Cancer statistics, 2019

Siegel, Rebecca L.; Miller, Kimberly D.; Jemal, Ahmedin

doi:10.3322/caac.21551

Cited by 20,160Global Cancer Incidence and ScreeningColorectal Cancer Screening and DetectionEconomic and Financial Impacts of Cancer

Cancer statistics, 2019

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Siegel, Rebecca L., Miller, Kimberly D., Jemal, Ahmedin·2019·CA: A Cancer Journal for Clinicians

DOI 10.3322/caac.21551

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Abstract

Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths that will occur in the United States and compiles the most recent data on cancer incidence, mortality, and survival. Incidence data, available through 2015, were collected by the Surveillance, Epidemiology, and End Results Program; the National Program of Cancer Registries; and the North American Association of Central Cancer Registries. Mortality data, available through 2016, were collected by the National Center for Health Statistics. In 2019, 1,762,450 new cancer cases and 606,880 cancer deaths are projected to occur in the United States. Over the past decade of data, the cancer incidence rate (2006‐2015) was stable in women and declined by approximately 2% per year in men, whereas the cancer death rate (2007‐2016) declined annually by 1.4% and 1.8%, respectively. The overall cancer death rate dropped continuously from 1991 to 2016 by a total of 27%, translating into approximately 2,629,200 fewer cancer deaths than would have been expected if death rates had remained at their peak. Although the racial gap in cancer mortality is slowly narrowing, socioeconomic inequalities are widening, with the most notable gaps for the most preventable cancers. For example, compared with the most affluent counties, mortality rates in the poorest counties were 2‐fold higher for cervical cancer and 40% higher for male lung and liver cancers during 2012‐2016. Some states are home to both the wealthiest and the poorest counties, suggesting the opportunity for more equitable dissemination of effective cancer prevention, early detection, and treatment strategies. A broader application of existing cancer control knowledge with an emphasis on disadvantaged groups would undoubtedly accelerate progress against cancer.

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The average lifetime risk of pancreatic cancer in the USA, about 1 in 64, is too low for population-based screening.
“The average lifetime risk of developing pancreatic cancer (~1 in 64 in the USA) is too low for population-based screening.”
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Deaths
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Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21660 · Cited by 108,699 · see citing works
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Cancer Statistics, 2021
Siegel, R. L., Miller, K. D., Fuchs, H. E., & Jemal, A. (2021) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21654 · Cited by 16,522 · see citing works
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Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable
CAMPBELL, K. L., WINTERS-STONE, K. M., WISKEMANN, J., MAY, A. M., SCHWARTZ, A. L., COURNEYA, K. S., ZUCKER, D. S., MATTHEWS, C. E., LIGIBEL, J. A., GERBER, L. H., et al. (2019) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002116 · Cited by 2,988 · see citing works
Comprehensive review of targeted therapy for colorectal cancer
Xie, Y.-H., Chen, Y.-X., & Fang, J.-Y. (2020) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-0116-z · Cited by 1,687 · see citing works
Estimated Projection of US Cancer Incidence and Death to 2040
Rahib, L., Wehner, M. R., Matrisian, L. M., & Nead, K. T. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.4708 · Cited by 1,339 · see citing works
Phase II open-label study of pembrolizumab in treatment-refractory, microsatellite instability–high/mismatch repair–deficient metastatic colorectal cancer: KEYNOTE-164
Le, D. T., Kim, T. W., Van Cutsem, E., Geva, R., Jäger, D., Hara, H., Burge, M., O’Neil, B., Kavan, P., Yoshino, T., et al. (2020) · Journal of Clinical Oncology · doi:10.1200/jco.19.02107 · Cited by 1,005 · see citing works
Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma
Gillette, M. A., Satpathy, S., Cao, S., Dhanasekaran, S. M., Vasaikar, S. V., Krug, K., Petralia, F., Li, Y., Liang, W.-W., Reva, B., et al. (2020) · Cell · doi:10.1016/j.cell.2020.06.013 · Cited by 820 · see citing works
Influence of the Gut Microbiome, Diet, and Environment on Risk of Colorectal Cancer
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The role of collagen in cancer: from bench to bedside
Xu, S., Xu, H., Wang, W., Li, S., Li, H., Li, T., Zhang, W., Yu, X., & Liu, L. (2019) · Journal of Translational Medicine · doi:10.1186/s12967-019-2058-1 · Cited by 735 · see citing works
Management of patients with increased risk for familial pancreatic cancer: updated recommendations from the International Cancer of the Pancreas Screening (CAPS) Consortium
Goggins, M., Overbeek, K. A., Brand, R., Syngal, S., Del Chiaro, M., Bartsch, D. K., Bassi, C., Carrato, A., Farrell, J., Fishman, E. K., et al. (2020) · Gut · doi:10.1136/gutjnl-2019-319352 · Cited by 659 · see citing works
Peptide-Based Vaccines: Current Progress and Future Challenges
Malonis, R. J., Lai, J. R., & Vergnolle, O. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00472 · Cited by 602 · see citing works
A rectal cancer organoid platform to study individual responses to chemoradiation
Ganesh, K., Wu, C., O’Rourke, K. P., Szeglin, B. C., Zheng, Y., Sauvé, C.-E. G., Adileh, M., Wasserman, I., Marco, M. R., Kim, A. S., et al. (2019) · Nature Medicine · doi:10.1038/s41591-019-0584-2 · Cited by 569 · see citing works
Proteogenomic Characterization of Endometrial Carcinoma
Dou, Y., Kawaler, E. A., Cui Zhou, D., Gritsenko, M. A., Huang, C., Blumenberg, L., Karpova, A., Petyuk, V. A., Savage, S. R., Satpathy, S., et al. (2020) · Cell · doi:10.1016/j.cell.2020.01.026 · Cited by 485 · see citing works
LncRNA LINRIS stabilizes IGF2BP2 and promotes the aerobic glycolysis in colorectal cancer
Wang, Y., Lu, J.-H., Wu, Q.-N., Jin, Y., Wang, D.-S., Chen, Y.-X., Liu, J., Luo, X.-J., Meng, Q., Pu, H.-Y., et al. (2019) · Molecular Cancer · doi:10.1186/s12943-019-1105-0 · Cited by 507 · see citing works
Cancer statistics for adults aged 85 years and older, 2019
DeSantis, C. E., Miller, K. D., Dale, W., Mohile, S. G., Cohen, H. J., Leach, C. R., Goding Sauer, A., Jemal, A., & Siegel, R. L. (2019) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21577 · Cited by 370 · see citing works
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Exploring immunotherapy in colorectal cancer
Weng, J., Li, S., Zhu, Z., Liu, Q., Zhang, R., Yang, Y., & Li, X. (2022) · Journal of Hematology & Oncology · doi:10.1186/s13045-022-01294-4 · Cited by 355 · see citing works
Global prevalence of depression among breast cancer patients: a systematic review and meta-analysis
Pilevarzadeh, M., Amirshahi, M., Afsargharehbagh, R., Rafiemanesh, H., Hashemi, S.-M., & Balouchi, A. (2019) · Breast Cancer Research and Treatment · doi:10.1007/s10549-019-05271-3 · Cited by 353 · see citing works
Cancer Disparities and Health Equity: A Policy Statement From the American Society of Clinical Oncology
Patel, M. I., Lopez, A. M., Blackstock, W., Reeder-Hayes, K., Moushey, E. A., Phillips, J., & Tap, W. (2020) · Journal of Clinical Oncology · doi:10.1200/jco.20.00642 · Cited by 338 · see citing works
Metastatic patterns and survival outcomes in patients with stage IV colon cancer: A population-based analysis
Wang, J., Li, S., Liu, Y., Zhang, C., Li, H., & Lai, B. (2020) · Cancer Medicine · doi:10.1002/cam4.2673 · Cited by 308 · see citing works
Lower Airway Dysbiosis Affects Lung Cancer Progression
Tsay, J.-C. J., Wu, B. G., Sulaiman, I., Gershner, K., Schluger, R., Li, Y., Yie, T.-A., Meyn, P., Olsen, E., Perez, L., et al. (2021) · Cancer Discovery · doi:10.1158/2159-8290.cd-20-0263 · Cited by 322 · see citing works
Public Health Challenges and Responses to the Growing Ageing Populations
Khan, H. T. A., Addo, K. M., & Findlay, H. (2024) · Public Health Challenges · doi:10.1002/puh2.213 · Cited by 298 · see citing works
Evaluation of deep learning detection and classification towards computer-aided diagnosis of breast lesions in digital X-ray mammograms
Al-antari, M. A., Han, S.-M., & Kim, T.-S. (2020) · Computer Methods and Programs in Biomedicine · doi:10.1016/j.cmpb.2020.105584 · Cited by 264 · see citing works
Prevalence of anxiety among breast cancer patients: a systematic review and meta-analysis
Hashemi, S.-M., Rafiemanesh, H., Aghamohammadi, T., Badakhsh, M., Amirshahi, M., Sari, M., Behnamfar, N., & Roudini, K. (2020) · Breast Cancer · doi:10.1007/s12282-019-01031-9 · Cited by 243 · see citing works
Adolescent and young adult oncology—past, present, and future
Close, A. G., Dreyzin, A., Miller, K. D., Seynnaeve, B. K. N., & Rapkin, L. B. (2019) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21585 · Cited by 225 · see citing works
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Deep learning to distinguish pancreatic cancer tissue from non-cancerous pancreatic tissue: a retrospective study with cross-racial external validation
Liu, K.-L., Wu, T., Chen, P.-T., Tsai, Y. M., Roth, H., Wu, M.-S., Liao, W.-C., & Wang, W. (2020) · The Lancet Digital Health · doi:10.1016/s2589-7500(20)30078-9 · Cited by 222 · see citing works
CAR T‐Cell‐Based gene therapy for cancers: new perspectives, challenges, and clinical developments
Jogalekar, M. P., Rajendran, R. L., Khan, F., Dmello, C., Gangadaran, P., & Ahn, B.-C. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.925985 · Cited by 214 · see citing works
Time‐Dependent Photodynamic Therapy for Multiple Targets: A Highly Efficient AIE‐Active Photosensitizer for Selective Bacterial Elimination and Cancer Cell Ablation
Li, Q., Li, Y., Min, T., Gong, J., Du, L., Phillips, D. L., Liu, J., Lam, J. W. Y., Sung, H. H. Y., Williams, I. D., et al. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.201909706 · Cited by 211 · see citing works
Integrated Analysis of lncRNA–Mediated ceRNA Network in Lung Adenocarcinoma
Wu, X., Sui, Z., Zhang, H., Wang, Y., & Yu, Z. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.554759 · Cited by 198 · see citing works
Mechanisms of Taxane Resistance
Maloney, S., Spring, C., Morejon-Lasso, L., & Prosperi, J. (2020) · Cancers · doi:10.3390/cancers12113323 · Cited by 198 · see citing works
Good Steel Used in the Blade: Well‐Tailored Type‐I Photosensitizers with Aggregation‐Induced Emission Characteristics for Precise Nuclear Targeting Photodynamic Therapy
Kang, M., Zhang, Z., Xu, W., Wen, H., Zhu, W., Wu, Q., Wu, H., Gong, J., Wang, Z., Wang, D., et al. (2021) · Advanced Science · doi:10.1002/advs.202100524 · Cited by 193 · see citing works
Phase III study of adjuvant ipilimumab (3 or 10 mg/kg) versus high-dose interferon alfa-2b for resected high-risk melanoma: North American Intergroup E1609
Tarhini, A. A., Lee, S. J., Hodi, F. S., Rao, U. N. M., Cohen, G. I., Hamid, O., Hutchins, L. F., Sosman, J. A., Kluger, H. M., Eroglu, Z., et al. (2020) · Journal of Clinical Oncology · doi:10.1200/jco.19.01381 · Cited by 184 · see citing works
Deep learning-enabled pelvic ultrasound images for accurate diagnosis of ovarian cancer in China: A retrospective, multicentre, diagnostic study
Gao, Y., Zeng, S., Xu, X., Li, H., Yao, S., Song, K., Li, X., Chen, L., Tang, J., Xing, H., et al. (2022) · The Lancet Digital Health · doi:10.1016/s2589-7500(21)00278-8 · Cited by 185 · see citing works
CDK4/6 inhibition promotes immune infiltration in ovarian cancer and synergizes with PD-1 blockade in a B cell-dependent manner
Zhang, Q.-F., Li, J., Jiang, K., Wang, R., Ge, J.-L., Yang, H., Liu, S.-J., Jia, L.-T., Wang, L., & Chen, B.-L. (2020) · Theranostics · doi:10.7150/thno.44871 · Cited by 177 · see citing works
Stimuli responsive nanosonosensitizers for sonodynamic therapy
Jiang, Z., Xiao, W., & Fu, Q. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.08.003 · Cited by 173 · see citing works
Defeating relapsed and refractory malignancies through a nano-enabled mitochondria-mediated respiratory inhibition and damage pathway
Yang, Z., Wang, J., Liu, S., Li, X., Miao, L., Yang, B., Zhang, C., He, J., Ai, S., & Guan, W. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2019.119580 · Cited by 165 · see citing works
Pretransplant solid organ malignancy and organ transplant candidacy: A consensus expert opinion statement
Al-Adra, D. P., Hammel, L., Roberts, J., Woodle, E. S., Levine, D., Mandelbrot, D., Verna, E., Locke, J., D’Cunha, J., Farr, M., et al. (2021) · American Journal of Transplantation · doi:10.1111/ajt.16318 · Cited by 163 · see citing works
Diabetes and cancer: Epidemiological and biological links
Wang, M., Yang, Y., & Liao, Z. (2020) · World Journal of Diabetes · doi:10.4239/wjd.v11.i6.227 · Cited by 158 · see citing works
A systematic review on the prevalence of symptoms of depression, anxiety and distress in long‐term cancer survivors: Implications for primary care
Brandenbarg, D., Maass, S. W. M. C., Geerse, O. P., Stegmann, M. E., Handberg, C., Schroevers, M. J., & Duijts, S. F. A. (2019) · European Journal of Cancer Care · doi:10.1111/ecc.13086 · Cited by 148 · see citing works
Molecular Engineered Squaraine Nanoprobe for NIR-II/Photoacoustic Imaging and Photothermal Therapy of Metastatic Breast Cancer
Yao, D., Wang, Y., Zou, R., Bian, K., Liu, P., Shen, S., Yang, W., Zhang, B., & Wang, D. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b20147 · Cited by 151 · see citing works
Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1
Hsu, E.-C., Rice, M. A., Bermudez, A., Marques, F. J. G., Aslan, M., Liu, S., Ghoochani, A., Zhang, C. A., Chen, Y.-S., Zlitni, A., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1905384117 · Cited by 146 · see citing works
Mutations in key driver genes of pancreatic cancer: molecularly targeted therapies and other clinical implications
Hu, H.-F., Ye, Z., Qin, Y., Xu, X.-W., Yu, X.-J., Zhuo, Q.-F., & Ji, S.-R. (2021) · Acta Pharmacologica Sinica · doi:10.1038/s41401-020-00584-2 · Cited by 149 · see citing works
Increasing Incidence of Colorectal Cancer in Young Adults
Loomans-Kropp, H. A., & Umar, A. (2019) · Journal of Cancer Epidemiology · doi:10.1155/2019/9841295 · Cited by 148 · see citing works
A Four-Chemokine Signature Is Associated with a T-cell–Inflamed Phenotype in Primary and Metastatic Pancreatic Cancer
Romero, J. M., Grünwald, B., Jang, G.-H., Bavi, P. P., Jhaveri, A., Masoomian, M., Fischer, S. E., Zhang, A., Denroche, R. E., Lungu, I. M., et al. (2020) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-19-2803 · Cited by 146 · see citing works
Acceptance and commitment therapy for breast cancer survivors with fear of cancer recurrence: A 3-arm pilot randomized controlled trial.
Johns, S. A., Stutz, P. V., Talib, T. L., Cohee, A. A., Beck‐Coon, K. A., Brown, L. F., Wilhelm, L. R., Monahan, P. O., LaPradd, M. L., Champion, V. L., et al. (2020) · Cancer · doi:10.1002/cncr.32518 · Cited by 141 · see citing works
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Alcohol-associated liver disease—Global epidemiology
Åberg, F., Jiang, Z. G., Cortez-Pinto, H., & Männistö, V. (2024) · Hepatology · doi:10.1097/hep.0000000000000899 · Cited by 163 · see citing works
Prevalence and intensity of persistent post-surgical pain following breast cancer surgery: a systematic review and meta-analysis of observational studies
Wang, L., Cohen, J. C., Devasenapathy, N., Hong, B. Y., Kheyson, S., Lu, D., Oparin, Y., Kennedy, S. A., Romerosa, B., Arora, N., et al. (2020) · British Journal of Anaesthesia · doi:10.1016/j.bja.2020.04.088 · Cited by 142 · see citing works
Selective Progesterone Receptor Modulators—Mechanisms and Therapeutic Utility
Islam, M. S., Afrin, S., Jones, S. I., & Segars, J. (2020) · Endocrine Reviews · doi:10.1210/endrev/bnaa012 · Cited by 143 · see citing works
Gut microbiome diversity is an independent predictor of survival in cervical cancer patients receiving chemoradiation
Sims, T. T., El Alam, M. B., Karpinets, T. V., Dorta-Estremera, S., Hegde, V. L., Nookala, S., Yoshida-Court, K., Wu, X., Biegert, G. W. G., Delgado Medrano, A. Y., et al. (2021) · Communications Biology · doi:10.1038/s42003-021-01741-x · Cited by 135 · see citing works
New Horizons in KRAS-Mutant Lung Cancer: Dawn After Darkness
Yang, H., Liang, S.-Q., Schmid, R. A., & Peng, R.-W. (2019) · Frontiers in Oncology · doi:10.3389/fonc.2019.00953 · Cited by 129 · see citing works
An in vitro vascularized micro-tumor model of human colorectal cancer recapitulates in vivo responses to standard-of-care therapy
Hachey, S. J., Movsesyan, S., Nguyen, Q. H., Burton-Sojo, G., Tankazyan, A., Wu, J., Hoang, T., Zhao, D., Wang, S., Hatch, M. M., et al. (2021) · Lab on a Chip · doi:10.1039/d0lc01216e · Cited by 124 · see citing works
Lipid accumulation in macrophages confers protumorigenic polarization and immunity in gastric cancer
Luo, Q., Zheng, N., Jiang, L., Wang, T., Zhang, P., Liu, Y., Zheng, P., Wang, W., Xie, G., Chen, L., et al. (2020) · Cancer Science · doi:10.1111/cas.14616 · Cited by 126 · see citing works
Perioperative COX2 and β‐adrenergic blockade improves biomarkers of tumor metastasis, immunity, and inflammation in colorectal cancer: A randomized controlled trial
Haldar, R., Ricon‐Becker, I., Radin, A., Gutman, M., Cole, S. W., Zmora, O., & Ben‐Eliyahu, S. (2020) · Cancer · doi:10.1002/cncr.32950 · Cited by 122 · see citing works
The B7-H3–Targeting Antibody–Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models
Kendsersky, N. M., Lindsay, J., Kolb, E. A., Smith, M. A., Teicher, B. A., Erickson, S. W., Earley, E. J., Mosse, Y. P., Martinez, D., Pogoriler, J., et al. (2021) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-20-4221 · Cited by 120 · see citing works
Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer
Lu, W., Yu, W., He, J., Liu, W., Yang, J., Lin, X., Zhang, Y., Wang, X., Jiang, W., Luo, J., et al. (2021) · EMBO Molecular Medicine · doi:10.15252/emmm.202012798 · Cited by 112 · see citing works
Loss‐of‐Function Genetic Screening Identifies Aldolase A as an Essential Driver for Liver Cancer Cell Growth Under Hypoxia
Niu, Y., Lin, Z., Wan, A., Sun, L., Yan, S., Liang, H., Zhan, S., Chen, D., Bu, X., Liu, P., et al. (2021) · Hepatology · doi:10.1002/hep.31846 · Cited by 115 · see citing works
Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer
Brown, W. S., McDonald, P. C., Nemirovsky, O., Awrey, S., Chafe, S. C., Schaeffer, D. F., Li, J., Renouf, D. J., Stanger, B. Z., & Dedhar, S. (2020) · Cell Reports Medicine · doi:10.1016/j.xcrm.2020.100131 · Cited by 111 · see citing works
Nano delivery of simvastatin targets liver sinusoidal endothelial cells to remodel tumor microenvironment for hepatocellular carcinoma
Yu, Z., Guo, J., Liu, Y., Wang, M., Liu, Z., Gao, Y., & Huang, L. (2022) · Journal of Nanobiotechnology · doi:10.1186/s12951-021-01205-8 · Cited by 114 · see citing works
SHP-2 and PD-L1 Inhibition Combined with Radiotherapy Enhances Systemic Antitumor Effects in an Anti–PD-1–Resistant Model of Non–Small Cell Lung Cancer
Chen, D., Barsoumian, H. B., Yang, L., Younes, A. I., Verma, V., Hu, Y., Menon, H., Wasley, M., Masropour, F., Mosaffa, S., et al. (2020) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-19-0744 · Cited by 107 · see citing works
The effects of acceptance and commitment therapy on the psychological and physical outcomes among cancer patients: A meta-analysis with trial sequential analysis
Zhao, C., Lai, L., Zhang, L., Cai, Z., Ren, Z., Shi, C., Luo, W., & Yan, Y. (2021) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2020.110304 · Cited by 104 · see citing works
A Role for NF-κB in Organ Specific Cancer and Cancer Stem Cells
Kaltschmidt, C., Banz-Jansen, C., Benhidjeb, T., Beshay, M., Förster, C., Greiner, J., Hamelmann, E., Jorch, N., Mertzlufft, F., Pfitzenmaier, J., et al. (2019) · Cancers · doi:10.3390/cancers11050655 · Cited by 102 · see citing works
Gut microbial diversity and genus-level differences identified in cervical cancer patients versus healthy controls
Sims, T. T., Colbert, L. E., Zheng, J., Delgado Medrano, A. Y., Hoffman, K. L., Ramondetta, L., Jazaeri, A., Jhingran, A., Schmeler, K. M., Daniel, C. R., et al. (2019) · Gynecologic Oncology · doi:10.1016/j.ygyno.2019.09.002 · Cited by 100 · see citing works
Early Diagnosis of Pancreatic Cancer: The Key for Survival
Gheorghe, G., Bungau, S., Ilie, M., Behl, T., Vesa, C. M., Brisc, C., Bacalbasa, N., Turi, V., Costache, R. S., & Diaconu, C. C. (2020) · Diagnostics · doi:10.3390/diagnostics10110869 · Cited by 100 · see citing works
Recent Advances on Drug-Loaded Mesenchymal Stem Cells With Anti-neoplastic Agents for Targeted Treatment of Cancer
Babajani, A., Soltani, P., Jamshidi, E., Farjoo, M. H., & Niknejad, H. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2020.00748 · Cited by 99 · see citing works
Atezolizumab for the treatment of breast cancer
Reddy, S. M., Carroll, E., & Nanda, R. (2020) · Expert Review of Anticancer Therapy · doi:10.1080/14737140.2020.1732211 · Cited by 94 · see citing works
RAS, wanted dead or alive: Advances in targeting RAS mutant cancers
Stalnecker, C. A., & Der, C. J. (2020) · Science Signaling · doi:10.1126/scisignal.aay6013 · Cited by 90 · see citing works
The Hippo Signaling Pathway in Drug Resistance in Cancer
Zeng, R., & Dong, J. (2021) · Cancers · doi:10.3390/cancers13020318 · Cited by 89 · see citing works
Genome engineering of induced pluripotent stem cells to manufacture natural killer cell therapies
Shankar, K., Capitini, C. M., & Saha, K. (2020) · Stem Cell Research & Therapy · doi:10.1186/s13287-020-01741-4 · Cited by 85 · see citing works
Axial pharmaceutical properties of liposome in cancer therapy: Recent advances and perspectives
Kiaie, S. H., Mojarad-Jabali, S., Khaleseh, F., Allahyari, S., Taheri, E., Zakeri-Milani, P., & Valizadeh, H. (2020) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2020.119269 · Cited by 87 · see citing works
Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors
Richters, A., Doyle, S. K., Freeman, D. B., Lee, C., Leifer, B. S., Jagannathan, S., Kabinger, F., Koren, J. V., Struntz, N. B., Urgiles, J., et al. (2021) · Cell Chemical Biology · doi:10.1016/j.chembiol.2020.10.001 · Cited by 86 · see citing works
Mindfulness-based stress reduction can alleviate cancer- related fatigue: A meta-analysis
Xie, C., Dong, B., Wang, L., Jing, X., Wu, Y., Lin, L., & Tian, L. (2020) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2019.109916 · Cited by 84 · see citing works
Factors associated with missed and misinterpreted cases of pancreatic ductal adenocarcinoma
Kang, J. D., Clarke, S. E., & Costa, A. F. (2021) · European Radiology · doi:10.1007/s00330-020-07307-5 · Cited by 84 · see citing works
Single-cell sequencing reveals trajectory of tumor-infiltrating lymphocyte states in pancreatic cancer
Schalck, A., Sakellariou-Thompson, D., Forget, M.-A., Sei, E., Hughes, T. G., Reuben, A., Bai, S., Hu, M., Kumar, T., Hurd, M. W., et al. (2022) · Cancer Discovery · doi:10.1158/2159-8290.cd-21-1248 · Cited by 85 · see citing works
The Evolutionary Landscape of Treatment for BRAFV600E Mutant Metastatic Colorectal Cancer
Mauri, G., Bonazzina, E., Amatu, A., Tosi, F., Bencardino, K., Gori, V., Massihnia, D., Cipani, T., Spina, F., Ghezzi, S., et al. (2021) · Cancers · doi:10.3390/cancers13010137 · Cited by 73 · see citing works
Expression and role of the G protein-coupled estrogen receptor (GPR30/GPER) in the development and immune response in female reproductive cancers
Hernández-Silva, C. D., Villegas-Pineda, J. C., & Pereira-Suárez, A. L. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00544 · Cited by 74 · see citing works
The effects of age and systemic metabolism on anti-tumor T cell responses
Drijvers, J. M., Sharpe, A. H., & Haigis, M. C. (2020) · eLife · doi:10.7554/elife.62420 · Cited by 69 · see citing works
The Effect of Mindfulness-Based Stress Reduction Group Counseling on Psychological and Inflammatory Responses of the Women With Breast Cancer
Mirmahmoodi, M., Mangalian, P., Ahmadi, A., & Dehghan, M. (2020) · Integrative Cancer Therapies · doi:10.1177/1534735420946819 · Cited by 67 · see citing works
Chemotherapy in metastatic castration-resistant prostate cancer: Current scenario and future perspectives
Ruiz de Porras, V., Font, A., & Aytes, A. (2021) · Cancer Letters · doi:10.1016/j.canlet.2021.08.033 · Cited by 65 · see citing works
Enhancing the landscape of colorectal cancer using targeted deep sequencing
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Authors: Siegel, R. L., Miller, K. D., & Jemal, A.
Affiliations: American Cancer Society (US)
Corresponding author: Siegel, Rebecca L.
ORCID: Siegel, Rebecca L.
Miller, Kimberly D.
Jemal, Ahmedin
Venue: CA: A Cancer Journal for Clinicians
Publisher: Wiley
Published: 2019-01
Volume: 69
Issue: 1
Pages: 7-34
ISSN: 0007-9235 (ISSN-L)
1542-4863
DOI: 10.3322/caac.21551
OpenAlex: W2911188335
Cited by: 20,160
References: 81
Citations by year: 2026: 194 · 2025: 659 · 2024: 1359 · 2023: 1872 · 2022: 2727 · 2021: 4743 · 2020: 6235 · 2019: 2341 · 2018: 5 · 2017: 6 · 2016: 1 · 2015: 1 · 2012: 1
FWCI: 1689.30
Type: journal article
Language: en
Open access: gold
doi.org
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 7 d)
Locations: CA A Cancer Journal for Clinicians (publishedVersion)
PubMed (publishedVersion)
Funders: American Cancer Society
Topics: Health Sciences › Medicine › Oncology › Global Cancer Incidence and Screening
Health Sciences › Medicine › Oncology › Colorectal Cancer Screening and Detection
Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Economic and Financial Impacts of Cancer
Keywords: cancer incidence, cancer mortality, cancer survival, cancer projections, racial disparities in cancer mortality, socioeconomic disparities, county-level disparities, cervical cancer, lung cancer, liver cancer, cancer control, cancer prevention, early detection
MeSH terms: American Cancer Society, Ethnicity, Female, Humans, Male, Neoplasms, Socioeconomic Factors, United States, Incidence, Survival Rate, Health Status Disparities, Healthcare Disparities

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