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INTERACTION OF AGGREGATED γ-GLOBULIN WITH B LYMPHOCYTES
Open accessAbstract
Specific binding of aggregated γ-globulin to a subpopulation of lymphocytes was demonstrated. This subpopulation was identified as the Ig-staining or B lymphocytes. The binding was irreversible and independent of complement, pH, temperature, protein content of the medium, and divalent cations. Aggregates of large size were needed for optimal visualization. Evidence was obtained that the site on the lymphocyte membrane responsible for binding aggregates was distinct from surface Ig.
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Citations
Cited by
Human lymphocyte subpopulations. Effect of corticosteroids.
Yu, D. T., Clements, P. J., Paulus, H. E., Peter, J. B., Levy, J., & Barnett, E. V. (1974) · Journal of Clinical Investigation · doi:10.1172/jci107591 · Cited by 310
C1q: A fresh look upon an old molecule
Thielens, N. M., Tedesco, F., Bohlson, S. S., Gaboriaud, C., & Tenner, A. J. (2017) · Molecular Immunology · doi:10.1016/j.molimm.2017.05.025 · Cited by 237
“…cells, Macrophages, DCs, PMNs Tetramer; neck + Clectin domain gC1q ICAM-3, gC1qR Regulation of DC differentiation (trimolecular complex with gC1qR) in the early 1970s (Dickler and Kunkel, 1972) and subsequently demonstrated for most cells of the peripheral blood under various conditions, as well…”
Background
Metadata
- Authors
- Dickler, H. B., & Kunkel, H. G.
- Venue
- The Journal of Experimental Medicine
- Publisher
- Rockefeller University Press
- Published
- 1972-07-01
- Volume
- 136
- Issue
- 1
- Pages
- 191-196
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W2090007108
- Cited by
- 672
- References
- 0
- FWCI
- 28.01
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: INTERACTION OF AGGREGATED γ-GLOBULIN WITH B LYMPHOCYTES. https://app.cochat.ai/papers/10.1084/jem.136.1.191
- The paper
- Dickler, H. B., & Kunkel, H. G. (1972). INTERACTION OF AGGREGATED γ-GLOBULIN WITH B LYMPHOCYTES. The Journal of Experimental Medicine. https://doi.org/10.1084/jem.136.1.191
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.