Maternal postpartum depression and infant social withdrawal among human immunodeficiency virus (HIV) positive mother–infant dyads
Abstract
Maternal postpartum depression poses significant risks for mother-child interaction and long-term infant outcomes. Human immunodeficiency virus (HIV) status has also been implicated in the development of postpartum depression, but the association between maternal depression and infant social behavior in the context of HIV infection has not been fully investigated. First, we examined the relationship between maternal postpartum depression and infant social withdrawal at 10-12 months of age in HIV-infected mothers and infants. Second, we ascertained whether infant social withdrawal could be significantly predicted by maternal postpartum depression. The sample consisted of 83 HIV-infected mother-infant dyads. Mothers were assessed for postpartum depression with the Edinburgh Postnatal Depression Scale (EPDS), and infant social withdrawal behavior was rated using the Modified Alarm Distress Baby Scale (m-ADBB). 42.2% of the mothers scored above the cut-off point for depression on the EPDS, and a third of infants (31%) were socially withdrawn. Notably, maternal depression did not predict infant social withdrawal as measured by the m-ADBB. Infant social withdrawal was also not significantly associated with failure to thrive or gender. These preliminary findings need further investigation with respect to the impact on long-term neurodevelopmental and behavioral outcomes.
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Maternal PPD did not seem to have a direct effect on child social development.
“Similarly, maternal PPD did not seem to have a direct effect on child social development.66,143”
From Consequences of maternal postpartum depression: A systematic review of maternal and infant outcomes (2019) · cites this paper as [143]
Cites
Detection of Postnatal Depression: Development of the 10-item Edinburgh Postnatal Depression Scale
Cox, J. L., Holden, J. M., & Sagovsky, R. (1987) · British Journal of Psychiatry · doi:10.1192/bjp.150.6.782 · Cited by 14,183 · see citing works
Statistics notes: Cronbach's alpha: Table 1
Bland, J. M., & Altman, D. G. (1997) · BMJ · doi:10.1136/bmj.314.7080.572 · Cited by 5,300 · see citing works
Rates and risk of postpartum depression – a meta-analysis
O'hara, M. W., & Swain, A. M. (1996) · International Review of Psychiatry · doi:10.3109/09540269609037816 · Cited by 3,116 · see citing works
Early Antiretroviral Therapy and Mortality among HIV-Infected Infants
Violari, A., Cotton, M. F., Gibb, D. M., Babiker, A. G., Steyn, J., Madhi, S. A., Jean‐Philippe, P., & McIntyre, J. A. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0800971 · Cited by 1,418 · see citing works
Self-citationGaynes, B. N., Gavin, N., Meltzer-Brody, S., Lohr, K. N., Swinson, T., Gartlehner, G., Brody, S., & Miller, W. C. (2005) · PsycEXTRA Dataset · doi:10.1037/e439372005-001 · Cited by 1,211 · see citing works
Cross-cultural and social diversity of prevalence of postpartum depression and depressive symptoms
Halbreich, U., & Karkun, S. (2006) · Journal of Affective Disorders · doi:10.1016/j.jad.2005.12.051 · Cited by 776 · see citing works
Postpartum Depression and Child Development
Tully, E. M. (1998) · Psychiatric Services · doi:10.1176/ps.49.5.707 · Cited by 654 · see citing works
Field, T. M. (1995) · Infant Behavior and Development · doi:10.1016/0163-6383(95)90003-9 · Cited by 524 · see citing works
Prevalence of depressive symptoms in late pregnancy and postpartum
Josefsson, A., Berg, G., Nordin, C., & Sydsjö, G. (2001) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1034/j.1600-0412.2001.080003251.x · Cited by 461 · see citing works
Post-partum depression and the mother-infant relationship in a South African peri-urban settlement
Cooper, P. J., Tomlinson, M., Swartz, L., Woolgar, M., Murray, L., & Molteno, C. (1999) · British Journal of Psychiatry · doi:10.1192/bjp.175.6.554 · Cited by 422 · see citing works
The Relationship between Post-natal Depression and Mother–Child Interaction
Stein, A. L., Gath, D. H., Bucher, J., Bond, A., Day, A., & Cooper, P. (1991) · The British Journal of Psychiatry · doi:10.1192/bjp.158.1.46 · Cited by 409 · see citing works
Depressive Symptoms and AIDS-Related Mortality Among a Multisite Cohort of HIV-Positive Women
Cook, J. Α., Grey, D. D., Burke-Miller, J. K., Cohen, M. H., Gurtman, A., Richardson, J. L., Wilson, T. E., Young, M., & Hessol, N. A. (2004) · American Journal of Public Health · doi:10.2105/ajph.94.7.1133 · Cited by 396 · see citing works
Cooper, P. J., & Murray, L. (1998) · BMJ · doi:10.1136/bmj.316.7148.1884 · Cited by 334 · see citing works
Depressed mothers and infants: Failure to form dyadic states of consciousness.
Tronick, E. Z., & Weinberg, M. K. (1997) · Cited by 322 · see citing works
The Mother–Infant Relationship and Infant Attachment in a South African Peri-Urban Settlement
Tomlinson, M., Cooper, P., & Murray, L. (2005) · Child Development · doi:10.1111/j.1467-8624.2005.00896.x · Cited by 254 · see citing works
Guédeney, A., & Fermanian, J. (2001) · Infant Mental Health Journal · doi:10.1002/imhj.1018 · Cited by 222 · see citing works
Postnatal depression across countries and cultures: a qualitative study
Oates, M. R., Cox, J., Neema, S., Asten, P., Glangeaud-Freudenthal, N. M.-C., Figueiredo, B., Gorman, L., Hacking, S., Hirst, E., Kammerer, M. H., et al. (2004) · The British Journal of Psychiatry · doi:10.1192/bjp.184.46.s10 · Cited by 217 · see citing works
The impact of postpartum depression on child development
Murray, L., & Cooper, P. (1996) · International Review of Psychiatry · doi:10.3109/09540269609037817 · Cited by 214 · see citing works
Rahman, A., Harrington, R., & Bunn, J. (2002) · Child: Care, Health and Development · doi:10.1046/j.1365-2214.2002.00239.x · Cited by 148 · see citing works
Post‐partum depression and infant growth in a South African peri‐urban settlement
Tomlinson, M., Cooper, P. J., Stein, A., Swartz, L., & Molteno, C. (2006) · Child: Care, Health and Development · doi:10.1111/j.1365-2214.2006.00598.x · Cited by 113 · see citing works
Sustained withdrawal behavior in clinic-referred and nonreferred infants
Dollberg, D. G., Feldman, R., Keren, M., & Guédeney, A. (2006) · Infant Mental Health Journal · doi:10.1002/imhj.20093 · Cited by 83 · see citing works
Long term developmental impact of social withdrawal in infants
Milne, L. C., Greenway, P., Guédeney, A., et al. (2009) · Infant Behavior and Development · doi:10.1016/j.infbeh.2008.12.006 · Cited by 74 · see citing works
Infants’ social withdrawal and parents’ mental health
Mäntymaa, M., Puura, K., Luoma, I., Kaukonen, P., Salmelin, R. K., & Tamminen, T. (2008) · Infant Behavior and Development · doi:10.1016/j.infbeh.2008.07.005 · Cited by 62 · see citing works
Assessing the social behavior of infants: Use of the ADBB Scale and relationship to mother's mood
Matthey, S., Guédeney, A., Starakis, N., & Barnett, B. E. W. (2005) · Infant Mental Health Journal · doi:10.1002/imhj.20061 · Cited by 61 · see citing works
de Bruin, G. P., Swartz, L. M., Tomlinson, M., Cooper, P., & Molteno, C. D. (2004) · South African Journal of Psychology · doi:10.1177/008124630403400107 · Cited by 61 · see citing works
Attachment Disorders of Infancy
Zeanah, C. H., Boris, N. W., & Lieberman, A. F. (2000) · Springer eBooks · doi:10.1007/978-1-4615-4163-9_16 · Cited by 58 · see citing works
Screening for risk factors of relational withdrawal behaviour in infants aged 14–18 months
Guédeney, A., Foucault, C., Bougen, E., Larroque, B., & Mentré, F. (2007) · European Psychiatry · doi:10.1016/j.eurpsy.2007.07.008 · Cited by 56 · see citing works
Prevalence of depressive symptoms in late pregnancy and postpartum
Josefsson, A., Berg, G., Nordin, C., et al. (2001) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1080/j.1600-0412.2001.080003251.x · Cited by 47 · see citing works
Cho, J., Holditch‐Davis, D., & Miles, M. S. (2008) · Journal of Obstetric, Gynecologic & Neonatal Nursing · doi:10.1111/j.1552-6909.2007.00206.x · Cited by 45 · see citing works
Management of postnatal depression
Musters, C., McDonald, E., & Jones, I. R. (2008) · BMJ · doi:10.1136/bmj.a736 · Cited by 41 · see citing works
The Relationship of Maternal and Child HIV Infection to Security of Attachment Among Ugandan Infants
Peterson, N. J., Drotar, D., OLNESS, K. N., Guay, L. A., & Kiziri‐Mayengo, R. (2001) · Child Psychiatry & Human Development · doi:10.1023/a:1017581412328 · Cited by 36 · see citing works
Kwashiorkor, depression, and attachment disorders
Guédeney, A. (1995) · The Lancet · doi:10.1016/s0140-6736(95)91890-6 · Cited by 21 · see citing works
Rambaldini, G. (2003) · BMJ Evidence-Based Medicine · doi:10.1136/ebm.8.1.7 · Cited by 20 · see citing works
Moderately dysphoric mothers behave more positively with their infants after completing the BDI
Raag, T., Malphurs, J. E., Field, T. M., Peláez, M., Martinez, A., Pickens, J. N., Bendell, D., & Yando, R. (1997) · Infant Mental Health Journal · doi:10.1002/(sici)1097-0355(199724)18:4 · Cited by 8 · see citing works
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Stein, A., Pearson, R. M., Goodman, S. H., Rapa, E., Rahman, A., McCallum, M., Howard, L. M., & Pariante, C. M. (2014) · The Lancet · doi:10.1016/s0140-6736(14)61277-0 · Cited by 2,166 · see citing works
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Slomian, J., Honvo, G., Emonts, P., Reginster, J.-Y., & Bruyère, O. (2019) · Women's Health · doi:10.1177/1745506519844044 · Cited by 1,496 · see citing works
- Authors
- Hartley, C., Pretorius, K., Mohamed, A., Laughton, B., Madhi, S., Cotton, M. F., Steyn, B., & Seedat, S.
- Affiliations
- Stellenbosch University (ZA)
- University of the Witwatersrand (ZA)
- Corresponding author
- Seedat, S.
- Venue
- Psychology, Health & Medicine
- Publisher
- Informa UK Limited
- Published
- 2010-05
- Volume
- 15
- Issue
- 3
- Pages
- 278-287
- ISSN
- 1354-8506 (ISSN-L)
- 1465-3966
- OpenAlex
- W2040069720
- Cited by
- 43
- References
- 34
- Citations by year
- 2025: 1 · 2023: 2 · 2022: 1 · 2021: 2 · 2020: 3 · 2019: 3 · 2018: 4 · 2017: 2 · 2016: 4 · 2015: 2 · 2014: 5 · 2013: 12 · 2012: 1
- FWCI
- 4.44
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychology Health & Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Medical Research Council
- National Institute of Allergy and Infectious Diseases (U19 AI53217, U19AI053217)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Development and Preterm Care
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Keywords
- postpartum depression, HIV-positive mothers, mother-infant dyads, mother-child interaction, infant social behavior, failure to thrive, neurodevelopmental outcomes, behavioral effects
- MeSH terms
- Adolescent, Adult, Cross-Sectional Studies, Female, Humans, Infant, Middle Aged, Mother-Child Relations, Social Isolation, HIV Infections, Infant Behavior, Depression, Postpartum, Young Adult
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