The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Mapping replicational sites in the eucaryotic cell nucleus.
Open accessAbstract
We have used fluorescent microscopy to map DNA replication sites in the interphase cell nucleus after incorporation of biotinylated dUTP into permeabilized PtK-1 kangaroo kidney or 3T3 mouse fibroblast cells. Discrete replication granules were found distributed throughout the nuclear interior and along the periphery. Three distinct patterns of replication sites in relationship to chromatin domains in the cell nucleus and the period of S phase were detected and termed type I (early to mid S), type II (mid to late S) and type III (late S). Similar patterns were seen with in vivo replicated DNA using antibodies to 5-bromodeoxyuridine. Extraction of the permeabilized cells with DNase I and 0.2 M ammonium sulfate revealed a striking maintenance of these replication granules and their distinct intranuclear arrangements with the remaining nuclear matrix structures despite the removal of greater than 90% of the total nuclear DNA. The in situ prepared nuclear matrix structures also incorporated biotinylated dUTP into replication granules that were indistinguishable from those detected within the intact nucleus.
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Cites
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Cited by
Visualization of focal sites of transcription within human nuclei.
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Heterogeneity of eukaryotic replicons, replicon clusters, and replication foci
Berezney, R., Dubey, D. D., & Huberman, J. A. (2000) · Chromosoma · doi:10.1007/s004120050399 · Cited by 370
Self-citationStructure and dynamics of human interphase chromosome territories in vivo
Zink, D., Cremer, T., Saffrich, R., Fischer, R., Trendelenburg, M. F., Ansorge, W., & Stelzer, E. H. K. (1998) · Human Genetics · doi:10.1007/s004390050686 · Cited by 347
A view of Interphase Chromosomes
Manuelidis, L. (1990) · Science · doi:10.1126/science.2274784 · Cited by 333
Aiolos Regulates B Cell Activation and Maturation to Effector State
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Metadata
- Authors
- Nakayasu, H., & Berezney, R.
- Venue
- The Journal of cell biology
- Publisher
- Rockefeller University Press
- Published
- 1989-01-01
- Volume
- 108
- Issue
- 1
- Pages
- 1-11
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W1971045116
- Cited by
- 520
- References
- 31
- FWCI
- 9.79
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
