The DOI matches its Crossref record; 94 of the 94 references it cites were found in a registry or an index.
Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited
Open accessAbstract
Tissue invasion during metastasis requires cancer cells to negotiate a stromal environment dominated by cross-linked networks of type I collagen. Although cancer cells are known to use proteinases to sever collagen networks and thus ease their passage through these barriers, migration across extracellular matrices has also been reported to occur by protease-independent mechanisms, whereby cells squeeze through collagen-lined pores by adopting an ameboid phenotype. We investigate these alternate models of motility here and demonstrate that cancer cells have an absolute requirement for the membrane-anchored metalloproteinase MT1-MMP for invasion, and that protease-independent mechanisms of cell migration are only plausible when the collagen network is devoid of the covalent cross-links that characterize normal tissues.
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Cites
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Rapid leukocyte migration by integrin-independent flowing and squeezing
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Cited by
Hallmarks of Cancer: The Next Generation
Hanahan, D., & Weinberg, R. A. (2011) · Cell · doi:10.1016/j.cell.2011.02.013 · Cited by 66,590
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
Kessenbrock, K., Plaks, V., & Werb, Z. (2010) · Cell · doi:10.1016/j.cell.2010.03.015 · Cited by 5,151
Effects of extracellular matrix viscoelasticity on cellular behaviour
Chaudhuri, O., Cooper-White, J., Janmey, P. A., Mooney, D. J., & Shenoy, V. B. (2020) · Nature · doi:10.1038/s41586-020-2612-2 · Cited by 2,224
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Self-citationCollagen-Based Biomaterials for Tissue Engineering Applications
Parenteau-Bareil, R., Gauvin, R., & Berthod, F. (2010) · Materials · doi:10.3390/ma3031863 · Cited by 1,256
Metadata
- Authors
- Sabeh, F., Shimizu-Hirota, R., & Weiss, S. J.
- Venue
- Journal of Cell Biology
- Publisher
- Rockefeller University Press
- Published
- 2009-03-30
- Volume
- 185
- Issue
- 1
- Pages
- 11-19
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2076782790
- Cited by
- 658
- References
- 94
- FWCI
- 21.56
- Type
- journal article
- Language
- en
- Open access
- green
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- Sabeh, F., Shimizu-Hirota, R., & Weiss, S. J. (2009). Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited. Journal of Cell Biology. https://doi.org/10.1083/jcb.200807195
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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