The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Anxiety and Quality of Life: Clinically Anxious Children With and Without Autism Spectrum Disorders Compared
Abstract
Comorbid anxiety disorders are common in children with autism spectrum disorders (ASD). However, studies comparing children with ASD to clinically anxious children are rare. This study investigated anxiety problems and health-related quality of life in children with high-functioning ASD and comorbid anxiety disorders (referred to as the ASD group), compared with children with anxiety disorders (referred to as the AD group). In total, 237 families participated; 115 children were in the ASD group (90 boys and 25 girls, M age = 11.37 years), and 122 children were in the AD group (62 boys and 60 girls, M age = 12.79 years). Anxiety disorders, anxiety symptoms, ASD-like symptoms, and health-related quality of life were assessed with the ADIS-C/P, SCARED-71, CSBQ, and EuroQol-5D, respectively. The number and types of anxiety disorders, as well as their severity, were similar in the ASD and AD groups; however, specific phobias were more common in the ASD group than in the AD group. As compared to the AD group, parents from the ASD group reported their children to have higher scores for total anxiety, social anxiety disorder, and panic disorder. More ASD-like behaviors and higher anxiety severity predicted a lower quality of life, irrespective of group. The results of this study support a highly similar phenotype of anxiety disorders in children with ASD; however, additional research is needed to examine the etiology and treatment effectiveness of anxiety disorders in children with ASD.
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In the citing paper
“Left untreated, these co-occuring conditions can have detrimental and potentially catastrophic impacts on ASD individuals and their families, such as decreased quality of life and increased stress, hindered educational and employment opportunities and increased risk of suicidality [12–21].”
From Pharmacological treatment in autism: a proposal for guidelines on common co-occurring psychiatric symptoms (2025) · cites this paper as [16]
In the citing paper
“Anxiety levels are positively associated with ASD severity [16], and severe anxiety in ASD youth has also been associated with aggression, decreased participation in social activities, and poor social relationships [95].”
From Pharmacological treatment in autism: a proposal for guidelines on common co-occurring psychiatric symptoms (2025) · cites this paper as [16]
In the citing paper
“In combination with aspects of the defining clinical characteristics of autism (difficulties in social interaction, communication and repetitive interests and behaviours; American Psychiatric Association, 2013), anxiety disorders negatively impact upon quality of life and are, therefore, an important target for interventions (van Steensel et al., 2012).”
From Examining a model of anxiety in autistic adults (2024) · cites this paper as van Steensel et al., 2012
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
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EuroQol: a new facility for the measurement of health-related quality of life
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Anxiety Disorders in Children and Adolescents with Autistic Spectrum Disorders: A Meta-Analysis
van Steensel, F. J. A., Bögels, S. M., & Perrin, S. (2011) · Clinical Child and Family Psychology Review · doi:10.1007/s10567-011-0097-0 · Cited by 1,463 · cited 1×
“A meta-analysis estimated that anxiety disorders occur in approximately 40% of youth with ASD (van Steensel, Bogels, & Perrin, 2011 ).”
BackgroundSelf-citationSILVERMAN, W. K., SAAVEDRA, L. M., & PINA, A. A. (2001) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200108000-00016 · Cited by 1,190
The Developmental Epidemiology of Anxiety Disorders: Phenomenology, Prevalence, and Comorbidity
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The Dutch tariff: results and arguments for an effective design for national EQ‐5D valuation studies
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Lecavalier, L. (2006) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0147-5 · Cited by 569
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Cited by
Sorted by citations
Lever, A. G., & Geurts, H. M. (2016) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-016-2722-8 · Cited by 572
“…et al. 2010; Garcı ´ a-Vil-lamisar and Rojahn 2015; Gotham et al. 2015; Holtmann et al. 2007; Jang and Matson 2015; Lai et al. 2011; Lugnega˚rd et al. 2011; Moss et al. 2015; Simonoff et al. 2008, 2013; Sterling et al. 2008; Tureck et al. 2014; van Steensel et al. 2012; Verheij et al. 2015).”
Autism, oxytocin and interoception
Quattrocki, E., & Friston, K. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.09.012 · Cited by 393
Autism spectrum disorder: advances in diagnosis and evaluation
Zwaigenbaum, L., & Penner, M. (2018) · BMJ · doi:10.1136/bmj.k1674 · Cited by 275
Anxiety Levels in Children with Autism Spectrum Disorder: A Meta-Analysis
van Steensel, F. J. A., & Heeman, E. J. (2017) · Journal of Child and Family Studies · doi:10.1007/s10826-017-0687-7 · Cited by 269
Jenkinson, R., Milne, E., & Thompson, A. (2020) · Autism · doi:10.1177/1362361320932437 · Cited by 205
“Anxiety amplifies difficulties with social functioning in this population and is predictive of poorer quality of life (van Steensel et al., 2012; White et al., 2009).”
Background
Metadata
- Authors
- van Steensel, F. J. A., Bögels, S. M., & Dirksen, C. D.
- Affiliations
- University of Amsterdam (NL)
- Maastricht University Medical Centre (NL)
- Corresponding author
- van Steensel, Francisca J. A.
- Venue
- Journal of Clinical Child & Adolescent Psychology
- Publisher
- Informa UK Limited
- Published
- 2012-11
- Volume
- 41
- Issue
- 6
- Pages
- 731-738
- ISSN
- 1537-4416 (ISSN-L)
- 1537-4424
- OpenAlex
- W2160162048
- Cited by
- 137
- References
- 29
- Citations by year
- 2026: 6 · 2025: 9 · 2024: 14 · 2023: 8 · 2022: 16 · 2021: 6 · 2020: 17 · 2019: 7 · 2018: 5 · 2017: 16 · 2016: 8 · 2015: 6 · 2014: 9 · 2013: 9 · 2012: 1
- FWCI
- 4.10
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical Child & Adolescent Psychology (publishedVersion)
- PubMed (publishedVersion)
- UvA-DARE (University of Amsterdam) (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Keywords
- autism spectrum disorder, anxiety disorders, comorbidities, health-related quality of life, children, social anxiety disorder, panic disorder, specific phobia, anxiety levels
- MeSH terms
- Anxiety Disorders, Child, Child Behavior, Child Development Disorders, Pervasive, Female, Health Status, Humans, Interpersonal Relations, Male, Quality of Life, Severity of Illness Index, Social Behavior, Comorbidity
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