The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Human lymphocyte subpopulations. Effect of corticosteroids.
Open accessAbstract
Normal subjects given 60 mg of prednisone orally at 8:00 a.m. developed a transient lymphopenia at 2:00 p.m. To define the populations of lymphocytes affected the number and type of lymphocytes in the peripheral blood were assayed. "Late" and "early" spontaneous sheep red blood cell rosettes were used as markers for thymus-derived (T) lymphocytes and one of its subpopulations, respectively. Receptors for aggregated gammaglobulin and complement identified bursal-equivalent or bone marrow-derived (B) lymphocytes and one of its subpopulations, respectively. 6 h after administration of 60 mg of prednisone, the blood samples showed a decrease in proportion of T cells from 69.2 +/- 2.1% to 55.9 +/- 2.8% (average +/- SE) and an increase in B-cell proportion from 21.3 +/- 2.0% to 44.8 +/- 4.1%. The changes of "early" rosettes and complement receptor lymphocytes also paralleled these. In all cases the absolute numbers of T cells and of B cells were decreased by prednisone. The density gradient distribution of the lymphocytes did not change after prednisone. These data indicate that both T and B lymphocytes are affected by the prednisone but that the T cell lymphopenia was more pronounced. The lymphopenia might reflect either sequestration in the marrow and/or transient arrest of recirculation.
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Citations
Cites
Corticosteroids and Lymphoid Cells
Claman, H. N. (1972) · New England Journal of Medicine · doi:10.1056/nejm197208242870806 · Cited by 1,016
INTERACTION OF AGGREGATED γ-GLOBULIN WITH B LYMPHOCYTES
Dickler, H. B., & Kunkel, H. G. (1972) · The Journal of Experimental Medicine · doi:10.1084/jem.136.1.191 · Cited by 672
Human lymphocyte-sheep erythrocyte rosette formation: Some characteristics of the interation
Bentwich, Z., Douglas, S. D., Siegal, F. P., & Kunkel, H. G. (1973) · Clinical Immunology and Immunopathology · doi:10.1016/0090-1229(73)90007-x · Cited by 313
Thymus-Derived Lymphocytes Sequestered in the Bone Marrow of Hydrocortisone-Treated Mice
Cohen, J. J. (1972) · The Journal of Immunology · doi:10.4049/jimmunol.108.3.841 · Cited by 172
Nelson, D. H., Sandberg, A. A., Palmer, J. G., & Tyler, F. H. (1952) · Journal of Clinical Investigation · doi:10.1172/jci102671 · Cited by 119
Claman, H. N., Moorhead, J. W., & Benner, W. H. (1971) · PubMed · Cited by 113
Inhibition of lymphocyte recirculation by stress and corticotropin
Spry, C. J. F. (1972) · Cellular Immunology · doi:10.1016/0008-8749(72)90007-x · Cited by 63
The effect of alternate-day prednisone on the white blood count in children with chronic asthma
CHAI, H., & Gilbert, A. P. (1973) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(73)80001-6 · Cited by 25
Cited by
Glucocorticosteroid Therapy: Mechanisms of Action and Clinical Considerations
FAUCI, A. S., DALE, D. C., & BALOW, J. E. (1976) · Annals of Internal Medicine · doi:10.7326/0003-4819-84-3-304 · Cited by 1,044
McEwen, B. S., Biron, C. A., Brunson, K. W., Bulloch, K., Chambers, W. H., Dhabhar, F. S., Goldfarb, R. H., Kitson, R. P., Miller, A. H., Spencer, R. L., et al. (1997) · Brain Research Reviews · doi:10.1016/s0165-0173(96)00012-4 · Cited by 837
McKay, L. I., & Cidlowski, J. A. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.4.0375 · Cited by 805
Effects of Corticosteroid Therapy on Human Monocyte Function
Rinehart, J. J., Sagone, A. L., Balcerzak, S. P., Ackerman, G. A., & LoBuglio, A. F. (1975) · New England Journal of Medicine · doi:10.1056/nejm197501302920504 · Cited by 264
Effects of selective type I and II adrenal steroid agonists on immune cell distribution.
Miller, A. H., Spencer, R. L., hassett, J., Kim, C., Rhee, R., Ciurea, D., Dhabhar, F., McEwen, B., & Stein, M. (1994) · Endocrinology · doi:10.1210/endo.135.5.7956914 · Cited by 90
Metadata
- Authors
- Yu, D. T., Clements, P. J., Paulus, H. E., Peter, J. B., Levy, J., & Barnett, E. V.
- Venue
- Journal of Clinical Investigation
- Published
- 1974-02-01
- Volume
- 53
- Issue
- 2
- Pages
- 565-571
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W2032949137
- Cited by
- 310
- References
- 8
- FWCI
- 11.23
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Yu, D. T., Clements, P. J., Paulus, H. E., Peter, J. B., Levy, J., & Barnett, E. V. (1974). Human lymphocyte subpopulations. Effect of corticosteroids. Journal of Clinical Investigation. https://doi.org/10.1172/jci107591
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
