The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
Sharing secrets: Oxytocin and trust in schizophrenia
Open accessAbstract
Previous studies indicated that oxytocin plays an important role in human trust, which is impaired in patients with severe mental disorders. In this study, we measured plasma oxytocin levels in patients with schizophrenia (n=50) and in healthy controls (n=50) after neutral and trust-related interpersonal interactions. Trust-related interactions were associated with increased oxytocin levels in controls. This effect was absent in patients with schizophrenia. Low oxytocin levels measured after trust-related interactions significantly predicted the negative symptoms of schizophrenia but were not related to positive symptoms, depression, anxiety, and neuropsychological functions. These results suggest that decreased trust-related oxytocin release is related to the negative symptoms and may be associated with social withdrawal, isolation, and flattened affect in schizophrenia.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Interestingly, early investigations provide some encouragement that oxytocin could prove a useful supplement to current treatment of both schizophrenia (Keri et al., 2008;Feifel et al., 2010) and drug addiction (You et al., 2001;Qi et al., 2009;Carson et al., 2010).”
From Oxytocin enhances pupil dilation and sensitivity to 'hidden' emotional expressions (2013) · cites this paper as Keri et al., 2008
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Positive and Negative Syndrome Scale (PANSS) for schizophrenia.
Kay, S. R., Fiszbein, A., & Opler, L. A. (1987) · Schizophrenia Bulletin · doi:10.1093/schbul/13.2.261 · Cited by 21,378
(1998) · The Journal of Clinical Psychiatry · Cited by 19,139
Journal of Clinical Psychiatry
(2018) · Journal of Clinical Psychiatry · doi:10.5505/kpd · Cited by 13,703
Oxytocin increases trust in humans
Kosfeld, M., Heinrichs, M., Zak, P. J., Fischbacher, U., & Fehr, E. (2005) · Nature · doi:10.1038/nature03701 · Cited by 3,690
DSM-IV: Diagnostic and Statistical Manual of Mental Disorders
Bell, C. C. (1994) · JAMA · doi:10.1001/jama.1994.03520100096046 · Cited by 2,608
Heinrichs, M., Baumgartner, T., Kirschbaum, C., & Ehlert, U. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00465-7 · Cited by 2,091
Oxytocin Modulates Neural Circuitry for Social Cognition and Fear in Humans
Kirsch, P., Esslinger, C., Chen, Q., Mier, D., Lis, S., Siddhanti, S., Gruppe, H., Mattay, V. S., Gallhofer, B., & Meyer-Lindenberg, A. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3984-05.2005 · Cited by 1,639
Neuroendocrine perspectives on social attachment and love
Sue Carter, C. (1998) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(98)00055-9 · Cited by 1,425
Oxytocin improves “mind-reading” in humans
Domes, G., Heinrichs, M., Michel, A., Berger, C., & Herpertz, S. C. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.07.015 · Cited by 1,298
Oxytocin shapes the neural circuitry of trust and trust adaptation in humans
Baumgartner, T., Heinrichs, M., Vonlanthen, A., Fischbacher, U., & Fehr, E. (2008) · Neuron · doi:10.1016/j.neuron.2008.04.009 · Cited by 1,258
Research works printed but not linked: 4
- Caldwell H. K., Molecular Psychiatry
- Green M. F., Schizophrenia Bulletin
- Juhász L. Z., 2003, Ideggyógyászati Szemle, 56, 303
- Mai J. K., 1993, Journal für Hirnforschung, 34, 133
Cited by
Sorted by citations
Items 101–166 of 166
Oxytocin and Social Cognitions in Schizophrenia: A Systematic Review
Bukovskaya, O., & Shmukler, A. B. (2015) · Psychiatric Quarterly · doi:10.1007/s11126-015-9407-x · Cited by 24
Hernández‐Díaz, Y., González‐Castro, T. B., Tovilla‐Zárate, C. A., López‐Narváez, M. L., Mendoza, A. D. G., Castillo-Ávila, R. G., Ramos-Méndez, M. Á., & Juárez‐Rojop, I. E. (2021) · Metabolic Brain Disease · doi:10.1007/s11011-021-00836-y · Cited by 21
Brain circuit dysfunction in a distinct subset of chronic psychotic patients
Goldman, M. B. (2014) · Schizophrenia Research · doi:10.1016/j.schres.2014.06.001 · Cited by 22
Montag, C., Schöner, J., Speck, L. G., Just, S. A., Stuke, F., Rentzsch, J., Gallinat, J., & Majić, T. (2020) · PLoS ONE · doi:10.1371/journal.pone.0231257 · Cited by 23
Bánki, L., Büki, A., Horváth, G., Kékesi, G., Kis, G., Somogyvári, F., Jancsó, G., Vécsei, L., Varga, E., & Tuboly, G. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2019.134561 · Cited by 20
The neuroanatomy of social trust predicts depression vulnerability
Fermin, A. S. R., Kiyonari, T., Matsumoto, Y., Takagishi, H., Li, Y., Kanai, R., Sakagami, M., Akaishi, R., Ichikawa, N., Takamura, M., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-20443-w · Cited by 21
Balıkçı, K., Aydın, O., Taş, C., & Danacı, A. E. (2017) · Psychiatry and Clinical Psychopharmacology · doi:10.1080/24750573.2017.1387405 · Cited by 17
Endogenous oxytocin and human social interactions: A systematic review and meta-analysis.
Burenkova, O. V., Dolgorukova, T. A., An, I., Kustova, T. A., Podturkin, A. A., Shurdova, E. M., Talantseva, O. I., Zhukova, M., & Grigorenko, E. L. (2023) · Psychological Bulletin · doi:10.1037/bul0000402 · Cited by 17
Linking childhood trauma to the psychopathology of schizophrenia: the role of oxytocin
Chen, Y.-J., Lu, M., Chiu, Y.-H., Chen, C., Santos, V. H. J., & Goh, K. K. (2024) · Schizophrenia · doi:10.1038/s41537-024-00433-9 · Cited by 19
Nakata, Y., Kanahara, N., Kimura, A., Niitsu, T., Komatsu, H., Oda, Y., Nakamura, M., Ishikawa, M., Hasegawa, T., Kamata, Y., et al. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.03.053 · Cited by 16
Marazziti, D., Diep, P.-T., Carter, C. S., & Carbone, M. G. (2022) · Current Medicinal Chemistry · doi:10.2174/0929867329666220727120646 · Cited by 16
Oxytocin and Schizophrenia Spectrum Disorders
Ettinger, U., Hurlemann, R., & Chan, R. C. K. (2017) · Current topics in behavioral neurosciences · doi:10.1007/7854_2017_27 · Cited by 17
Endogenous oxytocin response to film scenes of attachment and loss is pronounced in schizophrenia
Speck, L. G., Schöner, J., Bermpohl, F., Heinz, A., Gallinat, J., Majić, T., & Montag, C. (2018) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsy110 · Cited by 14
Psychological Dimensions Relevant to Motivation and Pleasure in Schizophrenia
Abram, S. V., Weittenhiller, L. P., Bertrand, C. E., McQuaid, J. R., Mathalon, D. H., Ford, J. M., & Fryer, S. L. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.827260 · Cited by 18
Tseng, H. C., Chi, M. H., Lee, L.-T., Tsai, H. C., Lee, I. H., Chen, K. C., Yang, Y. K., & Chen, P. S. (2014) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.12.011 · Cited by 14
Oxytocin/vasopressin-like neuropeptide signaling in insects
Muratspahić, E., Monjon, E., Duerrauer, L., Rogers, S. M., Cullen, D. A., Broeck, J. V., & Gruber, C. W. (2020) · Vitamins and hormones · doi:10.1016/bs.vh.2019.08.011 · Cited by 15
Lee, M. R., Wehring, H. J., McMahon, R. P., Liu, F., Linthicum, J., Buchanan, R. W., Strauss, G. P., Rubin, L. H., & Kelly, D. L. (2019) · Journal of Psychiatry and Brain Science · doi:10.20900/jpbs.20190001 · Cited by 14
A Meta-Analysis of Factors Influencing the Development of Human-Robot Trust
Hancock, P. A., Billings, D. R., Oleson, K. E., Jessie, Y. C., de Visser, E. J., & Parasuraman, R. (2011) · Cited by 14
Teachers’ Punishment Intensity and Student Observer Trust: A Moderated Mediation Model
Zhang, Z., & Qi, C. (2024) · Behavioral Sciences · doi:10.3390/bs14060471 · Cited by 13
The neurobiological impact of oxytocin in mental health disorders: a comprehensive review
Chaulagain, R. P., Shrestha, Y., Shrestha, H., Bhandari, R., & Gurung, P. (2025) · Annals of Medicine and Surgery · doi:10.1097/ms9.0000000000003015 · Cited by 15
Haram, M., Tesli, M., Dieset, I., Steen, N. E., Røssberg, J. I., Djurovic, S., Andreassen, O. A., & Melle, I. S. (2014) · Neuropsychobiology · doi:10.1159/000356965 · Cited by 14
Pedersen, C. A. (2014) · Brain Research · doi:10.1016/j.brainres.2014.01.050 · Cited by 11
Spilka, M. J., Keller, W. R., Buchanan, R. W., Gold, J. M., Koenig, J. I., & Strauss, G. P. (2022) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13421 · Cited by 13
Pek, T. M., Yazıcı, E., Güzel, D., Köse, E., Yazıcı, A. B., & Erol, A. (2019) · Psychiatry and Clinical Psychopharmacology · doi:10.1080/24750573.2019.1653149 · Cited by 11
Exploring a Possible Interplay between Schizophrenia, Oxytocin, and Estrogens: A Narrative Review
Papadea, D., Dalla, C., & Tata, D. Α. (2023) · Brain Sciences · doi:10.3390/brainsci13030461 · Cited by 12
Peripheral Oxytocin Predicts Higher-Level Social Cognition in Men Regardless of Empathy Quotient
Deuse, L., Wudarczyk, O. A., Rademacher, L., Kaleta, P., Karges, W., Kacheva, S., Gründer, G., & Lammertz, S. E. (2018) · Pharmacopsychiatry · doi:10.1055/a-0590-4850 · Cited by 11
Approaches to Improve the Quantitation of Oxytocin in Human Serum by Mass Spectrometry
Hering, A., Jieu, B., Jones, A., & Muttenthaler, M. (2022) · Frontiers in Chemistry · doi:10.3389/fchem.2022.889154 · Cited by 9
Trust and psychosis: a systematic review and meta-analysis
Prasannakumar, A., Kumar, V., & Rao, N. P. (2022) · Psychological Medicine · doi:10.1017/s0033291722002562 · Cited by 8
Judging Strangers’ Trustworthiness is Associated with Theory of Mind Skills
Prévost, M., Brodeur, M. B., Onishi, K. H., Lepage, M., & Gold, I. (2015) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2015.00052 · Cited by 9
Empathy as a Concept from Bench to Bedside: A Translational Challenge
Uysal, N., Çamsarı, U. M., Ateş, M., Kandiş, S., Karakılıç, A., & Camsari, G. B. (2019) · Nöro Psikiyatri Arşivi · doi:10.29399/npa.23457 · Cited by 8
Psychoendocrinologie sociale de l’ocytocine : revue d’une littérature en pleine expansion
Lane, A., Luminet, O., & Mikolajczak, M. (2013) · L’Année psychologique · doi:10.4074/s0003503313002066 · Cited by 14
An exploration of blood-based biomarkers of negative symptoms of psychosis in men
Rodrigues, A., Santos, H. C., Ferreira, S., Diogo, V. S., Costa, M. A. D. S., Brissos, S., Marques, J. G., & Prata, D. P. (2024) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2024.06.050 · Cited by 5
Ali, E. H. A., Hassan, M. K., Abbas, O., E.Elmalahy, H., & Almaaty, A. A. (2020) · African Journal of Biological Sciences · doi:10.21608/ajbs.2020.133010 · Cited by 6
Charting the neuroscience of interpersonal trust: A bibliographic literature review
Wu, Y. H., & Krüeger, F. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105930 · Cited by 6
The Role of Lactylation in Mental Illness: Emphasis on Microglia
Sfera, A., Klein, C. A., Anton, J. J., Kozlakidis, Z., & Andronescu, C. V. (2023) · Neuroglia · doi:10.3390/neuroglia4020009 · Cited by 5
Tse, W. S., Wong, A. S. W., Chan, F., Pang, A. H. T., Bond, A. J., & Chan, C. K. R. (2016) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12382 · Cited by 5
Oxytocin in Prevention of Schizophrenia
Tadjibaev, A. (2013) · International Journal of Prevention and Treatment of Substance Use Disorders · Cited by 4
Lemmers-Jansen, I. L. J., & Fett, A.-K. J. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108770880.022 · Cited by 4
Trust – a Subject for Social Neuroscience?
Schipper, M., & Petermann, F. (2011) · Zeitschrift für Neuropsychologie · doi:10.1024/1016-264x/a000053 · Cited by 4
Neurobiology of interpersonal trust
Nowakowski, M. E., Vaillancourt, T., & Schmidt, L. A. (2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511750946.003 · Cited by 4
Heinrichs, M., Chen, F. S., & Domes, G. (2012) · Wiley eBooks · doi:10.1002/9781119945901.ch8 · Cited by 4
Rizavi, H. S., Chase, K. A., Liu, C., Gavin, H. E., Rosen, C., Xia, C., Guidotti, A., & Sharma, R. P. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.1006109 · Cited by 3
Sozialpsychiatrie und Neurobiologie
Kawohl, W., Wyss, C., Roser, P., Brüne, M., Wulf Rössler, A., & Juckel, G. (2016) · Der Nervenarzt · doi:10.1007/s00115-016-0179-9 · Cited by 2
Yılmaz, S. A., Öner, P., Taşçı, G., & Kaya, Ş. (2022) · Journal of Forensic Psychiatry and Psychology · doi:10.1080/14789949.2022.2156378 · Cited by 4
The Interplay of Oxytocin and Attachment in Schizophrenic Patients: An fMRI Study
Hennig-Fast, K., Meissner, D., Steuwe, C., Dehning, S., Blautzik, J., Eilert, D. W., Zill, P., Müller, N., Meindl, T., Reiser, M., et al. (2023) · Brain Science · doi:10.3390/brainsci13081125 · Cited by 2
In brains we trust: How neuroeconomists stylize trust, the brain, and the social world
Klaassen, P. (2014) · UvA-DARE (University of Amsterdam) · Cited by 2
Prepulse Inhibition of the Startle Reflex in Forebrain Oxytocin Receptor Knockout Mice
Swonger, J. M. (2011) · OhioLink ETD Center (Ohio Library and Information Network) · Cited by 1
Experimental Usage of Oxytocin to Combat Deficits in Social Cognition in Schizophrenia
Taş, C., Brown, E. C., Gonzalez, C., & Brüne, M. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-405172-0.00018-1 · Cited by 1
A Neuroergonomic Perspective on Human-Automation Etiquette and Trust
de Visser, E. J., & Parasuraman, R. (2010) · Advances in human factors and ergonomics series · doi:10.1201/ebk1439835012-c21 · Cited by 1
The role of oxytocin in the pathogenesis and treatment of schizophrenia
Jusiak, K., Brudkowska, Ż., Gołębiowska, M., Morylowska-Topolska, J., Gołębiowska, B., Próchnicki, M., Próchnicka, A., & Karakuła‐Juchnowicz, H. (2017) · Current Problems of Psychiatry · doi:10.1515/cpp-2017-0023 · Cited by 1
Kanahara, N., Nakamura, M., Shiko, Y., Kawasaki, Y., & Iyo, M. (2022) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2022.103157 · Cited by 1
Hernández‐Díaz, Y., González‐Castro, T. B., Tovilla‐Zárate, C. A., López‐Narváez, M. L., Mendoza, A. D. G., Castillo-Ávila, R. G., Ramos-Méndez, M. Á., & Juárez‐Rojop, I. E. (2021) · Research Square · doi:10.21203/rs.3.rs-260914/v1 · Cited by 1
Psychosoziale Effekte von Oxytocin und Vasopressin und ihre therapeutischen Anwendungsmöglichkeiten
Thienel, M., & Hallschmid, M. (2012) · Zeitschrift für Medizinische Psychologie · doi:10.3233/zmp-2012-210005
The effects of oxytocin on social behaviour: the influence of context and individual differences
Daughters, K. (2016) · ORCA Online Research @Cardiff (Cardiff University)
The relationship between oxytocin pathway genes and personality traits and psychosis characteristics
Haram, M. (2017) · NORA - Norwegian Open Research Archives
Luckhaus, C., Juckel, G., & Hurlemann, R. (2018) · Der Nervenarzt · doi:10.1007/s00115-018-0615-0
Oxytocin and Human Trust Behavior
张, 美. (2019) · Advances in Psychology · doi:10.12677/ap.2019.93058
The Other Face of Oxytocin : Role of Oxytocin in Neuropsychiatric Disorders
Chetcuti, S., Sammut, E., Sammut, M., & Calleja‐Agius, J. (2019) · doi:10.24946/ijpls.20.18.00.00.040605
Luckhaus, C., Juckel, G., & Hurlemann, R. (2019) · Der Nervenarzt
Neuropathological Level of Trust
Krüeger, F. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108770880.021
Krüeger, F. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108770880.017
Lee, M. R., Veerareddy, A., & Krüeger, F. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108770880.019
No Change in Serum Oxytocin Concentrations in Patients with Treatment-Resistant SchizophreniaPreprint
Kanahara, N., Nakamura, M., Shiko, Y., Kawasaki, Y., & Iyo, M. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3960598
Oxytocin, Social Interactions and Coping: Implications for Depression
McInnis, O. A. (2016) · Carleton University's Institutional Repository (MacOdrum Library, Carleton University) · doi:10.22215/etd/2016-11454
Influence of Attachment Behavior in Psychosis
Kim, Y. (2022) · Korean Journal of Schizophrenia Research · doi:10.16946/kjsr.2022.25.2.23
Karakulak, Ş. I., Bulut, S. D., Karadağ, H., & Kocer, Z. A. (2026) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2026.02.013 · Cited by 1
Metadata
- Authors
- Kéri, S., Kiss, I., & Kelemen, O.
- Affiliations
- Semmelweis University (HU)
- b Bács-Kiskun County Hospital , Kecskemét, Hungary
- Corresponding author
- Kéri, Szabolcs
- ORCID
- Kéri, Szabolcs
- Venue
- Social Neuroscience
- Publisher
- Informa UK Limited
- Published
- 2009-06-25
- Volume
- 4
- Issue
- 4
- Pages
- 287-293
- ISSN
- 1747-0919 (ISSN-L)
- 1747-0927
- OpenAlex
- W2010808031
- Cited by
- 167
- References
- 41
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 5 · 2023: 4 · 2022: 14 · 2021: 11 · 2020: 7 · 2019: 10 · 2018: 7 · 2017: 8 · 2016: 11 · 2015: 12 · 2014: 16 · 2013: 23 · 2012: 8
- FWCI
- 12.44
- Type
- journal article
- Language
- en
- Open access
- Licence
- other-oa
- Locations
- Social Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- SZTE Publicatio Repozitórium (University of Szeged) (acceptedVersion, other-oa)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- oxytocin, trust, schizophrenia, plasma oxytocin, interpersonal interaction, negative symptoms, social withdrawal, social cognition
- MeSH terms
- Female, Humans, Interpersonal Relations, Male, Middle Aged, Neuropsychological Tests, Oxytocin, Schizophrenia, Schizophrenic Psychology, Trust
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
