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Cited by 386

The DOI matches its Crossref record; 81 of the 81 references it cites were found in a registry or an index.

Pancreatic Cancer: A Review of Current Treatment and Novel Therapies

Open access
Kolbeinsson, Hordur Mar, Chandana, Sreenivasa, Wright, G. Paul, Chung, Mathew·2023·Journal of Investigative Surgery

Abstract

Pancreatic cancer is one of the leading causes for cancer-related deaths in the United States. Majority of patients present with unresectable or metastatic disease. For those that present with localized disease, a multidisciplinary approach is necessary to maximize survival and optimize outcomes. The quality and safety of surgery for pancreatic cancer have improved in recent years with increasing adoption of minimally invasive techniques and surgical adjuncts. Systemic chemotherapy has also evolved to impact survival. It is now increasingly being utilized in the neoadjuvant setting, often with concomitant radiation. Increased utilization of genomic testing in metastatic pancreatic cancer has led to better understanding of their biology, thereby allowing clinicians to consider potential targeted therapies. Similarly, targeted agents such as PARP inhibitors and immune checkpoint- inhibitors have emerged with promising results. In summary, pancreatic cancer remains a disease with poor long-term survival. However, recent developments have led to improved outcomes and have changed practice in the past decade. This review summarizes current practices in pancreatic cancer treatment and the milestones that brought us to where we are today, along with emerging therapies.

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Metadata

Authors
Kolbeinsson, H. M., Chandana, S., Wright, G. P., & Chung, M.
Venue
Journal of Investigative Surgery
Published
2022-10-03
Volume
36
Issue
1
Pages
2129884-2129884
ISSN
  • 0894-1939 (ISSN-L)
  • 1521-0553
OpenAlex
W4300716107
Cited by
386
References
81
FWCI
29.46
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Pancreatic Cancer: A Review of Current Treatment and Novel Therapies. https://app.cochat.ai/papers/10.1080/08941939.2022.2129884
The paper
Kolbeinsson, H. M., Chandana, S., Wright, G. P., & Chung, M. (2023). Pancreatic Cancer: A Review of Current Treatment and Novel Therapies. Journal of Investigative Surgery. https://doi.org/10.1080/08941939.2022.2129884

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.