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Cited by 469

The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

The concept of lipid domains in membranes.

Open access
Karnovsky, M J, Kleinfeld, A M, Hoover, R L, Klausner, R D·1982·The Journal of cell biology

Abstract

In the past two decades or so there has been considerable advance in our knowledge of membrane structure. The fluid mosaic model of Singer and Nicolson (1) has had great heuristic value in thinking about membrane topology. In this model both proteins and lipids are free to diffuse in the bilayer, implying a random organization of protein and lipid. However, experimental evidence in diverse types of membranes and for several protein entities indicates that the lateral motion of most proteins is not determined primarily by free diffusion through a two-dimensional viscous fluid, but is constrained, probably by mechanisms such as interactions with cytoskeletal components. We will here present our evidence that lipids may also have nonhomogeneity in their lateral distribution, i.e., the lipid may be organized in domains, and that such organizational

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Metadata

Authors
Karnovsky, M. J., Kleinfeld, A. M., Hoover, R. L., & Klausner, R. D.
Venue
The Journal of cell biology
Published
1982-07-01
Volume
94
Issue
1
Pages
1-6
ISSN
  • 0021-9525 (ISSN-L)
  • 1540-8140
OpenAlex
W2155268568
Cited by
469
References
13
FWCI
11.78
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The concept of lipid domains in membranes. https://app.cochat.ai/papers/10.1083/jcb.94.1.1
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Karnovsky, M. J., Kleinfeld, A. M., Hoover, R. L., & Klausner, R. D. (1982). The concept of lipid domains in membranes. The Journal of cell biology. https://doi.org/10.1083/jcb.94.1.1

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.