Pregnancy and perinatal outcomes according to surgery to conception interval and gestational weight gain in women with previous gastric bypass
Abstract
OBJECTIVE: To compare perinatal and pregnancy outcomes including adherence to the Institute of Medicine's (IOM) recommendations for gestational weight gain (GWG) in pregnant women with conception <18 months (early group) compared to ≥18 months following gastric bypass (late group). METHODS: Retrospective cohort study comprising 71 women with gastric bypass and a singleton pregnancy presenting at Odense University Hospital, November 2007-October 2013. Data were extracted from medical records and laboratory systems. The primary outcomes were timing of pregnancy and adherence to the IOM's recommendations for GWG. Secondary outcomes were birthweight, preterm delivery, cesarean section (CS), iron deficiency and post partum hemorrhage (PPH). RESULTS: Forty-three (61%) women conceived less than 18 months after gastric bypass surgery. Women in the late group had a significantly higher risk of requiring CS or receiving intravenous iron supplementation compared to the early group (57% versus 30%, p = 0.03 and 29% versus 7%, p = 0.02, respectively). Early conception was not significantly associated with insufficient GWG, preterm delivery or birthweight. Among 54 women with information on GWG, only 13 (24%) had an appropriate GWG. CONCLUSION: The majority of pregnant women with gastric bypass did not fulfill guidelines for GWG; however, this study could not support the recommendation to postpone pregnancy.
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Delaying pregnancy after bariatric surgery was associated with a trend towards lower odds for admission in the neonatal intensive care unit (OR 0.73, 95% CI 0.45 to 1.18).
“Delaying pregnancy was associated with a trend towards lower odds for admission in the neonatal intensive care unit (OR 0.73, 95% 0.45 to 1.18).”
From Clinical practice guidelines of the European Association for Endoscopic Surgery (EAES) on bariatric surgery: update 2020 endorsed by IFSO-EC, EASO and ESPCOP (2020) · cites this paper as [137]
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- Authors
- Stentebjerg, L. L., Andersen, L. L. T., Renault, K., Støving, R. K., & Jensen, D. M.
- Affiliations
- Odense University Hospital (DK)
- Corresponding author
- Stentebjerg, Louise Laage
- Venue
- The Journal of Maternal-Fetal & Neonatal Medicine
- Publisher
- Informa UK Limited
- Published
- 2016-07-17
- Volume
- 30
- Issue
- 10
- Pages
- 1182-1188
- ISSN
- 1476-4954 (ISSN-L)
- 1476-7058
- OpenAlex
- W2502698246
- Cited by
- 60
- References
- 23
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 3 · 2023: 11 · 2022: 9 · 2021: 6 · 2020: 9 · 2019: 8 · 2018: 5 · 2017: 3
- FWCI
- 5.91
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Maternal-Fetal & Neonatal Medicine (publishedVersion)
- PubMed (publishedVersion)
- University of Southern Denmark Research Portal (University of Southern Denmark) (submittedVersion)
- Funders
- Novo Nordisk
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
- Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
- Keywords
- gastric bypass, bariatric surgery, pregnancy outcomes, perinatal outcomes, gestational weight gain, conception timing, IOM weight gain guidelines, cesarean section, preterm birth, birth weight, iron deficiency, postpartum hemorrhage
- MeSH terms
- Adult, Birth Weight, Female, Gestational Age, Humans, Infant, Newborn, Obesity, Pregnancy, Pregnancy Complications, Pregnancy Outcome, Retrospective Studies, Time Factors, Gastric Bypass, Weight Gain, Body Mass Index, Logistic Models, Practice Guidelines as Topic
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