The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
92-kD type IV collagenase mediates invasion of human cytotrophoblasts.
Open accessAbstract
The specialized interaction between embryonic and maternal tissues is unique to mammalian development. This interaction begins with invasion of the uterus by the first differentiated embryonic cells, the trophoblasts, and culminates in formation of the placenta. The transient tumor-like behavior of cytotrophoblasts, which peaks early in pregnancy, is developmentally regulated. Likewise, in culture only early-gestation human cytotrophoblasts invade a basement membrane-like substrate. These invasive cells synthesize both metalloproteinases and urokinase-type plasminogen activator. Metalloproteinase inhibitors and a function-perturbing antibody specific for the 92-kD type IV collagen-degrading metalloproteinase completely inhibited cytotrophoblast invasion, whereas inhibitors of the plasminogen activator system had only a partial (20-40%) inhibitory effect. We conclude that the 92-kD type IV collagenase is critical for cytotrophoblast invasion.
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Cites
Ignotz, R. A., & Massagué, J. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)35666-1 · Cited by 2,492
Regulation of Cell Adhesion Receptors by Transforming Growth Factor-β
Ignotz, R. A., Heino, J., & Massagué, J. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)31270-x · Cited by 269
Cited by
Genetic conflicts in human pregnancy
Haig, D. (1993) · The Quarterly Review of Biology · doi:10.1086/418300 · Cited by 1,253
“…deploy an arsenal of proteases to breach the decidual barricades (Puistola et al., 1989; U. M. Moll and Lane, 1990; Bischof et al., 1991; Librach et al., 1991; Zini et al., 1992) and decidual cells, in turn, secrete protease inhibitors to impede the advance (Graifenberg, 1910; Liedholm…”
BackgroundCaniggia, I., Mostachfi, H., Winter, J., Gassmann, M., Lye, S. J., Kuliszewski, M., & Post, M. (2000) · Journal of Clinical Investigation · doi:10.1172/jci8316 · Cited by 644
Trophoblast L-Selectin-Mediated Adhesion at the Maternal-Fetal Interface
Genbacev, O. D., Prakobphol, A., Foulk, R. A., Krtolica, A. R., Ilic, D., Singer, M. S., Yang, Z.-Q., Kiessling, L. L., Rosen, S. D., & Fisher, S. J. (2003) · Science · doi:10.1126/science.1079546 · Cited by 476
Self-citationBlavier, L., & Delaissé, J. M. (1995) · Journal of Cell Science · doi:10.1242/jcs.108.12.3649 · Cited by 221
Identification of the membrane-type matrix metalloproteinase MT1-MMP in osteoclasts
Sato, T., Ovejero, M. D. C., Hou, P., Heegaard, A.-M., Kumegawa, M., Tækker Foged, N., & Delaissé, J.-M. (1997) · Journal of Cell Science · doi:10.1242/jcs.110.5.589 · Cited by 214
Metadata
- Authors
- Librach, C. L., Werb, Z., Fitzgerald, M. L., Chiu, K., Corwin, N. M., Esteves, R. A., Grobelny, D., Galardy, R., Damsky, C. H., & Fisher, S. J.
- Venue
- The Journal of cell biology
- Publisher
- Rockefeller University Press
- Published
- 1991-04-15
- Volume
- 113
- Issue
- 2
- Pages
- 437-449
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2155925117
- Cited by
- 720
- References
- 2
- FWCI
- 20.17
- Type
- journal article
- Language
- en
- Open access
- green
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- Librach, C. L., Werb, Z., Fitzgerald, M. L., Chiu, K., Corwin, N. M., Esteves, R. A., Grobelny, D., Galardy, R., Damsky, C. H., & Fisher, S. J. (1991). 92-kD type IV collagenase mediates invasion of human cytotrophoblasts. The Journal of cell biology. https://doi.org/10.1083/jcb.113.2.437
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