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Sharing secrets: Oxytocin and trust in schizophrenia
Open accessAbstract
Previous studies indicated that oxytocin plays an important role in human trust, which is impaired in patients with severe mental disorders. In this study, we measured plasma oxytocin levels in patients with schizophrenia (n=50) and in healthy controls (n=50) after neutral and trust-related interpersonal interactions. Trust-related interactions were associated with increased oxytocin levels in controls. This effect was absent in patients with schizophrenia. Low oxytocin levels measured after trust-related interactions significantly predicted the negative symptoms of schizophrenia but were not related to positive symptoms, depression, anxiety, and neuropsychological functions. These results suggest that decreased trust-related oxytocin release is related to the negative symptoms and may be associated with social withdrawal, isolation, and flattened affect in schizophrenia.
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“Interestingly, early investigations provide some encouragement that oxytocin could prove a useful supplement to current treatment of both schizophrenia (Keri et al., 2008;Feifel et al., 2010) and drug addiction (You et al., 2001;Qi et al., 2009;Carson et al., 2010).”
From Oxytocin enhances pupil dilation and sensitivity to 'hidden' emotional expressions (2013) · cites this paper as Keri et al., 2008
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Cites
The Positive and Negative Syndrome Scale (PANSS) for schizophrenia.
Kay, S. R., Fiszbein, A., & Opler, L. A. (1987) · Schizophrenia Bulletin · doi:10.1093/schbul/13.2.261 · Cited by 21,378
(1998) · The Journal of Clinical Psychiatry · Cited by 19,139
Journal of Clinical Psychiatry
(2018) · Journal of Clinical Psychiatry · doi:10.5505/kpd · Cited by 13,703
Oxytocin increases trust in humans
Kosfeld, M., Heinrichs, M., Zak, P. J., Fischbacher, U., & Fehr, E. (2005) · Nature · doi:10.1038/nature03701 · Cited by 3,690
DSM-IV: Diagnostic and Statistical Manual of Mental Disorders
Bell, C. C. (1994) · JAMA · doi:10.1001/jama.1994.03520100096046 · Cited by 2,608
Heinrichs, M., Baumgartner, T., Kirschbaum, C., & Ehlert, U. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00465-7 · Cited by 2,091
Oxytocin Modulates Neural Circuitry for Social Cognition and Fear in Humans
Kirsch, P., Esslinger, C., Chen, Q., Mier, D., Lis, S., Siddhanti, S., Gruppe, H., Mattay, V. S., Gallhofer, B., & Meyer-Lindenberg, A. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3984-05.2005 · Cited by 1,639
Neuroendocrine perspectives on social attachment and love
Sue Carter, C. (1998) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(98)00055-9 · Cited by 1,425
Oxytocin improves “mind-reading” in humans
Domes, G., Heinrichs, M., Michel, A., Berger, C., & Herpertz, S. C. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.07.015 · Cited by 1,298
Oxytocin shapes the neural circuitry of trust and trust adaptation in humans
Baumgartner, T., Heinrichs, M., Vonlanthen, A., Fischbacher, U., & Fehr, E. (2008) · Neuron · doi:10.1016/j.neuron.2008.04.009 · Cited by 1,258
Green, M. F., Penn, D. L., Bentall, R. P., Carpenter, W. T., Gäebel, W., Gur, R. C., Kring, A. M., Park, S., Silverstein, S. M., & HEINSSEN, R. K. (2008) · Schizophrenia Bulletin · doi:10.1093/schbul/sbm145 · Cited by 1,111
Landgraf, R., & Neumann, I. D. (2004) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2004.05.001 · Cited by 1,059
Oxytocin increases gaze to the eye region of human faces
Guastella, A. J., Mitchell, P. B., & Dadds, M. R. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.06.026 · Cited by 798
Social neuroeconomics: the neural circuitry of social preferences
Fehr, E., & Camerer, C. F. (2007) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2007.09.002 · Cited by 779
Oxytocin attenuates amygdala responses to emotional faces regardless of valence
Domes, G., Heinrichs, M., Gläscher, J., Büchel, C., Braus, D. F., & Herpertz, S. C. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.03.025 · Cited by 774 · cited 1×
“Oxytocin facilitates decoding of faces expressing complex mental states and social emotions (Domes et al., 2007), increases gaze to the eye regions of other people’s faces (Guastella, Mitchell, & Dadds, 2008), promotes trust and trustworthiness during interpersonal economic transactions (Kosfeld,…”
BackgroundStress and the hypothalamic pituitary adrenal axis in the developmental course of schizophrenia
Walker, E., Mittal, V., & Tessner, K. (2008) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.4.022007.141248 · Cited by 615
Oxytocin is associated with human trustworthiness
ZAK, P., KURZBAN, R., & MATZNER, W. (2005) · Hormones and Behavior · doi:10.1016/j.yhbeh.2005.07.009 · Cited by 595
Grewen, K. M., Girdler, S. S., Amico, J., & Light, K. C. (2005) · Psychosomatic Medicine · doi:10.1097/01.psy.0000170341.88395.47 · Cited by 513 · cited 2×
“Some authors suggest that oxytocin is an ‘‘anti-stress’’ or ‘‘anti-anxiety’’ hormone (e.g. Grewen et al., 2005; Kirsch et al., 2005; Tops et al., 2007).”
Gold, J. M., Queern, C. A., Iannone, V. N., & Buchanan, R. W. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.12.1944 · Cited by 327
Attachment, aggression and affiliation: the role of oxytocin in female social behavior
Campbell, A. (2008) · Biological Psychology · doi:10.1016/j.biopsycho.2007.09.001 · Cited by 269
Bernstein, H., Stanarius, A., Baumann, B., Henning, H. J., Krell, D., Dános, P., Falkai, P., & Bogerts, B. (1998) · Neuroscience · doi:10.1016/s0306-4522(97)00461-2 · Cited by 223
Goldman, M. B., Marlow-O’Connor, M., Torres, I. J., & Carter, C. S. (2007) · Schizophrenia Research · doi:10.1016/j.schres.2007.09.019 · Cited by 216
Anxiety, cortisol, and attachment predict plasma oxytocin
Tops, M., Van Peer, J. M., Korf, J., Wijers, A. A., & Tucker, D. M. (2007) · Psychophysiology · doi:10.1111/j.1469-8986.2007.00510.x · Cited by 197
Hobart, M., Goldberg, R. W., Bartko, J. J., & Gold, J. M. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.12.1951 · Cited by 181
Vasopressin-oxytocin in cerebrospinal fluid of schizophrenic patients and normal controls
Beckmann, H., Lang, R. E., & Gattaz, W. F. (1985) · Psychoneuroendocrinology · doi:10.1016/0306-4530(85)90056-3 · Cited by 138
Wilk, C. M. (2003) · Schizophrenia Research · doi:10.1016/j.schres.2003.10.009 · Cited by 131
Oxytocin modulates psychotomimetic-induced deficits in sensorimotor gating
Feifel, D., & Reza, T. L. (1999) · Psychopharmacology · doi:10.1007/s002130050811 · Cited by 121
Stress and psychosis: Towards the development of new models of investigation
Phillips, L., Francey, S. M., Edwards, J., & McMurray, N. E. (2006) · Clinical Psychology Review · doi:10.1016/j.cpr.2006.10.003 · Cited by 113
Oxytocin as a natural antipsychotic: a study using oxytocin knockout mice
Caldwell, H. K., Stephens, S. L., & Young, W. S. (2008) · Molecular Psychiatry · doi:10.1038/sj.mp.4002150 · Cited by 108
The Role of Oxytocin in Neuropsychiatric Disorders
Marazziti, D., & Dell’Osso, M. C. (2008) · Current Medicinal Chemistry · doi:10.2174/092986708783885291 · Cited by 99
Cerebrospinal fluid neurophysins in affective illness and in schizophrenia
Linkowski, P., Geenen, V. G., Kerkhofs, M., Mendlewicz, J., & Legros, J. J. (1984) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/bf00461555 · Cited by 89
Studies in the relationship between depressive disorders and anxiety states
Mountjoy, C. Q., & Roth, M. (1982) · Journal of Affective Disorders · doi:10.1016/0165-0327(82)90043-x · Cited by 88
Glovinsky, D., Kalogeras, K. T., Kirch, D. G., Suddath, R. L., & Wyatt, R. (1994) · Schizophrenia Research · doi:10.1016/0920-9964(94)90021-3 · Cited by 84
Legros, J. J., GAZZOTTI, C., Carvelli, T., Franchimont, P., Timsit-Berthier, M., von Frenckell, R., & Ansseau, M. (1992) · Psychoneuroendocrinology · doi:10.1016/0306-4530(92)90019-4 · Cited by 69
Jk, M., Berger, K., & Mv, S. (1993) · PubMed · Cited by 64
Ultimatum bargaining behavior of people affected by schizophrenia
Agay, N., Kron, S., Carmel, Z., Mendlovic, S., & Levkovitz, Y. (2007) · Psychiatry Research · doi:10.1016/j.psychres.2006.03.026 · Cited by 56
Is Oxytocin an Anti-Schizophrenic Hormone?
Bujanow, W. (1974) · Canadian Psychiatric Association Journal · doi:10.1177/070674377401900323 · Cited by 45
RBANS neuropsychological profiles within schizophrenia samples recruited from non-clinical settings
Loughland, C. M., Lewin, T. J., Carr, V. J., Sheedy, J., & Harris, A. W. F. (2006) · Schizophrenia Research · doi:10.1016/j.schres.2006.08.022 · Cited by 42
Impaired strategic decision making in schizophrenia
Kim, H.-J., Lee, D., Shin, Y.-M., & Chey, J. (2007) · Brain Research · doi:10.1016/j.brainres.2007.08.049 · Cited by 37
The Role of Peptides in Treatment of Psychiatric Disorders
Holsboer, F. (2003) · Journal of neural transmission. Supplementum · doi:10.1007/978-3-7091-6020-6_2 · Cited by 35
Juhász, L. Z., Kemény, K., Linka, E., Sántha, J., & Bartkó, G. (2003) · PubMed · Cited by 16
Research works printed but not linked: 4
- Caldwell H. K., Molecular Psychiatry
- Green M. F., Schizophrenia Bulletin
- Juhász L. Z., 2003, Ideggyógyászati Szemle, 56, 303
- Mai J. K., 1993, Journal für Hirnforschung, 34, 133
Cited by
Sorted by citations
A Meta-Analysis of Factors Affecting Trust in Human-Robot Interaction
Hancock, P. A., Billings, D. R., Schaefer, K. E., Chen, J. Y. C., de Visser, E. J., & Parasuraman, R. (2011) · Human Factors: The Journal of the Human Factors and Ergonomics Society · doi:10.1177/0018720811417254 · Cited by 2,051
Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine
Meyer-Lindenberg, A., Domes, G., Kirsch, P., & Heinrichs, M. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3044 · Cited by 1,688
Oxytocin, vasopressin, and human social behavior
Heinrichs, M., von Dawans, B., & Domes, G. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.05.005 · Cited by 799
The Peptide That Binds: A Systematic Review of Oxytocin and its Prosocial Effects in Humans
MacDonald, K., & MacDonald, T. M. (2010) · Harvard Review of Psychiatry · doi:10.3109/10673220903523615 · Cited by 585
Oxytocin and the development of parenting in humans
Gordon, I., Zagoory-Sharon, O., Leckman, J. F., & Feldman, R. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.02.005 · Cited by 469
Metadata
- Authors
- Kéri, S., Kiss, I., & Kelemen, O.
- Affiliations
- Semmelweis University (HU)
- b Bács-Kiskun County Hospital , Kecskemét, Hungary
- Corresponding author
- Kéri, Szabolcs
- ORCID
- Kéri, Szabolcs
- Venue
- Social Neuroscience
- Publisher
- Informa UK Limited
- Published
- 2009-06-25
- Volume
- 4
- Issue
- 4
- Pages
- 287-293
- ISSN
- 1747-0919 (ISSN-L)
- 1747-0927
- OpenAlex
- W2010808031
- Cited by
- 167
- References
- 41
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 5 · 2023: 4 · 2022: 14 · 2021: 11 · 2020: 7 · 2019: 10 · 2018: 7 · 2017: 8 · 2016: 11 · 2015: 12 · 2014: 16 · 2013: 23 · 2012: 8
- FWCI
- 12.44
- Type
- journal article
- Language
- en
- Open access
- Licence
- other-oa
- Locations
- Social Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- SZTE Publicatio Repozitórium (University of Szeged) (acceptedVersion, other-oa)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- oxytocin, trust, schizophrenia, plasma oxytocin, interpersonal interaction, negative symptoms, social withdrawal, social cognition
- MeSH terms
- Female, Humans, Interpersonal Relations, Male, Middle Aged, Neuropsychological Tests, Oxytocin, Schizophrenia, Schizophrenic Psychology, Trust
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