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Cited by 344

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

Clinical Efficacy of Meningococcus Group A Capsular Polysaccharide Vaccine in Children Three Months to Five Years of Age

Peltola, Heikki, Mäkelä, P. Helena, Käyhty, Helena, Jousimies, Hannele, Herva, Elja, Hällström, Kalevi, Sivonen, Aulikki, Renkonen, Olli-Veikko, Pettay, Ossi, Karanko, Viena, Ahvonen, Paavo, Sarna, Seppo·1977·New England Journal of Medicine
DOI 10.1056/nejm197709292971302
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Abstract

We performed field trials in the course of an epidemic in Finland to learn whether Group A memingococcal capsular polysaccharide vaccine protects infants and young children from meningitis. The first trial involved 130,178 children between the ages of three months and five years; 49,295 children received the vaccine, 48,977 received a control Haemophilus influenzae Type b polysaccharide vaccine, and 31.906 remained unvaccinated. No cases of meningitis or sepsis caused by Group A meningococci were seen in the first year of observation among the children vaccinated with meningococcal vaccine whereas six occurred among those vaccinated with the H. influenzae vaccine and 13 among those not vaccinated. In the second trial 21,007 children of the same ages received the meningococcal vaccine. No cases caused by Group A occurred among those vaccinated, although five to seven would have been expected within the year. Meningococcal Group A vaccine appears efficacious in young infants and children.

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Crossref · 10.1056/nejm197709292971302

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Metadata

Authors
Peltola, H., Mäkelä, P. H., Käyhty, H., Jousimies, H., Herva, E., Hällström, K., Sivonen, A., Renkonen, O.-V., Pettay, O., Karanko, V., Ahvonen, P., & Sarna, S.
Venue
New England Journal of Medicine
Publisher
Massachusetts Medical Society
Published
1977-09-29
Volume
297
Issue
13
Pages
686-691
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
DOI
10.1056/nejm197709292971302
OpenAlex
W2092326939
Cited by
344
References
8
FWCI
12.05
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Clinical Efficacy of Meningococcus Group A Capsular Polysaccharide Vaccine in Children Three Months to Five Years of Age. https://app.cochat.ai/papers/10.1056/nejm197709292971302
The paper
Peltola, H., Mäkelä, P. H., Käyhty, H., Jousimies, H., Herva, E., Hällström, K., Sivonen, A., Renkonen, O.-V., Pettay, O., Karanko, V., Ahvonen, P., & Sarna, S. (1977). Clinical Efficacy of Meningococcus Group A Capsular Polysaccharide Vaccine in Children Three Months to Five Years of Age. New England Journal of Medicine. https://doi.org/10.1056/nejm197709292971302

Data sources

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.