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Autophagy in Dictyostelium: Mechanisms, regulation and disease in a simple biomedical model
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TOLLIP-deficient mice tend to develop more severe atherosclerosis as well as neurological defects.
“Pathologically, TOLLIP-deficient mice tend to develop more severe atherosclerosis as well as neurological defects [628, 631].”
From Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 (2021) · cites this paper as [628]
Studies with mammalian immune cells indicate that TOLLIP is primarily responsible for the final step of autophagy, and facilitates fusion of lysosomes with autophagosomes, lipid droplets, or peroxisomes.
“Studies with mammalian immune cells indicate that TOLLIP is primarily responsible for the final step of autophagy, and facilitates the fusion of lysosomes with autophagosomes, lipid droplets, or peroxisomes [627] [628].”
From Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 (2021) · cites this paper as [628]
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Cites
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy · doi:10.1080/15548627.2015.1100356 · Cited by 5,894
Self-citationde Duve, C., & Wattiaux, R. (1966) · Annual Review of Physiology · doi:10.1146/annurev.ph.28.030166.002251 · Cited by 3,033 · cited 1×
“tron microscopy (TEM) studies of germinating spores in 1969,(10) shortly after Christian de Duve coined the term autophagy.(11) We have come a long way from these initial mor-”
BackgroundThe Role of Atg Proteins in Autophagosome Formation
Mizushima, N., Yoshimori, T., & Ohsumi, Y. (2011) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-092910-154005 · Cited by 2,978
Kimura, S., Noda, T., & Yoshimori, T. (2007) · Autophagy · doi:10.4161/auto.4451 · Cited by 2,278
The machinery of macroautophagy
Feng, Y., He, D., Yao, Z., & Klionsky, D. J. (2014) · Cell Research · doi:10.1038/cr.2013.168 · Cited by 2,083
Atg8: an autophagy-related ubiquitin-like protein family.
Shpilka, T., Weidberg, H., Pietrokovski, S., & Elazar, Z. (2011) · Genome biology · doi:10.1186/gb-2011-12-7-226 · Cited by 543 · cited 2×
“tion of further specialized functions in more complex animals.(70) Similarly, the Atg4 paralogs and the Atg16 paralog in the 2 Ubl conjugation systems may enable the fine-tuning of the activation of the different Atg8/LC3 family members.”
BackgroundSalmonellae interactions with host processes
LaRock, D. L., Chaudhary, A., & Miller, S. I. (2015) · Nature Reviews Microbiology · doi:10.1038/nrmicro3420 · Cited by 502
An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis
Mari, M., Griffith, J., Rieter, E., Krishnappa, L., Klionsky, D. J., & Reggiori, F. (2010) · Journal of Cell Biology · doi:10.1083/jcb.200912089 · Cited by 491
Biogenesis and Cargo Selectivity of Autophagosomes
Weidberg, H., Shvets, E., & Elazar, Z. (2011) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-052709-094552 · Cited by 466
Tresse, E., Salomons, F. A., Vesa, J., Bott, L. C., Kimonis, V., Yao, T.-P., Dantuma, N. P., & Taylor, J. P. (2010) · Autophagy · doi:10.4161/auto.6.2.11014 · Cited by 437
Huntingtin functions as a scaffold for selective macroautophagy
Rui, Y.-N., Xu, Z., Patel, B., Chen, Z., Chen, D., Tito, A., David, G., Sun, Y., Stimming, E. F., Bellen, H. J., et al. (2015) · Nature Cell Biology · doi:10.1038/ncb3101 · Cited by 423 · cited 1×
“In mammals, the HTT (huntingtin) protein also shares structural similarity to yeast Atg11 and, like RB1CC1, functions as a scaffold protein in the ULK1 complex.(53)”
BackgroundAtg9 Cycles Between Mitochondria and the Pre-Autophagosomal Structure in Yeasts
Reggiori, F., Shintani, T., Chong, H., Nair, U., & Klionsky, D. J. (2005) · Autophagy · doi:10.4161/auto.1.2.1840 · Cited by 266
Mestre, M. B., Fader, C. M., Sola, C., & Colombo, M. I. (2010) · Autophagy · doi:10.4161/auto.6.1.10698 · Cited by 152
Steele, S., Brunton, J., Ziehr, B., Taft-Benz, S., Moorman, N., & Kawula, T. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003562 · Cited by 123
Freeman, C., Seaman, M. N. J., & Reid, E. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2012.10.011 · Cited by 50
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy · doi:10.1080/15548627.2020.1797280 · Cited by 2,897
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Metadata
- Authors
- Mesquita, A., Cardenal-Muñoz, E., Dominguez, E., Muñoz-Braceras, S., Nuñez-Corcuera, B., Phillips, B. A., Tábara, L. C., Xiong, Q., Coria, R., Eichinger, L., Golstein, P., King, J. S., Soldati, T., Vincent, O., & Escalante, R.
- Affiliations
- Instituto de Investigaciones Biomédicas “Alberto Sols” (CSIC-UAM), Madrid, Spain
- Départment de Biochimie, Faculté des Sciences, Université de Genève, Switzerland
- Department of Biomedical Sciences, University of Sheffield, UK
- Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany
- Departamento de Genética Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, México
- Centre d'Immunologie de Marseille-Luminy, Aix Marseille Université UM2, Inserm, U1104, CNRS UMR7280, Marseille, France
- Venue
- Autophagy
- Publisher
- Informa UK Limited
- Published
- 2016-10-07
- Volume
- 13
- Issue
- 1
- Pages
- 24-40
- ISSN
- 1554-8627
- 1554-8635
- Cited by
- 84
- References
- 15
- Language
- en
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