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Cited by 698

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

Probiotic Spectra of Lactic Acid Bacteria (LAB)

Naidu, A. S., Bidlack, W. R., Clemens, R. A.·1999·Critical Reviews in Food Science and Nutrition
DOI 10.1080/10408699991279187
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Abstract

Lactic acid bacteria (LAB) and their probio-active cellular substances exert many beneficial effects in the gastrointestinal tract. LAB prevent adherence, establishment, and replication of several enteric mucosal pathogens through several antimicrobial mechanisms. LAB also release various enzymes into the intestinal lumen and exert potential synergistic effects on digestion and alleviate symptoms of intestinal malabsoption. Consumption of LAB fermented dairy products with LAB may elicit antitumor effects. These effects are attributed to the inhibition of mutagenic activity; decrease in several enzymes implicated in the generation of carcinogens, mutagens, or tumor-promoting agents; suppression of tumors; and the epidemiology correlating dietary regimes and cancer. Specific cellular components in LAB strains seem to induce strong adjuvant effects including modulation of cell-mediated immune responses, activation of reticuloendothelial system, augmentation of cytokine pathways and regulation of interleukins, and tumor necrosis factors. Oral administration of LAB is well tolerated and proven to be safe in 143 human clinical trials and no adverse effects were reported in any of the total 7,526 subjects studied during 1961-1998. In an effort to decrease the reliance on synthetic antimicrobials and control the emerging immunocompromised host population, the time has come to carefully explore the prophylactic and therapeutic applications of probiotic LAB.

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Crossref · 10.1080/10408699991279187

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Metadata

Authors
Naidu, A. S., Bidlack, W. R., & Clemens, R. A.
Venue
Critical Reviews in Food Science and Nutrition
Publisher
Informa UK Limited
Published
1999-01
Volume
39
Issue
1
Pages
13-126
ISSN
  • 1040-8398 (ISSN-L)
  • 1549-7852
DOI
10.1080/10408699991279187
OpenAlex
W2049323790
Cited by
698
References
8
FWCI
51.95
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Probiotic Spectra of Lactic Acid Bacteria (LAB). https://app.cochat.ai/papers/10.1080/10408699991279187
The paper
Naidu, A. S., Bidlack, W. R., & Clemens, R. A. (1999). Probiotic Spectra of Lactic Acid Bacteria (LAB). Critical Reviews in Food Science and Nutrition. https://doi.org/10.1080/10408699991279187

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.