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Cited by 116Forensic Toxicology and Drug AnalysisPharmacological Effects and AssaysDoping in Sports

The DOI matches its Crossref record; 138 of the 139 references it cites were found in a registry or an index.

ILLEGAL OR LEGITIMATE USE? PRECURSOR COMPOUNDS TO AMPHETAMINE AND METHAMPHETAMINE

MUSSHOFF, F.·2000·Drug Metabolism Reviews
DOI 10.1081/dmr-100100562
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Abstract

The interpretation of methamphetamine and amphetamine positive test results in biological samples is a challenge to clinical and forensic toxicology for several reasons. The effects of pH and dilution of urine samples and the knowledge about legitimate and illicit sources have to be taken into account. Besides a potentially legal prescription of amphetamines, many substances metabolize to methamphetamine or amphetamine in the body: amphetaminil, benzphetamine, clobenzorex, deprenyl, dimethylamphetamine, ethylamphetamine, famprofazone, fencamine, fenethylline, fenproporex, furfenorex, mefenorex, mesocarb, and prenylamine. Especially the knowledge of potential origins of methamphetamine and amphetamine turns out to be very important to prevent a misinterpretation of the surrounding circumstances and to prove illegal drug abuse. In this review, potential precursor compounds are described, including their medical use and major clinical effects and their metabolic profiles, as well as some clues which help to identify the sources.

Overview

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Crossref · 10.1081/dmr-100100562

Cites

138 of 138 references verified0 citation errors · 0 not checkable

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Citations

Cites

Research works printed but not linked: 28

  1. 1996, Physician's Desk Reference
  2. Cody J, 1993, Forensic Sci. Rev., 5, 109
  3. Cody J, 1994, Forensic Sci. Rev., 6, 81
  4. Hutchaleelaha A., 1994, Drug Metab. Dispos., 22, 406
  5. Meyer-Probst B., 1976, Psychiatr. Neurol. Med. Psychol., 28, 491
  6. Besserer K, 1972, Drug Res., 22, 1737
  7. Honecker H, 1975, Int. J. Clin. Pharmacol. Biopharm., 12, 121
  8. Beyer K., 1971, Dtsch. Apoth. Ztg., 111, 677
  9. Hoffmann H, 1971, Dtsch. Apoth. Ztg., 111, 680
  10. Honecker V H., 1975, Drug Res., 25, 442
  11. Glasson B., 1971, Drug Res., 21, 1985
  12. Knoll J, 1986, J. Neural Transmiss., 22, 75
  13. Szebeni G., 1995, Acta Physiol. Hung., 83, 135
  14. Heinonen E. H., 1989, Acta Neurol. Scand., 126, 93
  15. Delbeke F. T., 1986, Drug Res., 36, 1413
  16. Mrongovius R., 1984, Eur. J. Med. Chem. Chim. Therap., 19, 161
  17. Mallol J., 1974, Drug Res., 24, 1301
  18. Iffland R, 1982, Arch. Kriminol., 169, 81
  19. Goenechea S., 1984, Arch. Kriminol., 173, 97
  20. Rücker G., 1988, Drug Res., 38, 497
  21. Boissier J. R., 1968, Ann. Pharm. Fr., 26, 215
  22. Beyer G., 1980, Med. Welt., 31, 306
  23. Blum J. E, 1969, Drug Res., 19, 748
  24. Leary W. P., 1976, Curr. Therap. Res. Clin. Exp., 19, 180
  25. Manning A., 1985, Adv. Mycardiol., 6, 515
  26. Gietl Y., 1989, Drug Res., 39, 853
  27. Hornke I., 1970, Drug Res., 20, 791
  28. Jefferson J. W, 1992, J. Clin. Psychiatry, 53, 450

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Metadata

Authors
MUSSHOFF, F.
Affiliations
University of Bonn (DE)
Corresponding author
MUSSHOFF, F.
ORCID
MUSSHOFF, F.
Venue
Drug Metabolism Reviews
Publisher
Informa UK Limited
Published
2000-01
Volume
32
Issue
1
Pages
15-44
ISSN
  • 0360-2532 (ISSN-L)
  • 1097-9883
DOI
10.1081/dmr-100100562
OpenAlex
W2019322128
Cited by
116
References
139
Citations by year
2026: 2 · 2025: 4 · 2024: 3 · 2023: 2 · 2022: 6 · 2021: 6 · 2020: 6 · 2018: 4 · 2017: 1 · 2016: 5 · 2015: 2 · 2014: 7 · 2013: 3 · 2012: 11
FWCI
7.24
Type
journal article
Language
en
Open access
closed
Locations
  • Drug Metabolism Reviews (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Forensic Toxicology and Drug Analysis
  • Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Pharmacological Effects and Assays
  • Social Sciences › Sociology and Political Science › Doping in Sports
Keywords
amphetamine, methamphetamine, precursors, drug metabolites, urine drug testing, prescription drugs, drug metabolism, forensic toxicology, clinical toxicology, drug abuse
MeSH terms
Amphetamines, Animals, Benzphetamine, Furans, Hair, Humans, Methamphetamine, Pyrazoles, Selegiline, Sydnones, Theophylline, Pyrazolones

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