The DOI matches its Crossref record; 34 of the 35 references it cites were found in a registry or an index.
The antioxidant and radical scavenging activities of black pepper (Piper nigrum) seeds
Abstract
Water and ethanol crude extracts from black pepper (Piper nigrum) were investigated for their antioxidant and radical scavenging activities in six different assay, namely, total antioxidant activity, reducing power, 1,1-Diphenyl-2-picryl-hydrazyl (DPPH) free radical scavenging, superoxide anion radical scavenging, hydrogen peroxide scavenging, and metal chelating activities. Both water extract (WEBP) and ethanol extract (EEBP) of black pepper exhibited strong total antioxidant activity. The 75 microg/ml concentration of WEBP and EEBP showed 95.5% and 93.3% inhibition on peroxidation of linoleic acid emulsion, respectively. On the other hand, at the same concentration, standard antioxidants such as butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT) and alpha-tocopherol exhibited 92.1%, 95.0%, and 70.4% inhibition on peroxidation of linoleic acid emulsion, respectively. Also, total phenolic content in both WEBP and EEBP were determined as gallic acid equivalents. The total phenolics content of water and ethanol extracts were determined by the Folin-Ciocalteu procedure and 54.3 and 42.8 microg gallic acid equivalent of phenols was detected in 1 mg WEBP and EEBP.
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“Black pepper seed powder (active principle, piperine) also has antioxidant effects and increases the bioavailability of various nutrients through a number of mechanisms [33].”
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Cites
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Research works printed but not linked: 3
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- Gülçin İ, 2005, Toxicology
- Gülçin İ, 2004, Ital J Food Sci, 16, 17
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Metadata
- Authors
- Gülçin, İ.
- Venue
- International Journal of Food Sciences and Nutrition
- Publisher
- Informa UK Limited
- Published
- 2005-01
- Volume
- 56
- Issue
- 7
- Pages
- 491-499
- ISSN
- 0963-7486 (ISSN-L)
- 1465-3478
- OpenAlex
- W2073231015
- Cited by
- 323
- References
- 35
- Citations by year
- 2026: 7 · 2025: 26 · 2024: 18 · 2023: 31 · 2022: 26 · 2021: 21 · 2020: 27 · 2019: 14 · 2018: 15 · 2017: 10 · 2016: 10 · 2015: 18 · 2014: 15 · 2013: 17 · 2012: 9
- FWCI
- 4.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Food Sciences and Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Piperaceae Chemical and Biological Studies
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Physical Sciences › Chemistry › Organic Chemistry › Free Radicals and Antioxidants
- Keywords
- black pepper, seeds, antioxidant activity, free radical scavenging, DPPH radical scavenging, superoxide radical scavenging, hydrogen peroxide scavenging, metal chelating activity, reducing power, total phenolic content, aqueous extract, ethanol extract
- MeSH terms
- Ethanol, Antioxidants, Chelating Agents, Oxidation-Reduction, Plant Extracts, Seeds, Water, Lipid Peroxidation, Free Radical Scavengers, Piper nigrum
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