The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Chitosan-based nanoparticles as drug delivery systems: a review on two decades of research
Abstract
Chitosan (CS) is one of the most functional natural biopolymer widely used in the pharmaceutical field due to its biocompatibility and biodegradability. These privileges lead to its application in the synthesis of nanoparticles for the drug during the last two decades. This article gives rise to a general review of the different chitosan nanoparticles (CSNPs) preparation techniques: Ionic gelation, emulsion cross-linking, spray-drying, emulsion-droplet coalescence method, nanoprecipitation, reverse micellar method, desolvation method, modified ionic gelation with radial polymerisation and emulsion solvent diffusion, from the point of view of the methodological and mechanistic aspects involved. The physicochemical behaviour of CSNPs including drug loading, drug release, particles size, zeta potential and stability are briefly discussed. This review also directs to bring an outline of the major applications of CSNPs in drug delivery according to drug and route of administration. Finally, derivatives of CSNPs and CS nano-complexes are also discussed.
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Cites
Freeze-drying of nanoparticles: Formulation, process and storage considerations
ABDELWAHED, W., DEGOBERT, G., STAINMESSE, S., & FESSI, H. (2006) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2006.09.017 · Cited by 1,611
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“CSNPs have been largely used for the delivery of anti-cancer drugs including methotrexate [112], 5-flourouracil [113,114], cysplatin [115], epirubicin [116], curcumin [117,118], mitomycin C [119], docetaxel [120], doxorubicin (DOX) [49,121], paclitaxel [122] and tamoxifen [123], focussing to augment anti-tumour effica…”
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Colorectal cancer cell detection by 5-aminolaevulinic acid-loaded chitosan nano-particles
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Cited by
Harugade, A., Sherje, A. P., & Pethe, A. (2023) · Reactive and Functional Polymers · doi:10.1016/j.reactfunctpolym.2023.105634 · Cited by 474
Nanonization techniques to overcome poor water-solubility with drugs
Da Silva, F. L. O., Marques, M. B. D. F., Kato, K. C., & Carneiro, G. (2020) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2020.1750591 · Cited by 136
Yee Kuen, C., & Masarudin, M. J. (2022) · Molecules · doi:10.3390/molecules27020473 · Cited by 78
Arab-Bafrani, Z., Zabihi, E., Jafari, S. M., Khoshbin-Khoshnazar, A., Mousavi, E., Khalili, M., & Babaei, A. (2021) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2021.120828 · Cited by 39
Bassam, S. M., Ali, D. E., Awwad, Z. M., Mahmoud, S. A., & Abou-Taleb, B. A. (2024) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2024.105543 · Cited by 12
Metadata
- Authors
- Naskar, S., Kuotsu, K., & Sharma, S.
- Venue
- Journal of Drug Targeting
- Publisher
- Informa UK Limited
- Published
- 2018-09-05
- Volume
- 27
- Issue
- 4
- Pages
- 379-393
- ISSN
- 1026-7158 (ISSN-L)
- 1061-186X
- 1029-2330
- OpenAlex
- W2887267168
- Cited by
- 217
- References
- 5
- FWCI
- 9.74
- Type
- journal article
- Language
- en
- Open access
- closed
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- Naskar, S., Kuotsu, K., & Sharma, S. (2019). Chitosan-based nanoparticles as drug delivery systems: a review on two decades of research. Journal of Drug Targeting. https://doi.org/10.1080/1061186x.2018.1512112
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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