Detection of a Novel Intraneuronal Pool of Insoluble Amyloid β Protein that Accumulates with Time in Culture

Cited by (287)

Items 101–200 of 287

1. Presenilins are not required for Aβ42 production in the early secretory pathway
   Clare Wilson, Robert W. Doms, Hui Zheng, Virginia M.‐Y. Lee · 2002 · Nature Neuroscience
2. Parkin promotes intracellular A 1-42 clearance
   Mark P. Burns, L. Zhang, George William Rebeck, Henry W. Querfurth, Charbel Moussa · 2009 · Human Molecular Genetics
3. Structure of amyloid oligomers and their mechanisms of toxicities: Targeting amyloid oligomers using novel therapeutic approaches
   Parveen Salahuddin, Munazza Tamkeen Fatima, Ali S. Abdelhameed, Saima Nusrat, Rizwan Hasan Khan · 2016 · European Journal of Medicinal Chemistry
4. Cerebral amyloid angiopathy: pathogenetic mechanisms and link to dense amyloid plaques
   Samir Kumar‐Singh · 2008 · Genes Brain & Behavior
5. Endoplasmic Reticulum Stress-induced Cysteine Protease Activation in Cortical Neurons
   Robert G. Siman, Dorothy G. Flood, Gopal Thinakaran, Robert W. Neumar · 2001 · Journal of Biological Chemistry
6. Aβ Internalization by Neurons and Glia
   Amany Mohamed, E Chaves · 2011 · International Journal of Alzheimer s Disease
7. Endothelin-converting Enzymes Degrade Intracellular β-Amyloid Produced within the Endosomal/Lysosomal Pathway and Autophagosomes*
   Javier Pacheco-Quinto, E. Eckman · 2013 · Journal of Biological Chemistry
8. Expression of β-Amyloid Precursor Protein-CD3γ Chimeras to Demonstrate the Selective Generation of Amyloid β1–40and Amyloid β1–42 Peptides within Secretory and Endocytic Compartments
   Salvador Soriano, Abraham S.C. Chyung, Xiaohua Chen, Gorazd Bernard Stokin, Virginia M.‐Y. Lee, Edward H. Koo · 1999 · Journal of Biological Chemistry
9. Separation of presenilin function in amyloid β-peptide generation and endoproteolysis of Notch
   Luka Kulic, Jochen Walter, Gerd Multhaup, David B. Teplow, Ralf Baumeister, Helmut Romig, Anja Capell, Harald Steiner, Christian Haass · 2000 · Proceedings of the National Academy of Sciences
10. Parkin Protects against Mitochondrial Toxins and β-Amyloid Accumulation in Skeletal Muscle Cells
    Kenneth M. Rosen, Vimal Veereshwarayya, Charbel Moussa, Qinghao Fu, Matthew S. Goldberg, Michael G. Schlossmacher, Jie Shen, Henry W. Querfurth · 2006 · Journal of Biological Chemistry
11. Cholesterol depletion reduces aggregation of amyloid-beta peptide in hippocampal neurons
    Anja Schneider, Walter Schulz‐Schaeffer, Tobias Hartmann, Jörg Bernhard Schulz, Mikael Simons · 2006 · Neurobiology of Disease
12. Early intraneuronal Aβ deposition in the hippocampus of APP transgenic mice
    Feng‐Shiun Shie, Renée C. LeBoeur, Lee‐Way Jin · 2003 · Neuroreport
13. Evidence of intraneuronal Aβ accumulation preceding tau pathology in the entorhinal cortex
    Lindsay A. Welikovitch, Sonia Do Carmo, Zsófia Maglóczky, Péter Szocsics, János Lőke, Tamás F. Freund, A. Claudio Cuello · 2018 · Acta Neuropathologica
14. Consistent immunohistochemical detection of intracellular β-amyloid42 in pyramidal neurons of Alzheimer's disease entorhinal cortex
    Michael R. D’Andrea, Robert G. Nagele, Hoau-Yan Wang, Daniel H. S. Lee · 2002 · Neuroscience Letters
15. Docosahexaenoic acid disrupts in vitro amyloid β1‐40 fibrillation and concomitantly inhibits amyloid levels in cerebral cortex of Alzheimer’s disease model rats
    Michio Hashimoto, Hossain Md Shahdat, Shinji Yamashita, Masanori Katakura, Yoko Tanabe, Hironori Fujiwara, Shuji Gamoh, Teruo Miyazawa, Hiroyuki Arai, Toshio Shimada et al. · 2008 · Journal of Neurochemistry
16. Secretion and Intracellular Generation of Truncated Aβ in β-Site Amyloid-β Precursor Protein-cleaving Enzyme Expressing Human Neurons
    Edward B. Lee, Daniel Skovronsky, Farhad Abtahian, Robert W. Doms, Virginia M.‐Y. Lee · 2003 · Journal of Biological Chemistry
17. Heme binding to Amyloid-β peptide: Mechanistic role in Alzheimer's disease
    Hani Atamna · 2006 · Journal of Alzheimer s Disease
18. Ultrastructural Localization of Intraneuronal Aβ-Peptide in Alzheimer Disease Brains
    Gómez-Ramos, Pilar, Asunción Morán, M. · 2007 · Journal of Alzheimer's Disease
19. Warning SINEs: Alu elements, evolution of the human brain, and the spectrum of neurological disease
    Peter A. Larsen, Kelsie E. Hunnicutt, Roxanne J. Larsen, Anne D. Yoder, Ann M. Saunders · 2018 · Chromosome Research
20. Alzheimer's disease, the nematode Caenorhabditis elegans, and ginkgo biloba leaf extract
    Yuan Luo · 2006 · Life Sciences
21. Tenuifolin, an extract derived from tenuigenin, inhibits amyloid‐β secretion in vitro
    J. Lv, H. Jia, Yong Jiang, Y. Ruan, Z. Liu, Wenhui Yue, Konrad T. Beyreuther, Peng‐Fei Tu, D. Zhang · 2009 · Acta Physiologica
22. A Distinct ER/IC γ-Secretase Competes with the Proteasome for Cleavage of APP
    Daniel Skovronsky, Donald S. Pijak, Robert W. Doms, Virginia M.‐Y. Lee · 1999 · Biochemistry
23. Intracellular A-Beta Amyloid, A Sign for Worse Things to Come?
    Valentina Echeverrı́a, A. Claudio Cuello · 2002 · Molecular Neurobiology
24. Overexpression of Neprilysin Reduces Alzheimer Amyloid-β42 (Aβ42)-induced Neuron Loss and Intraneuronal Aβ42 Deposits but Causes a Reduction in cAMP-responsive Element-binding Protein-mediated Transcription, Age-dependent Axon Pathology, and Premature Death in Drosophila
    Kanae Iijima‐Ando, Stephen Hearn, Linda Granger, Christopher Shenton, Anthony Gatt, Hsueh‐Cheng Chiang, Inessa Hakker, Yi Zhong, Koichi Iijima · 2008 · Journal of Biological Chemistry
25. Endoplasmic Reticulum‐Localized Amyloid β‐Peptide is Degraded in the Cytosol by Two Distinct Degradation Pathways
    Anton Schmitz, Andrea Schneider, Markus P. Kummer, Volker Herzog · 2003 · Traffic
26. Membrane Topology and Nicastrin-enhanced Endoproteolysis of APH-1, a Component of the γ-Secretase Complex
    Ryan R. Fortna, Adam Crystal, Vanessa A. Morais, Donald S. Pijak, Virginia M.‐Y. Lee, Robert W. Doms · 2004 · Journal of Biological Chemistry
27. The role of amyloids in Alzheimer's and Parkinson's diseases
    Parveen Salahuddin, Munazza Tamkeen Fatima, Vladimir Nikolaevich Uversky, Rizwan Hasan Khan, Zeyaul Islam, Mohammad Furkan · 2021 · International Journal of Biological Macromolecules
28. Differential Effects of Proteases Involved in Intracellular Degradation of Amyloid β-Protein between Detergent-Soluble and -Insoluble Pools in CHO-695 Cells
    Shinji Sudoh, Matthew P. Frosch, Bryan A. Wolf · 2002 · Biochemistry
29. β-Amyloid triggers ALS-associated TDP-43 pathology in AD models
    Alexander M. Herman, Preeti J. Khandelwal, Brenna B. Stanczyk, George William Rebeck, Charbel Moussa · 2011 · Brain Research
30. Isoprenoids and Alzheimer's disease: A complex relationship
    Sarah L. Cole, Robert J. Vassar · 2006 · Neurobiology of Disease
31. Mutations in APP have independent effects on Aβ and CTFγ generation
    Hecimovic, Silva, Wang, Jun, Dolios, Georgia, Martinez, Maribel, Wang, Rong, Goate, Alison M. · 2004 · Neurobiology of Disease
32. Nitric oxide in the cerebral cortex of amyloid-precursor protein (SW) Tg2576 transgenic mice
    José Rodrigo, P. Fernández‐Vizarra, Susana Castro‐Blanco, María Luisa Bentura, M. Nieto, Teresa Gómez‐Isla, Ricardo Martínez‐Murillo, Alfredo Martı́nez, Julia Serrano, Ana Patricia Fernández · 2004 · Neuroscience
33. The biological role of the Alzheimer amyloid precursor protein in epithelial cells
    Annika Schmitz, Ritva Tikkanen, Gregor Kirfel, Volker Herzog · 2001 · Histochemistry and Cell Biology
34. Aβ42 generation is toxic to endothelial cells and inhibits eNOS function through an Akt/GSK-3β signaling-dependent mechanism
    T Suhara · 2003 · Neurobiology of Aging
35. Amyloid and Alzheimer's Disease: Inside and Out
    Joshua H. K. Tam, Stephen Pasternak · 2012 · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
36. Recent advances in the understanding of the role of synaptic proteins in Alzheimer's Disease and other neurodegenerative disorders
    Eliezer Masliah · 2001 · Journal of Alzheimer s Disease
37. Transgenic Mice Over-Expressing the C-99 Fragment of βPP with an α-Secretase Site Mutation Develop a Myopathy Similar to Human Inclusion Body Myositis
    Lee-Way Jin, Mark G. Hearn, Charles E. Ogburn, Ngocthao Dang, David Nochlin, Warren Ladiges, George M. Martin · 1998 · American Journal Of Pathology
38. Visualization of co-localization in Aβ42-administered neuroblastoma cells reveals lysosome damage and autophagosome accumulation related to cell death
    Violetta Soura, Maris Stewart-Parker, Thomas L. Williams, J. Arjuna Ratnayaka, Joseph Atherton, Kirsti Gorringe, Jack P. Tuffin, Elisabeth Darwent, Roma N. Rambaran, William L. Klein et al. · 2011 · Biochemical Journal
39. Endocytic pathways mediating oligomeric Aβ42 neurotoxicity
    Chunjiang Yu, Evelyn Nwabuisi‐Heath, Kevin Laxton, Mary Jo LaDu · 2010 · Molecular Neurodegeneration
40. Intraneuronal amyloid β and reduced brain volume in a novel APP T714I mouse model for Alzheimer's disease
    Van Broeck, Bianca, Vanhoutte, Greet, Pirici, Daniel, Van Dam, Debby, Wils, Hans, Cuijt, Ivy, Vennekens, Krist’l, Zabielski, Monika, Michalik, Andrej, Theuns, Jessie et al. · 2008 · Neurobiology of Aging
41. Inhibition of Catalase Activity with 3-Amino-Triazole Enhances the Cytotoxicity of the Alzheimer’s Amyloid-β Peptide
    Nathaniel G.N. Milton · 2001 · NeuroToxicology
42. Regional hypometabolism in the 3xTg mouse model of Alzheimer's disease
    Aida Adlimoghaddam, Wanda M. Snow, Greg Stortz, Claudia Perez, Jelena Djordjevic, Andrew L. Goertzen, Ji Hyun Ko, Benedict C. Albensi · 2019 · Neurobiology of Disease
43. Biological roles of APP in the epidermis
    Volker Herzog, Gregor Kirfel, Christina Siemes, Anton Schmitz · 2004 · European Journal of Cell Biology
44. Amyloid-β precursor protein: Multiple fragments, numerous transport routes and mechanisms
    Virgil Mureşan, Zoia Ladescu Muresan · 2015 · Experimental Cell Research
45. Geranylgeranyl pyrophosphate stimulates γ‐secretase to increase the generation of Aβ and APP‐CTFγ
    Yan Zhou, Anitha Suram, Chitra Venugopal, Annamalai Prakasam, Suizhen Lin, Su Yuan, Baolin Li, Steven M. Paul, Kumar Sambamurti · 2007 · The FASEB Journal
46. Mechanisms of Glucose-Induced Secretion of Pancreatic-Derived Factor (PANDER or FAM3B) in Pancreatic β-Cells
    Yang, Jichun, Robert, Claudia E., Burkhardt, Brant R., Young, Robert A., Wu, Jianmei, Gao, Zhiyong, Wolf, Bryan A. · 2005 · Diabetes
47. Drosophila Models of Alzheimer's Amyloidosis: The Challenge of Dissecting the Complex Mechanisms of Toxicity of Amyloid-β 42
    Koichi Iijima, Kanae Iijima‐Ando · 2008 · Journal of Alzheimer s Disease
48. Cryptotanshinione Inhibits β-Amyloid Aggregation and Protects Damage from β-Amyloid in SH-SY5Y Cells
    Zhengrong Mei, Pengke Yan, Bing Situ, Yonggao Mou, Peiqing Liu · 2011 · Neurochemical Research
49. Phosphorylation of amyloid-β at the serine 26 residue by human cdc2 kinase
    Nathaniel G.N. Milton · 2001 · Neuroreport
50. Upregulation of APP endocytosis by neuronal aging drives amyloid-dependent synapse loss
    Tatiana Burrinha, Isak Martinsson, Ricardo A. Gomes, Ana Paula Terrasso, Gunnar K. Gouras, Cláudia Guimas Almeida · 2021 · Journal of Cell Science
51. The Effect of Aβ Conformation on the Metal Affinity and Aggregation Mechanism Studied by Circular Dichroism Spectroscopy
    Y.R. Chen, Hsien‐Bin Huang, C.L. Chyan, M S Shiao, T.H. Lin, Y.C. Chen · 2006 · The Journal of Biochemistry
52. Staging of Neurofibrillary Degeneration Caused by Human Tau Overexpression in a Unique Cellular Model of Human Tauopathy
    Garth F. Hall, Virginia M.‐Y. Lee, Gloria S. Lee, Jun Yao · 2001 · American Journal Of Pathology
53. Amyloid β-peptide levels in laser capture microdissected cornu ammonis 1 pyramidal neurons of Alzheimer's brain
    Aoki, Mikio, Volkmann, Inga, Tjernberg, Lars O., Winblad, Bengt, Bogdanovic, Nenad · 2008 · NeuroReport
54. Enhanced generation of intracellular Aβ42 amyloid peptide by mutation of presenilins PS1 and PS2
    Kazuya Takeda, Wataru Araki, Takeshi Tabira · 2004 · European Journal of Neuroscience
55. Neuronal death in Drosophila triggered by GAL4 accumulation
    Carolina Rezával, Santiago Werbajh, M. Fernanda Ceriani · 2007 · European Journal of Neuroscience
56. Subcellular Compartment and Molecular Subdomain of β-Amyloid Precursor Protein Relevant to the Aβ42-promoting Effects of Alzheimer Mutant Presenilin 2
    Hiroshi Iwata, Taisuke Tomita, Kei Maruyama, Takeshi Iwatsubo · 2001 · Journal of Biological Chemistry
57. Aβ(31–35) peptide induce apoptosis in PC 12 cells: Contrast with Aβ(25–35) peptide and examination of underlying mechanisms
    Francesco Misiti, Beatrice Sampaolese, Michela Pezzotti, Stefano Marini, Massimo Coletta, L CECCARELLI, Bruno Giardina, Maria Elisabetta Clementi · 2005 · Neurochemistry International
58. Critical analysis of Alzheimer rsquo s amyloid-beta nbsp toxicity to mitochondria
    Yury G. Kaminsky · 2015 · Frontiers in bioscience
59. Structural features of the KPI domain control APP dimerization, trafficking, and processing
    Naouel Ben Khalifa, Donatienne Tyteca, Claudia Marinangeli, Matthieu Depuydt, Jean‐François Collet, Pierre J. Courtoy, Jean‐Christophe Renauld, Stefan N. Constantinescu, Jean‐Noël Octave, Pascal Kienlen‐Campard · 2011 · The FASEB Journal
60. Closing in on the Amyloid Cascade
    Robert W. Doms, Jason T. Huse · 2000 · Molecular Neurobiology
61. HIG1, a novel regulator of mitochondrial γ‐secretase, maintains normal mitochondrial function
    Hiroki Hayashi, Hironori Nakagami, M Takeichi, Munehisa Shimamura, Nobutaka Koibuchi, Eiji Oiki, Naoyuki Sato, Hiroshi Koriyama, Masaki Mori, Rodriguez Gerardo Araujo et al. · 2012 · The FASEB Journal
62. Association of Neuropathological Markers in the Parietal Cortex With Antemortem Cognitive Function in Persons With Mild Cognitive Impairment and Alzheimer Disease
    Cyntia Tremblay, Arnaud François, Charlotte Delay, Laure Freland, Milène Vandal, David Alan Bennett, Frédéric Calon · 2017 · Journal of Neuropathology & Experimental Neurology
63. Chronic exposure to U18666A is associated with oxidative stress in cultured murine cortical neurons
    Chor Hui Vivien Koh, Matthew Whiteman, Q.-X. Li, Barry B. Halliwell, Andrew M. Jenner, Boon‐Seng Wong, Katrina M. Laughton, Markus Rene Wenk, Colin Louis Masters, Philip M. Beart et al. · 2006 · Journal of Neurochemistry
64. Generating Differentially Targeted Amyloid-β Specific Intrabodies as a Passive Vaccination Strategy for Alzheimer's Disease
    Kelly L. Sudol, Michael A. Mastrangelo, Wade C. Narrow, Maria E. Frazer, Yona Levites, Todd Eliot Golde, Howard J. Federoff, William J. Bowers · 2009 · Molecular Therapy
65. Human bleomycin hydrolase regulates the secretion of amyloid precursor protein
    Iliya M. Lefterov, Radosveta P. Koldamova, John Stephen Lazo · 2000 · The FASEB Journal
66. Mitogen-activated protein kinase signaling pathways are involved in regulating α7 nicotinic acetylcholine receptor-mediated amyloid-β uptake in SH-SY5Y cells
    Weina Yang, Kai Ma, X.L. Chen, Lili Shi, Guojun Bu, X.D. Hu, H. Han, Yundie Liu, Yi‐Hua Qian · 2014 · Neuroscience
67. BACE1 and BACE2 in pathologic and normal human muscle
    Gaetano Nicola Alfio Vattemi, W. King Engel, Janis McFerrin, Lucia Pastorino, Joseph D. Buxbaum, Valerie Askanas · 2003 · Experimental Neurology
68. Examination of potential mechanisms of amyloid-induced defects in neuronal transport
    Sameer B. Shah, Rhiannon L. Nolan, Emily Davis, Gorazd Bernard Stokin, Ingrid R. Niesman, Isabel Canto, Charles G. Glabe, Lawrence S.B. Goldstein · 2009 · Neurobiology of Disease
69. Amyloid-β-Induced Cytotoxicity of PC-12 Cell Was Attenuated by Shengmai-san Through Redox Regulation and Outgrowth Induction
    Hiroshi Nishida, Megumi Kushida, Yuki Nakajima, Yoshihiro Ogawa, Naoto Tatewaki, Shinji Sato, Tetsuya Konishi · 2007 · Journal of Pharmacological Sciences
70. In silico and in vitro characterization of anti-amyloidogenic activity of vitamin K3 analogues for Alzheimer's disease
    Pham Dinh Quoc Huy, Yao-Chung Yu, Sơn Tùng Ngô, Tran Van Thao, Chinpiao Chen, Mai Suan Li, Yi-Cheng Chen · 2013 · Biochimica et Biophysica Acta (BBA) - General Subjects
71. Localization of β-Secretase Memapsin 2 in the Brain of Alzheimer's Patients and Normal Aged Controls
    Anyang Sun, Gerald Koelsch, Jordan Tang, Guoying Bing · 2002 · Experimental Neurology
72. γ-Secretase Cleavage Site Specificity Differs for Intracellular and Secretory Amyloid β
    Heike S. Grimm, Dirk Beher, Stefan F. Lichtenthaler, Mark S. Shearman, Konrad T. Beyreuther, Tobias Hartmann · 2003 · Journal of Biological Chemistry
73. Wild type TDP-43 induces neuro-inflammation and alters APP metabolism in lentiviral gene transfer models
    Alexander M. Herman, Preeti J. Khandelwal, George William Rebeck, Charbel Moussa · 2012 · Experimental Neurology
74. Mutant Presenilin 1 Increases the Levels of Alzheimer Amyloid β‐Peptide Aβ42 in Late Compartments of the Constitutive Secretory Pathway
    Suzana S. Petanceska, Mary Seeger, Frédéric Checler, Sam Gandy · 2000 · Journal of Neurochemistry
75. Cryptotanshinione upregulates α-secretase by activation PI3K pathway in cortical neurons
    Zhengrong Mei, Bing Situ, Xiangping Tan, Shiming Zheng, Fangyan Zhang, Pengke Yan, Peiqing Liu · 2010 · Brain Research
76. Neuritic Deposits of Amyloid-β Peptide in a Subpopulation of Central Nervous System-Derived Neuronal Cells
    Zoia Ladescu Muresan, Virgil Mureşan · 2006 · Molecular and Cellular Biology
77. Molecular Pathology of Alzheimer’s Disease and Related Disorders
    Stephen D. Ginsberg, Marie Luise Schmidt, Peter B. Crino, James H. Eberwine, Virginia M.‐Y. Lee, John Q. Trojanowski · 1999 · Cerebral cortex
78. Distinct presenilin‐dependent and presenilin‐independent γ‐secretases are responsible for total cellular Aβ production
    Clare Wilson, Robert W. Doms, Virginia M.‐Y. Lee · 2003 · Journal of Neuroscience Research
79. Inhibiting Amyloid Precursor Protein C-terminal Cleavage Promotes an Interaction with Presenilin 1
    Giuseppe Verdile, Ralph Nigel Martins, Monika Duthie, Erin Holmes, Peter St George‐Hyslop, Paul E. Fraser · 2000 · Journal of Biological Chemistry
80. Research progress of natural products and their derivatives against Alzheimer’s disease
    Jinying Liu, Hongyan Guo, Zhe‐Shan Quan, Qing‐Kun Shen, Hong Cui, Xiaoting Li · 2023 · Journal of Enzyme Inhibition and Medicinal Chemistry
81. Biochemical Isolation of Insoluble Tau in Transgenic Mouse Models of Tauopathies
    Carl Julien, Alexis Bretteville, Emmanuel Planel · 2012 · Methods in molecular biology
82. Does Alzheimer disease tilt the scales of amyloid degradation versus accumulation?
    Charles G. Glabe · 2000 · Nature Medicine
83. A Curcumin Analog Reduces Levels of the Alzheimer’s Disease-Associated Amyloid-β Protein by Modulating AβPP Processing and Autophagy
    Yu Wan, Yingxia Liang, Feng Liang, Nolan Shen, Kenneth Shinozuka, Jin‐Tai Yu, Chongzhao Ran, Qimin Quan, Rudolph E. Tanzi, Can Martin Zhang · 2019 · Journal of Alzheimer s Disease
84. Cholesterol Secoaldehyde, An Ozonation Product of Cholesterol, Induces Amyloid Aggregation and Apoptosis in Murine GT1-7 Hypothalamic Neurons
    K. Sathishkumar, Xiaochun Xi, Roy Joseph Martin, Rao M. Uppu · 2007 · Journal of Alzheimer s Disease
85. Intracellular Aβ is increased by okadaic acid exposure in transfected neuronal and non-neuronal cell lines
    Xiaoyan Sun, Gregory M. Cole, Teresa Chu, Weiming Xia, Douglas Galasko, Haruyasu Yamaguchi, Kentaro Tanemura, Sally Ann Frautschy, Akihiko Takashima · 2002 · Neurobiology of Aging
86. ELISA analysis of β‐secretase cleavage of the Swedish amyloid precursor protein in the secretory and endocytic pathways
    Michelle Leigh Steinhilb, Raymond Scott Turner, James R. Gaut · 2002 · Journal of Neurochemistry
87. Proteolytic generation and aggregation of peptides from transmembrane regions: lung surfactant protein C and amyloid ?-peptide
    Jan Johansson, Timothy E. Weaver, Lars O. Tjernberg · 2004 · Cellular and Molecular Life Sciences
88. Cellular and molecular basis of beta-amyloid precursor protein metabolism
    Huaxi Xu · 1998 · Frontiers in bioscience
89. Identification of amyloid-β binding sites using an antisense peptide approach
    Nathaniel G.N. Milton, Neema P. Mayor, John Rawlinson · 2001 · Neuroreport
90. A presenilin‐independent aspartyl protease prefers the γ‐42 site cleavage
    Ming‐Tain Lai, Ming‐Chih Crouthamel, Jillian M. DiMuzio, Beth Pietrak, Dorit B. Donoviel, Alan Bernstein, Stephen J. Gardell, Yue‐Ming Li, Daria J. Hazuda · 2005 · Journal of Neurochemistry
91. Proposed mechanisms of tau: relationships to traumatic brain injury, Alzheimer’s disease, and epilepsy
    Samantha P. Martin, Beth A. Leeman-Markowski · 2024 · Frontiers in Neurology
92. The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity
    Julia Ring, Jelena Tadić, Selena Ristic, Michael Poglitsch, Martina Bergmann, Nemanja Radic, Dirk Mossmann, YongTian Liang, Marta Maglione, Andrea Jerkovic et al. · 2022 · EMBO Molecular Medicine
93. Parkin prevents cortical atrophy and Aβ-induced alterations of brain metabolism: 13C NMR and magnetic resonance imaging studies in AD models
    Norah Khaled Algarzae, Michaeline L. Hebron, Matthew Miessau, Charbel Moussa · 2012 · Neuroscience
94. Observation of multi-step conformation switching in β-amyloid peptide aggregation by fluorescence resonance energy transfer
    Jiho Kim, Minyung Lee · 2004 · Biochemical and Biophysical Research Communications
95. β-Secretase revealed: starting gate for race to novel therapies for Alzheimer’s disease
    Daniel Skovronsky, Virginia M.‐Y. Lee · 2000 · Trends in Pharmacological Sciences
96. Constitutively Active Akt Inhibits Trafficking of Amyloid Precursor Protein and Amyloid Precursor Protein Metabolites through Feedback Inhibition of Phosphoinositide 3-Kinase
    Diana W. Shineman, Aleksandra Sarah Dain, Minkyu L. Kim, Virginia M.‐Y. Lee · 2009 · Biochemistry
97. The relationship between parkin and protein aggregation in neurodegenerative diseases
    Preeti J. Khandelwal · 2010 · Frontiers in Psychiatry
98. Neuronal dysfunction in Down syndrome: Contribution of neuronal models in cell culture
    Katherine Saud, Christian Arriagada, Ana M. Cárdenas, Takeshi Shimahara, David D. Allen, Raúl Caviedes, Pablo A. Caviedes · 2006 · Journal of Physiology-Paris
99. Amyloid precursor protein α‐ and β‐cleaved ectodomains exert opposing control of cholesterol homeostasis via SREBP2
    Wei Wang, Aino Mutka, Uršula Prosenc Zmrzljak, Damjana Rozman, Heikki Tanila, Helena Gylling, Anne Marja Remes, Henri J. Huttunen, Elina Ikonen · 2013 · The FASEB Journal
100. The Amyloid Cascade Hypothesis 2.0 for Alzheimer’s Disease and Aging-Associated Cognitive Decline: From Molecular Basis to Effective Therapy
     Vladimir Volloch, Sophia Rits‐Volloch · 2023 · International Journal of Molecular Sciences