The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
C3 PROACTIVATOR CONVERTASE AND ITS MODE OF ACTION
Open accessAbstract
The activity in human serum which is responsible for conversion of C3 proactivator (C3PA) to C3 activator was shown to reside in a 3S α-globulin. The factor, called C3PA convertase (C3PAse), was obtained in partially purified form. For conversion of C3PA, C3PAse required participation of metal ions and of a C3 fragment, which in physicochemical and antigenic properties resembled C3b. Isolated, native C3 failed to substitute for the fragment, but did restore the impaired C3 activator system in hydrazine-treated serum. Unlike native C3, the C3 fragment initiated conversion of C3PA in whole serum. A hypothetical concept which envisions the C3 fragment as effector of C3PAse has been proposed.
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Cites
Nilsson, U. R., & Müller-Eberhard, H. J. (1965) · The Journal of Experimental Medicine · doi:10.1084/jem.122.2.277 · Cited by 412
Self-citationAlper, C. A., Abramson, N. R., Johnston, R. B., Jandl, J. H., & Rosen, F. S. (1970) · Journal of Clinical Investigation · doi:10.1172/jci106417 · Cited by 142
Cited by
Properdin: binding to C3b and stabilization of the C3b-dependent C3 convertase.
Fearon, D. T., & Austen, K. F. (1975) · The Journal of experimental medicine · doi:10.1084/jem.142.4.856 · Cited by 481
Complement control protein factor H: The good, the bad, and the inadequate
Ferreira, V. P., Pangburn, M. K., & Cortés, C. (2010) · Molecular Immunology · doi:10.1016/j.molimm.2010.05.007 · Cited by 420
Molecular Biology and Chemistry of the Alternative Pathway of Complement
Müller-Eberhard, H. J., & Schreiber, R. D. (1980) · Advances in Immunology · doi:10.1016/s0065-2776(08)60042-5 · Cited by 408
Pangburn, M. K., Schreiber, R. D., & Müller-Eberhard, H. J. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.17.5430 · Cited by 317
Pangburn, M. K., & Müller‐Eberhard, H. J. (1983) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1983.tb18116.x · Cited by 121
Metadata
- Authors
- Müller-Eberhard, H. J., & Götze, O.
- Venue
- The Journal of Experimental Medicine
- Publisher
- Rockefeller University Press
- Published
- 1972-04-01
- Volume
- 135
- Issue
- 4
- Pages
- 1003-1008
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W1978058154
- Cited by
- 324
- References
- 2
- FWCI
- 14.93
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Müller-Eberhard, H. J., & Götze, O. (1972). C3 PROACTIVATOR CONVERTASE AND ITS MODE OF ACTION. The Journal of Experimental Medicine. https://doi.org/10.1084/jem.135.4.1003
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
