The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope.
Open accessAbstract
Nuclear protein import can be separated into two distinct steps: binding to the nuclear pore complex followed by translocation to the nuclear interior. A previously identified nuclear location sequence (NLS) receptor and a 97-kD protein purified from bovine erythrocytes reconstitute the binding step in a permeabilized cell assay. Binding to the envelope is specific for a functional SV-40 large T antigen NLS and is not ATP or temperature dependent. Modification of p97 with N-ethylmaleimide (NEM) decreases binding to the pore, but interestingly, NEM treatment of the NLS receptor does not. Nuclear envelope binding is inhibited by wheat germ agglutinin suggesting a possible mechanism for the inhibition of transport by the lectin.
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Citations
Cites
Nuclear targeting sequences — a consensus?
Dingwall, C., & Laskey, R. A. (1991) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(91)90184-w · Cited by 1,876
Robbins, J., Dilwortht, S. M., Laskey, R. A., & Dingwall, C. (1991) · Cell · doi:10.1016/0092-8674(91)90245-t · Cited by 1,489
Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors.
Adam, S. A., Marr, R. S., & Gerace, L. (1990) · The Journal of cell biology · doi:10.1083/jcb.111.3.807 · Cited by 896
Self-citationThe GTP-binding protein Ran/TC4 is required for protein import into the nucleus
Moore, M. S., & Blobel, G. (1993) · Nature · doi:10.1038/365661a0 · Cited by 759
Identification and characterization of a nuclear pore complex protein
Davis, L. I., & Blobel, G. (1986) · Cell · doi:10.1016/0092-8674(86)90784-1 · Cited by 617
Garcia-Bustos, J., Heitman, J., & Hall, M. N. (1991) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(91)90013-m · Cited by 549
Melchior, F. (1993) · The Journal of Cell Biology · doi:10.1083/jcb.123.6.1649 · Cited by 544
Monoclonal antibodies identify a group of nuclear pore complex glycoproteins.
Snow, C. M., Senior, A., & Gerace, L. (1987) · The Journal of cell biology · doi:10.1083/jcb.104.5.1143 · Cited by 538
Richardson, W. D., Mills, A. D., Dilworth, S. M., Laskey, R. A., & Dingwall, C. (1988) · Cell · doi:10.1016/0092-8674(88)90403-5 · Cited by 530
Nuclear import can be separated into distinct steps in vitro: Nuclear pore binding and translocation
Newmeyer, D. D., & Forbes, D. J. (1988) · Cell · doi:10.1016/0092-8674(88)90402-3 · Cited by 525
Cited by
Nucleocytoplasmic transport: the soluble phase
Mattaj, I. W., & Englmeier, L. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.265 · Cited by 1,175
Purification of a Ran-interacting protein that is required for protein import into the nucleus.
Moore, M. S., & Blobel, G. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.21.10212 · Cited by 320
The role of the nuclear pore complex in adenovirus DNA entry
Greber, U. F., Suomalainen, M., Stidwill, R. P., Boucke, K., Ebersold, M. W., & Helenius, A. (1997) · The EMBO Journal · doi:10.1093/emboj/16.19.5998 · Cited by 299
Fagerlund, R., Melén, K., Kinnunen, L., & Julkunen, I. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m202943200 · Cited by 183
Regulation, mechanisms and proposed function of ferritin translocation to cell nuclei
Thompson, K. J., Fried, M. G., Ye, Z., Boyer, P., & Connor, J. R. (2002) · Journal of Cell Science · doi:10.1242/jcs.115.10.2165 · Cited by 110
Metadata
- Authors
- Adam, E. J., & Adam, S. A.
- Venue
- The Journal of cell biology
- Publisher
- Rockefeller University Press
- Published
- 1994-05-01
- Volume
- 125
- Issue
- 3
- Pages
- 547-555
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2146018121
- Cited by
- 304
- References
- 42
- FWCI
- 17.40
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
