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TAILORING TISSUE ENGINEERING SCAFFOLDS USING ELECTROSTATIC PROCESSING TECHNIQUES: A STUDY OF POLY(GLYCOLIC ACID) ELECTROSPINNING
Abstract
Poly(glycolic acid) (PGA) has long been a popular polymer in the tissue engineering field. PGA possesses many favorable properties such as biocompatibility, bioabsorbability, and tensile strength. The traditional fiber formation techniques of melt extrusion and cold-drawing are generally limited to fibers of 10–12 μm in diameter. Electrostatic spinning, or electrospinning, is an attractive approach for the production of much smaller diameter fibers which are of interest as tissue engineering scaffolds. We demonstrate the ability to control the fiber diameter of PGA as a function of solution concentration and fiber orientation, as well as show a correlation between the fiber orientation, elastic modulu, and strain to failure of PGA in a uniaxial model.
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Citations
Cited by
Experimental investigation of the governing parameters in the electrospinning of polymer solutions
Theron, S. A., Zussman, E., & Yarin, A. L. (2004) · Polymer · doi:10.1016/j.polymer.2004.01.024 · Cited by 1,021
One‐Dimensional Composite Nanomaterials: Synthesis by Electrospinning and Their Applications
Lu, X., Wang, C., & Wei, Y. (2009) · Small · doi:10.1002/smll.200900445 · Cited by 874
Electrospinning for tissue engineering scaffolds
Lannutti, J., Reneker, D., Ma, T., Tomasko, D., & Farson, D. (2007) · Materials Science and Engineering: C · doi:10.1016/j.msec.2006.05.019 · Cited by 693
Electrospun fine-textured scaffolds for heart tissue constructs
Zong, X., Bien, H., Chung, C.-Y., Yin, L., Fang, D., Hsiao, B. S., Chu, B., & Entcheva, E. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.01.052 · Cited by 641
Nanofiber Assembly by Rotary Jet-Spinning
Badrossamay, M. R., McIlwee, H. A., Goss, J. A., & Parker, K. K. (2010) · Nano Letters · doi:10.1021/nl101355x · Cited by 518
Metadata
- Authors
- Boland, E., Wnek, G., Simpson, D., Pawlowski, K., & Bowlin, G.
- Venue
- Journal of Macromolecular Science, Part A
- Publisher
- Informa UK Limited
- Published
- 2001-11-30
- Volume
- 38
- Issue
- 12
- Pages
- 1231-1243
- ISSN
- 1060-1325 (ISSN-L)
- OpenAlex
- W2111296762
- Cited by
- 464
- References
- 0
- FWCI
- 9.72
- Type
- journal article
- Language
- en
- Open access
- closed
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- Boland, E., Wnek, G., Simpson, D., Pawlowski, K., & Bowlin, G. (2001). TAILORING TISSUE ENGINEERING SCAFFOLDS USING ELECTROSTATIC PROCESSING TECHNIQUES: A STUDY OF POLY(GLYCOLIC ACID) ELECTROSPINNING. Journal of Macromolecular Science, Part A. https://doi.org/10.1081/ma-100108380
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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