The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Evidence for a General Relationship between the Induced Level of DNA Double-strand Breakage and Cell-killing after X-irradiation of Mammalian Cells
Abstract
X-ray-induced DNA double-strand breakage (dsb) and lethal lesion induction have been examined using normal and transformed fibroblasts of rodent and human origin. DNA dsb induction varied markedly among the different cell types and was found to reflect radiosensitivity. Linear relationships were found between DNA dsb and lethal lesion induction which were not significantly different for each cell type, suggesting a comparable probability of conversion of DNA dsb into a lethal lesion. The implications of these findings for models of cell survival are discussed.
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Citations
Cites
ACTION OF X-RAYS ON MAMMALIAN CELLS
Puck, T. T., & Marcus, P. I. (1956) · The Journal of Experimental Medicine · doi:10.1084/jem.103.5.653 · Cited by 1,696
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Haimovitz-Friedman, A., Kan, C. C., Ehleiter, D., Persaud, R. S., McLoughlin, M., Fuks, Z., & Kolesnick, R. N. (1994) · The Journal of experimental medicine · doi:10.1084/jem.180.2.525 · Cited by 905
Friedland, W., Dingfelder, M., Kundrát, P., & Jacob, P. (2011) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis · doi:10.1016/j.mrfmmm.2011.01.003 · Cited by 386
The role of DNA double strand breaks in lonizing radiation‐induced killing of eukaryotic cells
Lliakis, G. (1991) · BioEssays · doi:10.1002/bies.950131204 · Cited by 329
Steel, G. G., McMillan, T. J., & Peacock, J. H. (1989) · International Journal of Radiation Biology · doi:10.1080/09553008914552491 · Cited by 290
A link between double-strand break-related repair and V(D)J recombination: the scid mutation.
Hendrickson, E. A., Qin, X. Q., Bump, E. A., Schatz, D. G., Oettinger, M., & Weaver, D. T. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.10.4061 · Cited by 286
Metadata
- Authors
- Radford, I. R.
- Venue
- International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
- Publisher
- Informa UK Limited
- Published
- 1985-01
- Volume
- 49
- Issue
- 4
- Pages
- 611-620
- ISSN
- 0020-7616 (ISSN-L)
- OpenAlex
- W2201456435
- Cited by
- 260
- References
- 1
- FWCI
- 9.04
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Evidence for a General Relationship between the Induced Level of DNA Double-strand Breakage and Cell-killing after X-irradiation of Mammalian Cells. https://app.cochat.ai/papers/10.1080/09553008514552861
- The paper
- Radford, I. R. (1985). Evidence for a General Relationship between the Induced Level of DNA Double-strand Breakage and Cell-killing after X-irradiation of Mammalian Cells. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine. https://doi.org/10.1080/09553008514552861
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
