The DOI matches its Crossref record.
Endothelial cell membranes contain podocalyxin--the major sialoprotein of visceral glomerular epithelial cells.
Open accessAbstract
Podocalyxin is the major sialoprotein in the glycocalyx of glomerular podocytes. Here we report on its extraglomerular localization, using a monospecific antibody which was obtained by affinity purification of IgG on nitrocellulose transfers of glomerular podocalyxin. By indirect immunofluorescence, podocalyxin was found in the blood vessels of several organs (lung, heart, kidney, small intestine, brain, pancreas, aorta, the periportal blood vessels in liver, and the central arteries of follicles of the spleen, but not in the endothelia that line the sinusoids of the latter organs). By immunoelectron microscopy--using immunogold conjugates in diffusion ("pre-embedding") and surface ("postembedding") procedures--podocalyxin was localized on the luminal membrane domain of endothelial cells, in a patchy distribution. The presence of podocalyxin was confirmed in SDS extracts of lung tissue by immunoblotting. We conclude that (a) podocalyxin is a widespread component of endothelial plasma membranes, (b) it is restricted to the luminal membrane domain, and (c) it is distributed unevenly on the endothelial cell surface.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Hartleben, B., Gödel, M., Meyer-Schwesinger, C., Liu, S., Ulrich, T., Köbler, S., Wiech, T., Grahammer, F., Arnold, S. J., Lindenmeyer, M. T., et al. (2010) · Journal of Clinical Investigation · doi:10.1172/jci39492 · Cited by 721
Self-citationMolecular mimicry in pauci-immune focal necrotizing glomerulonephritis
Kain, R., Exner, M., Brandes, R., Ziebermayr, R., Cunningham, D., Alderson, C. A., Davidovits, A., Raab, I., Jahn, R., Ashour, O., et al. (2008) · Nature Medicine · doi:10.1038/nm.1874 · Cited by 455
Self-citationRegele, H., Böhmig, G. A., Habicht, A., Gollowitzer, D., Schillinger, M., Rockenschaub, S., Watschinger, B., Kerjaschki, D., & Exner, M. (2002) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000025780.03790.0f · Cited by 423
Self-citationUltrastructural Cytochemistry of Blood-Brain Barrier Endothelia
Vorbrodt, A. W. (1988) · Progress in Histochemistry and Cytochemistry · doi:10.1016/s0079-6336(88)80001-9 · Cited by 108
Hypoxia inducible factor-1α correlates with VEGF-C expression and lymphangiogenesis in breast cancer
Schoppmann, S. F., Fenzl, A., Schindl, M., Bachleitner-Hofmann, T., Nagy, K., Gnant, M., Horvat, R., Jakesz, R., & Birner, P. (2006) · Breast Cancer Research and Treatment · doi:10.1007/s10549-006-9190-3 · Cited by 106
Self-citation
Metadata
- Authors
- Horvat, R., Hovorka, A., Dekan, G., Poczewski, H., & Kerjaschki, D.
- Venue
- The Journal of cell biology
- Publisher
- Rockefeller University Press
- Published
- 1986-02-01
- Volume
- 102
- Issue
- 2
- Pages
- 484-491
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2105978645
- Cited by
- 211
- References
- 0
- FWCI
- 3.73
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Endothelial cell membranes contain podocalyxin--the major sialoprotein of visceral glomerular epithelial cells. https://app.cochat.ai/papers/10.1083/jcb.102.2.484
- The paper
- Horvat, R., Hovorka, A., Dekan, G., Poczewski, H., & Kerjaschki, D. (1986). Endothelial cell membranes contain podocalyxin--the major sialoprotein of visceral glomerular epithelial cells. The Journal of cell biology. https://doi.org/10.1083/jcb.102.2.484
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
