Cited by 1,463Autism Spectrum Disorder ResearchChild and Adolescent Psychosocial and Emotional DevelopmentChild Nutrition and Feeding Issues

Anxiety Disorders in Children and Adolescents with Autistic Spectrum Disorders: A Meta-Analysis

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van Steensel, Francisca J. A., Bögels, Susan M., Perrin, Sean·2011·Clinical Child and Family Psychology Review

Abstract

There is considerable evidence that children and adolescents with autistic spectrum disorders (ASD) are at increased risk of anxiety and anxiety disorders. However, it is less clear which of the specific DSM-IV anxiety disorders occur most in this population. The present study used meta-analytic techniques to help clarify this issue. A systematic review of the literature identified 31 studies involving 2,121 young people (aged <18 years) with ASD, and where the presence of anxiety disorder was assessed using standardized questionnaires or diagnostic interviews. Across studies, 39.6% of young people with ASD had at least one comorbid DSM-IV anxiety disorder, the most frequent being specific phobia (29.8%) followed by OCD (17.4%) and social anxiety disorder (16.6%). Associations were found between the specific anxiety disorders and ASD subtype, age, IQ, and assessment method (questionnaire versus interview). Implications for the identification and treatment of anxiety in young people with ASD are discussed.

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Crossref · 10.1007/s10567-011-0097-0

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  • Specific phobia (29%), OCD (17.4%), and social anxiety disorder (16.6%) were the three most commonly observed anxiety disorders in ASD youth.

    “Specific phobia (29%), obsessive–compulsive disorder (OCD) (17.4%), and social anxiety disorder (16.6%) were the three most commonly observed anxiety disorders in ASD youth [94].”

    From Pharmacological treatment in autism: a proposal for guidelines on common co-occurring psychiatric symptoms (2025) · cites this paper as [94]

    The Abstract identifies specific phobia, OCD, and social anxiety disorder as the three most frequent anxiety disorders in young people with ASD, and gives 17.4% and 16.6% for the latter two. It reports specific phobia at 29.8%, not the cited 29%. (LLM, conf=0.88)

    Experimental — accuracy not yet measured
  • Approximately 20% of children under 6 years and 40% of children ages 6 to 18 years with ASD have one or more anxiety disorders.

    “Approximately 20% of children under 6 years and 40% of children ages 6 to 18 years with ASD have one or more anxiety disorders [45, 47].”

    From DINOSAUR: an integrated cognitive-behavioral treatment for anxiety in young children with ASD (2021) · cites this paper as [45]

    The Discussion (‘Prevalence of Anxiety Disorders in Children with ASD’; page unavailable) estimates anxiety or at least one anxiety disorder in nearly 40% of children and adolescents with ASD. It does not give that estimate specifically for ages 6–18 or report a 20% rate for children under 6. (LLM, conf=0.88)

    Experimental — accuracy not yet measured
  • 40%-50% of autistic individuals meet formal criteria for a co-occurring anxiety disorder.

    “Although prevalence estimates vary across studies, the current consensus is that 40%–50% of autistic individuals meet formal criteria for a co-occurring anxiety disorder (Buck et al., 2014; Van Steensel et al., 2011)”

    From Self-guided mindfulness and cognitive behavioural practices reduce anxiety in autistic adults: A pilot 8-month waitlist-controlled trial of widely available online tools. (2020) · cites this paper as Van Steensel et al., 2011

    The Abstract reports that 39.6% of young people under 18 with ASD had at least one comorbid DSM-IV anxiety disorder, supporting the approximate 40% figure. But the claim extends this estimate to autistic individuals of all ages, and the Method (Coding) says the analysis also included studies using clinical anxiety cutoffs rather than formal disorder criteria. The Discussion reports a 31.5%–50.0% range for a subset of studies, not a 40%–50% estimate for all autistic individuals. (LLM, conf=0.88)

    Experimental — accuracy not yet measured
  • Anxiety occurs commonly in individuals with ASD, with lifetime estimates as high as 35%.

    “Like ADHD, these other diagnoses are now recognized to occur commonly in individuals with ASD, including lifetime estimates for depression as high as 25% (Leyfer et al. 2006) and anxiety as high as 35% (van Steensel et al. 2011).”

    From Recent Advances in Autism Research as Reflected in DSM-5 Criteria for Autism Spectrum Disorder (2015) · cites this paper as van Steensel et al. 2011

    The Discussion (Prevalence of Anxiety Disorders in Children with ASD; page unavailable) says anxiety is common in children and adolescents with ASD, estimating nearly 40% with clinically elevated anxiety or at least one anxiety disorder. It does not identify this as a lifetime estimate of 35%, and its findings concern young people rather than individuals with ASD of all ages. (LLM, conf=0.88)

    Experimental — accuracy not yet measured
  • According to a meta-analysis, 39.6% of youth with ASD have at least one co-occurring anxiety disorder based on the DSM-IV criteria.

    “According to a meta-analysis, 39.6% of youth with ASD have at least one co-occurring anxiety disorder based on the DSM-IV criteria [71, 94].”

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Authors
van Steensel, F. J. A., Bögels, S. M., & Perrin, S.
Affiliations
  • University of Amsterdam (NL)
  • King's College London (GB)
Venue
Clinical Child and Family Psychology Review
Published
2011-07-07
Volume
14
Issue
3
Pages
302-317
ISSN
  • 1096-4037 (ISSN-L)
  • 1573-2827
OpenAlex
W2138006810
Cited by
1,463
References
104
Citations by year
2026: 147 · 2025: 105 · 2024: 94 · 2023: 109 · 2022: 134 · 2021: 137 · 2020: 138 · 2019: 112 · 2018: 107 · 2017: 94 · 2016: 83 · 2015: 70 · 2014: 59 · 2013: 52 · 2012: 21
FWCI
3.53
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
  • Clinical Child and Family Psychology Review (publishedVersion, cc-by-nc)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • UvA-DARE (University of Amsterdam) (submittedVersion, other-oa)
  • Research Portal (King's College London) (submittedVersion)
  • Lund University Publications (Lund University) (submittedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
  • Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
Keywords
autism spectrum disorder, anxiety disorders, comorbidities, children and adolescents, specific phobia, obsessive-compulsive disorder, social anxiety disorder, ASD subtypes, IQ
MeSH terms
Adolescent, Anxiety Disorders, Child, Child Development Disorders, Pervasive, Child, Preschool, Humans, Intelligence, Obsessive-Compulsive Disorder, Phobic Disorders, Comorbidity, Prevalence, Databases, Bibliographic

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