The DOI matches its Crossref record; 49 of the 50 references it cites were found in a registry or an index.
Cost-Effectiveness of Cognitive–Behavioural Therapy and Drug Interventions for Major Depression
Abstract
Objective Antidepressant drugs and cognitive-behavioural therapy (CBT) are effective treatment options for depression and are recommended by clinical practice guidelines. As part of the Assessing Cost-effectiveness -- Mental Health project we evaluate the available evidence on costs and benefits of CBT and drugs in the episodic and maintenance treatment of major depression. Method The cost-effectiveness is modelled from a health-care perspective as the cost per disability-adjusted life year. Interventions are targeted at people with major depression who currently seek care but receive non-evidence based treatment. Uncertainty in model inputs is tested using Monte Carlo simulation methods. Results All interventions for major depression examined have a favourable incremental cost-effectiveness ratio under Australian health service conditions. Bibliotherapy, group CBT, individual CBT by a psychologist on a public salary and tricyclic antidepressants (TCAs) are very cost-effective treatment options falling below 10,000 Australian dollars per disability-adjusted life year (DALY) even when taking the upper limit of the uncertainty interval into account. Maintenance treatment with selective serotonin re-uptake inhibitors (SSRIs) is the most expensive option (ranging from 17,000 Australian dollars to 20,000 Australian dollars per DALY) but still well below 50,000 Australian dollars, which is considered the affordable threshold. Conclusions A range of cost-effective interventions for…
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“the costs for group therapy are less than half the costs for individual therapy [22].”
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Metadata
- Authors
- Vos, T., Corry, J., Haby, M. M., Carter, R., & Andrews, G.
- Affiliations
- The University of Queensland (AU)
- UNSW Sydney (AU)
- Department of Health and Human Services (AU)
- The University of Melbourne (AU)
- Corresponding author
- Vos, Theo
- Venue
- Australian & New Zealand Journal of Psychiatry
- Publisher
- SAGE Publications
- Published
- 2005-08
- Volume
- 39
- Issue
- 8
- Pages
- 683-692
- ISSN
- 0004-8674 (ISSN-L)
- 1440-1614
- OpenAlex
- W2135823835
- Cited by
- 114
- References
- 50
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 4 · 2023: 3 · 2022: 1 · 2021: 2 · 2020: 3 · 2019: 3 · 2018: 7 · 2017: 6 · 2016: 6 · 2015: 4 · 2014: 5 · 2013: 11 · 2012: 13
- FWCI
- 16.30
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Australian & New Zealand Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Keywords
- major depressive disorder, cost-effectiveness, cognitive behavioral therapy, antidepressants, maintenance therapy, selective serotonin reuptake inhibitors, tricyclic antidepressants, bibliotherapy, group cognitive behavioral therapy, disability-adjusted life years, health policy
- MeSH terms
- Antidepressive Agents, Australia, Cost-Benefit Analysis, Major Depressive Disorder, Humans, Mental Health Services, Cognitive Behavioral Therapy
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