The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Pds5p Is an Essential Chromosomal Protein Required for Both Sister Chromatid Cohesion and Condensation in Saccharomyces cerevisiae
Open accessAbstract
The PDS5 gene (precocious dissociation of sisters) was identified in a genetic screen designed to identify genes important for chromosome structure. PDS5 is an essential gene and homologues are found from yeast to humans. Pds5p function is important for viability from S phase through mitosis and localizes to chromosomes during this cell cycle window, which encompasses the times when sister chromatid cohesion exists. Pds5p is required to maintain cohesion at centromere proximal and distal sequences. These properties are identical to those of the four cohesion complex members Mcd1p/Scc1p, Smc1p, Smc3p, and Scc3p/Irr1p (Guacci, V., D. Koshland, and A. Strunnikov. 1997. Cell. 91:47–57; Michaelis, C., R. Ciosk, and K. Nasmyth. 1997. Cell. 91:35–45; Toth, A., R. Ciosk, F. Uhlmann, M. Galova, A. Schleiffer, and K. Nasmyth. 1999. Genes Dev. 13:307–319). Pds5p binds to centromeric and arm sequences bound by Mcd1p. Furthermore, Pds5p localization to chromosomes is dependent on Mcd1p. Thus, Pds5p, like the cohesin complex members, is a component of the molecular glue that mediates sister chromatid cohesion. However, Mcd1p localization to chromosomes is independent of Pds5p, which may reflect differences in their roles in cohesion. Finally, Pds5p is required for condensation as well as cohesion, which confirms the link between these processes revealed through analysis of Mcd1p (Guacci, V., D. Koshland, and A. Strunnikov. 1997. Cell. 91:47–57). Therefore, the link between cohesion and condensation is a general property of yeast chromosomes.
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Cites
The Cell in Development and Heredity
Cleave, H. J. V., & Wilson, E. B. (1925) · Transactions of the American Microscopical Society · doi:10.2307/3221988 · Cited by 1,680
Cohesins: Chromosomal Proteins that Prevent Premature Separation of Sister Chromatids
Michaelis, C., Ciosk, R., & Nasmyth, K. (1997) · Cell · doi:10.1016/s0092-8674(01)80007-6 · Cited by 1,471
The molecular biology of the yeast saccharomyces: Life cycle and inheritance
Sherman, F. (1982) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(82)90271-7 · Cited by 1,323
Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1
Uhlmann, F., Lottspeich, F., & Nasmyth, K. (1999) · Nature · doi:10.1038/21831 · Cited by 943
Guacci, V., Koshland, D., & Strunnikov, A. (1997) · Cell · doi:10.1016/s0092-8674(01)80008-8 · Cited by 828
Self-citationCohesin’s binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins
Ciosk, R., Shirayama, M., Shevchenko, A., Tanaka, T., Toth, A., Shevchenko, A., & Nasmyth, K. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)80420-7 · Cited by 755
Identification of Xenopus SMC protein complexes required for sister chromatid cohesion
Losada, A., Hirano, M., & Hirano, T. (1998) · Genes & Development · doi:10.1101/gad.12.13.1986 · Cited by 601
Toth, A., Ciosk, R., Uhlmann, F., Galova, M., Schleiffer, A., & Nasmyth, K. (1999) · Genes & Development · doi:10.1101/gad.13.3.320 · Cited by 598
Straight, A. F., Belmont, A. S., Robinett, C. C., & Murray, A. W. (1996) · Current Biology · doi:10.1016/s0960-9822(02)70783-5 · Cited by 585
Hirano, T., Kobayashi, R., & Hirano, M. (1997) · Cell · doi:10.1016/s0092-8674(00)80233-0 · Cited by 540
Cited by
Nasmyth, K. (2001) · Annual Review of Genetics · doi:10.1146/annurev.genet.35.102401.091334 · Cited by 805
Wapl controls the dynamic association of cohesin with chromatin
Kueng, S., Hegemann, B., Peters, B. H., Lipp, J. J., Schleiffer, A., Mechtler, K., & Peters, J.-M. (2006) · Cell · doi:10.1016/j.cell.2006.09.040 · Cited by 624
Wahba, L., Amon, J. D., Koshland, D., & Vuica-Ross, M. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.10.017 · Cited by 401
Self-citationCohesin-mediated interactions organize chromosomal domain architecture
Sofueva, S., Yaffe, E., Chan, W., Georgopoulou, D., Vietri Rudan, M., Mira‐Bontenbal, H., Pollard, S. M., Schroth, G. P., Tanay, A., & Hadjur, S. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.237 · Cited by 394
Absence of Mouse REC8 Cohesin Promotes Synapsis of Sister Chromatids in Meiosis
Xu, H., Beasley, M. D., Warren, W. D., van der Horst, G. T. J., & McKay, M. J. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.03.018 · Cited by 351
Metadata
- Authors
- Hartman, T., Stead, K., Koshland, D., & Guacci, V.
- Venue
- The Journal of Cell Biology
- Publisher
- Rockefeller University Press
- Published
- 2000-10-30
- Volume
- 151
- Issue
- 3
- Pages
- 613-626
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W1969497434
- Cited by
- 273
- References
- 53
- FWCI
- 5.66
- Type
- journal article
- Language
- en
- Open access
- green
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- Hartman, T., Stead, K., Koshland, D., & Guacci, V. (2000). Pds5p Is an Essential Chromosomal Protein Required for Both Sister Chromatid Cohesion and Condensation in Saccharomyces cerevisiae. The Journal of Cell Biology. https://doi.org/10.1083/jcb.151.3.613
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