The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway.
Open accessAbstract
The folate receptor, also known as the membrane folate-binding protein, is maximally expressed on the surface of folate-depleted tissue culture cells and mediates the high affinity accumulation of 5-methyltetrahydrofolic acid in the cytoplasm of these cells. Recent evidence suggests that this receptor recycles during folate internalization and that it is anchored in the membrane by a glycosyl-phosphatidylinositol linkage. Using quantitative immunocytochemistry, we now show that (a) this receptor is highly clustered on the cell surface; (b) these clusters are preferentially associated with uncoated membrane invaginations rather than clathrin-coated pits; and (c) the receptor is not present in endosomes or lysosomes. This receptor appears to physically move in and out of the cell using a novel uncoated pit pathway that does not merge with the clathrin-coated pit endocytic machinery.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Internalization and degradation of macrophage Fc receptors bound to polyvalent immune complexes.
Mellman, I., & Plutner, H. (1984) · The Journal of cell biology · doi:10.1083/jcb.98.4.1170 · Cited by 251
Cited by
Folic Acid: Nutritional Biochemistry, Molecular Biology, and Role in Disease Processes
Lucock, M. (2000) · Molecular Genetics and Metabolism · doi:10.1006/mgme.2000.3027 · Cited by 815
Membrane Compartmentation Is Required for Efficient T Cell Activation
Xavier, R., Brennan, T., Li, Q., McCormack, C., & Seed, B. (1998) · Immunity · doi:10.1016/s1074-7613(00)80577-4 · Cited by 690
Targeting folate receptor alpha for cancer treatment
Cheung, A., Bax, H. J., Josephs, D. H., Ilieva, K. M., Pellizzari, G., Opzoomer, J., Bloomfield, J., Fittall, M., Grigoriadis, A., Figini, M., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.9651 · Cited by 430
Cuitino, L., Matute, R., Retamal, C., Bu, G., Inestrosa, N. C., & Marzolo, M. (2005) · Traffic · doi:10.1111/j.1600-0854.2005.00320.x · Cited by 72
Molecular mechanism of substrate recognition by folate transporter SLC19A1
Dang, Y., Zhou, D., Du, X., Zhao, H., Lee, C.-H., Yang, J., Wang, Y., Qin, C., Guo, Z., & Zhang, Z. (2022) · Cell Discovery · doi:10.1038/s41421-022-00508-w · Cited by 33
Metadata
- Authors
- Rothberg, K. G., Ying, Y. S., Kolhouse, J. F., Kamen, B. A., & Anderson, R. G.
- Venue
- The Journal of cell biology
- Publisher
- Rockefeller University Press
- Published
- 1990-03-01
- Volume
- 110
- Issue
- 3
- Pages
- 637-649
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2063431146
- Cited by
- 441
- References
- 1
- FWCI
- 16.15
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
