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HUMAN IMMUNITY TO THE MENINGOCOCCUS

Open access
Gotschlich, Emil C., Goldschneider, Irving, Artenstein, Malcolm S.·1969·The Journal of Experimental Medicine

Abstract

Purified meningococcal polysaccharides were administered to army recruits. No adverse reactions were observed in 145 men who received group C polysaccharide, and in 53 men who were injected with group A polysaccharide. Hemagglutinating and bactericidal activity developed in the sera of all individuals with the exception of two recruits injected with A polysaccharide. During the 6 wk period of observation, the proportion of unvaccinated recruits who acquired group C meningococci in the three companies studied was 38, 42, and 69 per cent. A significantly lower proportion of the individuals vaccinated with group C polysaccharide acquired group C meningococci; 4.6, 24, and 31 per cent respectively.

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Metadata

Authors
Gotschlich, E. C., Goldschneider, I., & Artenstein, M. S.
Venue
The Journal of Experimental Medicine
Published
1969-06-01
Volume
129
Issue
6
Pages
1385-1395
ISSN
  • 0022-1007 (ISSN-L)
  • 1540-9538
OpenAlex
W2060643819
Cited by
199
References
0
FWCI
14.42
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: HUMAN IMMUNITY TO THE MENINGOCOCCUS. https://app.cochat.ai/papers/10.1084/jem.129.6.1385
The paper
Gotschlich, E. C., Goldschneider, I., & Artenstein, M. S. (1969). HUMAN IMMUNITY TO THE MENINGOCOCCUS. The Journal of Experimental Medicine. https://doi.org/10.1084/jem.129.6.1385

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.