The role of lamin B1 for the maintenance of nuclear structure and function

Chromosome territories, nuclear architecture and gene regulation in mammalian cells

Cremer, T. J., & Cremer, C. G. (2001) · Nature Reviews Genetics · doi:10.1038/35066075 · Cited by 2,339 · see citing works

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

Guelen, L., Pagie, L., Brasset, É., Meuleman, W. R. A., Faza, M. B., Talhout, W., Eussen, B. H. J., de Klein, A., Wessels, L. F. A., de Laat, W. L., et al. (2008) · Nature · doi:10.1038/nature06947 · Cited by 1,959 · see citing works

Chromosome TerritoriesPreprint

Cremer, T. J., & Cremer, M. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a003889 · Cited by 1,115 · see citing works

Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson–Gilford progeria syndrome

Goldman, R. D., Shumaker, D. K., Erdos, M. R., Eriksson, M., Goldman, A. E., Gordon, L. B., Gruenbaum, Y., Khuon, S., Mendez, M., Varga, R., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402943101 · Cited by 1,103 · see citing works

Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

Peric-Hupkes, D., Meuleman, W., Pagie, L., Bruggeman, S. W. M., Solovei, I., Brugman, W., Gräf, S., Flicek, P., Kerkhoven, R. M., van Lohuizen, M., et al. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.03.016 · Cited by 1,050 · see citing works

Lamin B1 loss is a senescence-associated biomarker

Freund, A., Laberge, R.-M., Demaria, M., & Campisi, J. (2012) · Molecular Biology of the Cell · doi:10.1091/mbc.e11-10-0884 · Cited by 1,046 · see citing works

Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatinPreprint

Dechat, T., Pfleghaar, K., Sengupta, K., Shimi, T., Shumaker, D. K., Solimando, L., & Goldman, R. D. (2008) · Genes & Development · doi:10.1101/gad.1652708 · Cited by 1,001 · see citing works

Identification of essential genes in cultured mammalian cells using small interfering RNAs

Harborth, J., Elbashir, S. M., Bechert, K., Tuschl, T., & Weber, K. K. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.24.4557 · Cited by 828 · see citing works

Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging

Shumaker, D. K., Dechat, T., Kohlmaier, A., Adam, S. A., Bozovsky, M. R., Erdos, M. R., Eriksson, M., Goldman, A. E., Khuon, S., Collins, F. S., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602569103 · Cited by 791 · see citing works

Transcriptional repression mediated by repositioning of genes to the nuclear lamina

Reddy, K. L., Zullo, J., Bertolino, E., & Singh, H. (2008) · Nature · doi:10.1038/nature06727 · Cited by 785 · see citing works

Nuclear lamins: building blocks of nuclear architecturePreprint

Goldman, R. D., Gruenbaum, Y., Moir, R. D., Shumaker, D. K., & Spann, T. P. (2002) · Genes & Development · doi:10.1101/gad.960502 · Cited by 587 · see citing works

Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells

Finlan, L. E., Sproul, D., Thomson, I., Boyle, S., Kerr, E. A., Perry, P., Ylstra, B., Chubb, J. R., & Bickmore, W. A. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000039 · Cited by 584 · see citing works

Nuclear Lamins: Laminopathies and Their Role in Premature Ageing

Broers, J. L. V., Ramaekers, F. C. S., Bonne, G., Yaou, R. B., & Hutchison, C. J. (2006) · Physiological Reviews · doi:10.1152/physrev.00047.2005 · Cited by 572 · see citing works

Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape

Shah, P. P., Donahue, G., Otte, G. L., Capell, B. C., Nelson, D. M., Cao, K., Aggarwala, V., Cruickshanks, H. A., Rai, T. S., McBryan, T., et al. (2013) · Genes & Development · doi:10.1101/gad.223834.113 · Cited by 550 · see citing works

The role of nuclear lamin B1 in cell proliferation and senescence

Shimi, T., Butin-Israeli, V., Adam, S. A., Hamanaka, R. B., Goldman, A. E., Lucas, C. A., Shumaker, D. K., Kosak, S. T., Chandel, N. S., & Goldman, R. D. (2011) · Genes & Development · doi:10.1101/gad.179515.111 · Cited by 547 · see citing works

The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcriptionPreprint

Shimi, T., Pfleghaar, K., Kojima, S.-I., Pack, C., Solovei, I. V., Goldman, A. E., Adam, S. A., Shumaker, D. K., Kinjo, M., Cremer, T. J., et al. (2008) · Genes & Development · doi:10.1101/gad.1735208 · Cited by 521 · see citing works

Nucleoporins Directly Stimulate Expression of Developmental and Cell-Cycle Genes Inside the Nucleoplasm

Kalverda, B., Pickersgill, H., Shloma, V. V., & Fornerod, M. W. J. (2010) · Cell · doi:10.1016/j.cell.2010.01.011 · Cited by 442 · see citing works

Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts

Cao, K., Blair, C. D., Faddah, D. A., Kieckhaefer, J. E., Olive, M., Erdos, M. R., Nabel, E. G., & Collins, F. S. (2011) · Journal of Clinical Investigation · doi:10.1172/jci43578 · Cited by 305 · see citing works

Disruption of Nuclear Lamin Organization Alters the Distribution of Replication Factors and Inhibits DNA Synthesis

Spann, T. P., Moir, R. D., Goldman, A. E., Stick, R., & Goldman, R. D. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.136.6.1201 · Cited by 289 · see citing works

Dynamic properties of nuclear lamins: lamin B is associated with sites of DNA replication.

Moir, R. D., Montag-Lowy, M., & Goldman, R. D. (1994) · The Journal of Cell Biology · doi:10.1083/jcb.125.6.1201 · Cited by 273 · see citing works

Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex.

Ludérus, M. E. E., van Steensel, B., Chong, L., Sibon, O. C. M., Cremers, F. F. M., & de Lange, T. (1996) · The Journal of Cell Biology · doi:10.1083/jcb.135.4.867 · Cited by 232 · see citing works

Oxidative stress induces an ATM‐independent senescence pathway through p38 MAPK‐mediated lamin B1 accumulation

Barascu, A., Le Chalony, C., Pennarun, G., Genet, D., Imam, N., Lopez, B., & Bertrand, P. (2012) · The EMBO Journal · doi:10.1038/emboj.2011.492 · Cited by 206 · see citing works

Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment

Columbaro, M., Capanni, C., Mattioli, E., Novelli, G., Parnaik, V. K., Squarzoni, S., Maraldi, N. M., & Lattanzi, G. (2005) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-005-5318-6 · Cited by 160 · see citing works

Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression

Malhas, A. N., Lee, C. F., Sanders, R., Saunders, N. J. S. G., & Vaux, D. J. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200607054 · Cited by 137 · see citing works

The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication

Shumaker, D. K., Solimando, L., Sengupta, K., Shimi, T., Adam, S. A., Grünwald, A., Strelkov, S. V., Aebi, U., Cardoso, M. C., & Goldman, R. D. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200708155 · Cited by 130 · see citing works

GST-lamin fusion proteins act as dominant negative mutants in Xenopusegg extract and reveal the function of the lamina in DNA replication

Ellis, D. J., Jenkins, H., Whitfield, W. G. F., et al. (1997) · Journal of Cell Science · doi:10.1242/jcs.110.20.2507 · Cited by 116 · see citing works

Dynamic associations of heterochromatin protein 1 with the nuclear envelope

Kourmouli, N., Theodoropoulos, P. A., Dialynas, G., Bakou, A., Politou, A. S., Cowell, I. G., Singh, P. B., & Georgatos, S. D. (2000) · The EMBO Journal · doi:10.1093/emboj/19.23.6558 · Cited by 111 · see citing works

The integrity of a lamin-B1-dependent nucleoskeleton is a fundamental determinant of RNA synthesis in human cells

Tang, C. W., Maya‐Mendoza, A., Martin, C., et al. (2008) · Journal of Cell Science · doi:10.1242/jcs.020982 · Cited by 109 · see citing works

Cdc6 ATPase Activity Regulates ORC·Cdc6 Stability and the Selection of Specific DNA Sequences as Origins of DNA Replication

Speck, C., & Stillman, B. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m700399200 · Cited by 106 · see citing works

Gene silencing at the nuclear periphery

Shaklai, S., Amariglio, N., Rechavi, G., & Simon, A. J. (2007) · FEBS Journal · doi:10.1111/j.1742-4658.2007.05697.x · Cited by 101 · see citing works

An absence of both lamin B1 and lamin B2 in keratinocytes has no effect on cell proliferation or the development of skin and hair

Yang, S. H., Chang, S. Y., Yin, L., Tu, Y., Hu, Y., Yoshinaga, Y., de Jong, P. J., Fong, L. G., & Young, S. G. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr266 · Cited by 90 · see citing works

A role for nuclear lamins in nuclear envelope assembly

Lopez‐Soler, R. I., Moir, R. D., Spann, T. P., Stick, R., & Goldman, R. D. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.200101025 · Cited by 83 · see citing works

HA95 and LAP2β mediate a novel chromatin–nuclear envelope interaction implicated in initiation of DNA replication

Martins, S., Eikvar, S., Furukawa, K., et al. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200210026 · Cited by 68 · see citing works

Loss of lamin B1 results in prolongation of S phase and decondensation of chromosome territories

Camps, J., Wangsa, D., Falke, M., et al. (2014) · The FASEB Journal · doi:10.1096/fj.14-250456 · Cited by 67 · see citing works

Are B-type lamins essential in all mammalian cells?

Yang, S. H., Jung, H.-J., Coffinier, C., Fong, L. G., & Young, S. G. (2011) · Nucleus · doi:10.4161/nucl.2.6.18085 · Cited by 47 · see citing works

CDC6 interaction with ATR regulates activation of a replication checkpoint in higher eukaryotic cells

Yoshida, K., Sugimoto, N., Iwahori, S., Yugawa, T., Narisawa‐Saito, M., Kiyono, T., & Fujita, M. (2010) · Journal of Cell Science · doi:10.1242/jcs.058693 · Cited by 47 · see citing works

Reciprocal knock-in mice to investigate the functional redundancy of lamin B1 and lamin B2

Lee, J. M., Tu, Y., Tatar, A., Wu, D. Y., Nobumori, C., Jung, H.-J., Yoshinaga, Y., Coffinier, C., de Jong, P. J., Fong, L. G., et al. (2014) · Molecular Biology of the Cell · doi:10.1091/mbc.e14-01-0683 · Cited by 28 · see citing works

DNA repair deficiency and senescence in concussed professional athletes involved in contact sports

Schwab, N., Grenier, K., & Hazrati, L.-N. (2019) · Acta Neuropathologica Communications · doi:10.1186/s40478-019-0822-3 · Cited by 47 · see citing works

From lamins to lamina: a structural perspective

Zwerger, M., & Medalia, O. (2013) · Histochemistry and Cell Biology · doi:10.1007/s00418-013-1104-y · Cited by 28 · see citing works

Structural and Mechanical Aberrations of the Nuclear Lamina in Disease

Stiekema, M., van Zandvoort, M. A. M. J., Ramaekers, F. C. S., & Broers, J. L. V. (2020) · Cells · doi:10.3390/cells9081884 · Cited by 54 · see citing works

Lamin dynamics

Moir, R. D., & Goldman, R. D. (1993) · Current Opinion in Cell Biology · doi:10.1016/0955-0674(93)90004-a · Cited by 50 · see citing works

Involvement of the Lamin Rod Domain in Heterotypic Lamin Interactions Important for Nuclear Organization

Schirmer, E. C., Guan, T., & Gerace, L. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.153.3.479 · Cited by 135 · see citing works

The nuclear lamins: flexibility in function

Burke, B. E., & Stewart, C. L. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3488 · Cited by 563 · see citing works