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Drak2 Is Upstream of p70S6 Kinase: Its Implication in Cytokine-Induced Islet Apoptosis, Diabetes, and Islet Transplantation

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Quercetin Alleviated Inflammasome-Mediated Pyroptosis and Modulated the mTOR/P70S6/P6/eIF4E/4EBP1 Pathway in Ischemic Stroke

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MiR-99a Inhibits Cell Proliferation and Tumorigenesis through Targeting mTOR in Human Anaplastic Thyroid Cancer

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mTOR as a Potential Target for the Treatment of Microbial Infections, Inflammatory Bowel Diseases, and Colorectal Cancer

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Hydrogen Peroxide Induces Cell Cycle Arrest in Cardiomyoblast H9c2 Cells, Which Is Related to Hypertrophy

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Gossypol sensitizes the antitumor activity of 5-FU through down-regulation of thymidylate synthase in human colon carcinoma cells

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Activation of the mTORC1 and STAT3 pathways promotes the malignant transformation of colitis in mice

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A Semi-Physiological Population Model to Quantify the Effect of Hematocrit on Everolimus Pharmacokinetics and Pharmacodynamics in Cancer Patients

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Identification of proteins associated with development of psoriatic arthritis in peripheral blood mononuclear cells: a quantitative iTRAQ-based proteomics study

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Substrate Reduction Therapy Reverses Mitochondrial, mTOR, and Autophagy Alterations in a Cell Model of Gaucher Disease

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Assessing Metabolic Changes in Response to mTOR Inhibition in a Mantle Cell Lymphoma Xenograft Model Using AcidoCEST MRI

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Profiling of human lymphocytes reveals a specific network of protein kinases modulated by endurance training status

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Recombinant Human Erythropoietin Protects Against Hippocampal Damage in Developing Rats with Seizures by Modulating Autophagy via the S6 Protein in a Time-Dependent Manner

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Morusin and mulberrin extend the lifespans of yeast and C. elegans via suppressing nutrient-sensing pathways

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Tris (dibenzylideneacetone) dipalladium: a small-molecule palladium complex is effective in inducing apoptosis in chronic lymphocytic leukemia B-cells

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The mTOR downstream regulator (p-4EBP1) is a novel independent prognostic marker in ovarian cancer

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Prazosin induces p53-mediated autophagic cell death in H9C2 cells

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Prediction of genetic risk factors of atherosclerosis using various bioinformatic tools

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Low-dose ionizing radiation exposure represses the cell cycle and protein synthesis pathways in in vitro human primary keratinocytes and U937 cell lines

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Pharmacological modulation of PI3K/PTEN/Akt/mTOR/ERK signaling pathways in ischemic injury: a mechanistic perspective

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TMT-Based Quantitative Proteomics Analysis of the Fish-Borne Spoiler Shewanella putrefaciens Subjected to Cold Stress Using LC-MS/MS

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Protein metabolic changes and nucleolus organizer regions activity in the lymphocytes of neonatal calves during the development of respiratory diseases

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Hepatic expression of proteasome subunit alpha type‐6 is upregulated during viral hepatitis and putatively regulates the expression of ISG 15 ubiquitin‐like modifier, a proviral host gene in hepatitis C virus infection

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Transcriptome Analysis of Marbled Rockfish Sebastiscus marmoratus under Salinity Stress

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Mechanistic Target of Rapamycin Inhibition Prevents Coronary Artery Remodeling in a Murine Model of Kawasaki Disease

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l-Alanylglutamine inhibits signaling proteins that activate protein degradation, but does not affect proteins that activate protein synthesis after an acute resistance exercise

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Evaluation of B‐cell intracellular signaling by monitoring the PI3K‐Akt axis in patients with common variable immunodeficiency and activated phosphoinositide 3‐kinase delta syndrome

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Impact of Pyrrolidine Dithiocarbamate and Interleukin-6 on Mammalian Target of Rapamycin Complex 1 Regulation and Global Protein Translation

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SILAC-based quantitative proteomics reveals pleiotropic, phenotypic modulation in primary murine macrophages infected with the protozoan pathogen Leishmania donovani

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Involvement of mTOR in Type 2 CRF Receptor Inhibition of Insulin Signaling in Muscle Cells

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Investigation of the effects of drugs effective on PI3K-AKT signaling pathway in colorectal cancer alone and in combination

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IKBKE inhibits TSC1 to activate the mTOR/S6K pathway for oncogenic transformation

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The coordinated management of ribosome and translation during injury and regeneration

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Oligogalacturonides inhibit growth and induce changes in S6K phosphorylation in maize (Zea mays L. var. Chalqueño)

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Structure-based modification of pyrazolone derivatives to inhibit mTORC1 by targeting the leucyl-tRNA synthetase-RagD interaction

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S6 protein kinase activates Juvenile Hormone and vitellogenin production in the cockroach B lattella germanica

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Kinase Inhibitors with Antiepileptic Properties Identified with a Novel in Vitro Screening Platform

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Roles of PI3K/AKT/PTEN Pathway in the Pathogenesis of Parkinson’s Disease and the Neuropsychiatric Symptoms

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Downregulation of mTOR by lentivirus inhibits prostate cancer cell growth.

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A Review of Compounds for Prevention of Colorectal Cancer

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Adrenal Cortical Carcinoma and Additional Rare Pathologic Findings in Multi-Organs in a Birt-Hogg-Dubé Syndrome Patient: With an Emphasis on the Molecular Characteristics of Adrenal Cortical Carcinoma

Kim, D. S., Murvelashvili, N., Hamidi, O., & Jia, L. (2022) · International Journal of Surgical Pathology · doi:10.1177/10668969221117246 · Cited by 4

Comparative transcriptome analysis of low- and high-latitude populations of Charybdis japonica under temperature stress

Sun, S., He, Z., Zhang, F., & Han, Z. (2024) · Frontiers in Marine Science · doi:10.3389/fmars.2024.1491685 · Cited by 4

Downregulation of RelA (p65) by Rapamycin Inhibits Murine Adipocyte Differentiation and Reduces Fat Mass of C57BL/6J Mice despite High Fat Diet

Ray, P. D., Maclellan, R. A., He, J., Liu, Z., & Wu, J. (2014) · ISRN Obesity · doi:10.1155/2014/540582 · Cited by 4

4′‐Hydroxychalcone Induces Ferroptosis in Glioblastoma Through the xCT / GSH / GPX4 Axis Under the Regulation of the AKT / mTORC1 / 4EBP1 Pathway

Zhao, R., Li, Y., Liu, Y., Yang, X., Li, H., Wu, C., Zhao, Z., Yan, Y., Liu, Z., Li, S., et al. (2025) · Phytotherapy Research · doi:10.1002/ptr.70004 · Cited by 3

Monitoring endoplasmic reticulum stress responsive mRNAs by RNA sequencing

Okuda, T., Wakaguri, H., Suzuki, Y., & Sugano, S. (2012) · Gene · doi:10.1016/j.gene.2012.03.048 · Cited by 3

The Role of Ribosome Biogenesis in Skeletal Muscle Hypertrophy

Figueiredo, V. C., & McCarthy, J. J. (2017) · Springer eBooks · doi:10.1007/978-981-10-3292-9_6 · Cited by 3

Diverse Mechanisms of Translation Regulation and Their Role in Cancer

Villa, N., & Fraser, C. S. (2014) · Springer eBooks · doi:10.1007/978-94-017-9078-9_3 · Cited by 3

Downstream Targets of mTORC1

Fonseca, B. D., & Proud, C. G. (2009) · Humana Press eBooks · doi:10.1007/978-1-60327-271-1_9 · Cited by 5

Impact of Rapamycin on Longevity: Updated Insights

Sanati, M., Afshari, A. R., Aminyavari, S., Banach, M., & Sahebkar, A. (2024) · Archives of Medical Science · doi:10.5114/aoms/191565 · Cited by 3

Unraveling the impact of ZZZ3 on the mTOR/ribosome pathway in human embryonic stem cells homeostasis

Conte, M. L., Lucchino, V., Scalise, S., Zannino, C., Valente, D., Rossignoli, G., Murfuni, M. S., Cicconetti, C., Scaramuzzino, L., Matassa, D. S., et al. (2024) · Stem Cell Reports · doi:10.1016/j.stemcr.2024.04.002 · Cited by 2

Inhibition of protein translation under matrix-deprivation stress in breast cancer cells

Warrier, S., Srinivasan, S., Chedere, A., & Rangarajan, A. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2023.1124514 · Cited by 2

Molecular Genetic Markers in Female Reproductive Cancers

Wang, T., Davidson, B., Buckhaults, P., Huang, C., & Pohl, G. (2010) · Journal of Oncology · doi:10.1155/2010/307460 · Cited by 2

The Regulation of Mammalian Target of Rapamycin

Xie, J. (2012) · Figshare · Cited by 2

17β-estradiol maintains extracellular matrix homeostasis of nucleus pulposus cells by activating p70 S6K1 signaling pathway

Liu, T., Li, Z., Zhang, W., Guo, X., Liu, G., Yang, D., & Yang, S. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1564458 · Cited by 1

Target of Rapamycin (TOR) and Autophagy in Chronic Hepatitis C Virus Infection: Relation to Disease Activity

Lashen, S. A. A. (2017) · Journal of Liver Research Disorders & Therapy · doi:10.15406/jlrdt.2017.03.00056

Downstream of mTOR: Translational Control of Cancer

Dowling, R. J. O., & Sonenberg, N. (2009) · Humana Press eBooks · doi:10.1007/978-1-60327-271-1_10 · Cited by 1

Everolimus: Emerging Evidence of its Therapeutic Impact in Patients with Advanced Renal Cell Carcinoma

Cho, D. C. (2010) · Clinical Medicine Reviews in Oncology · doi:10.4137/cmro.s3428 · Cited by 1

S6K (S6 Kinase)

Pavan, I. C. B., Silva, F. R., Morelli, A. P., & Simabuco, F. M. (2016) · Springer eBooks · doi:10.1007/978-1-4614-6438-9_101816-1 · Cited by 1

Regulation of autophagy and mTOR during Semliki Forest virus infection

Eng, K. E. (2012) · Figshare

The Role of TIPE2 in the Regulation of Inflammation and Tumorigenesis

Johnson, D. (2013) · Scholarly Commons (University of Pennsylvania)

Targeting the mTOR Pathway for Tumor Therapeutics

Chen, W. (2009) · Wiley eBooks · doi:10.1002/9780470538951.ch22

Rutas de señalización de la insulina en plantas

Peña, E. M. B., Domínguez, A. J., Fierros‐Romero, G., Mellado-Rojas, M. E., de la Cruz, H. R., & Pineda, E. G. (2011) · Ciencia Nicolaita · doi:10.35830/cn.vi54.31

Clinical potential of the mTOR effectors S6K1, S6K2 and 4EBP1 in breast cancer

Karlsson, E. A. (2014) · Linköping University Electronic Press eBooks · doi:10.3384/diss.diva-104180

mTOR-Dependent Regulation of Ribosomal Gene Transcription Requires S6K1 and Is Mediated by Phosphorylation of the Carboxy-Terminal Activation Domain of the Nucleolar Transcription Factor UBF†

Hannan, K. M., Brandenburger, Y., Jenkins, A., Sharkey, K., Cavanaugh, A. H., Rothblum, L. I., Moss, T., Poortinga, G., McArthur, G. A., Pearson, R. B., et al. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.23.8862-8877.2003 · Cited by 489

THE mTOR SIGNALING PATHWAY AND THE REGULATION OF CELL GROWTH

Wang, Z. (2007) · Acta Biophysica Sinica · Cited by 7

Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks

Magnuson, B., Ekim, B., & Fingar, D. C. (2012) · Biochemical Journal · doi:10.1042/bj20110892 · Cited by 1,015

Ribosomal Protein S6 and S6 Kinases

Pende, M., & Treins, C. (2014) · Springer eBooks · doi:10.1007/978-94-017-9078-9_16

Ribosomal S6 Kinase Signaling and the Control of Translation

Dufner, A., & Thomas, G. (1999) · Experimental Cell Research · doi:10.1006/excr.1999.4683 · Cited by 676