCI
- 4.59
- Type
- journal article
- Language
- en
- Open access
- closed
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- Zeković, D. B., Kwiatkowski, S., Vrvić, M. M., Jakovljević, D., & Moran, C. A. (2005). Natural and Modified (1→3)-β-D-Glucans in Health Promotion and Disease Alleviation. Critical Reviews in Biotechnology. https://doi.org/10.1080/07388550500376166
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.