The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Plasma fibronectin enhances phagocytosis of opsonized particles by human peripheral blood monocytes.
Open accessAbstract
We have investigated the effect of plasma fibronectin (Fn) on binding and phagocytosis of sheep erythrocytes (E) by human peripheral blood monocytes. Unopsonized E were not phagocytosed in the absence or presence of Fn, but Fn enhanced the phagocytosis of E bearing IgG. Sheep erythrocytes sensitized with IgM and C3b were ingested only when monocytes were exposed to Fn. The Fn enhancement of phagocytosis occurred for both fluid-phase and glass-adherent monocytes. Experiments in which Fn was washed out before mixing monocytes with opsonized E demonstrated that the Fn effect occurred because of interaction with the monocytes and not the opsonized particles. Chromatography of the Fn on Biogel A 1.5m showed that the phagocytosis-enhancing activity exactly co-chromatographed with the Fn protein. Fn did not increase the number of monocyte membrane receptors for the Fc fragment of monomeric IgG. We conclude that Fn enhances monocyte phagocytosis, not by binding to particles as a conventional opsonin, but by stimulating monocytes to ingest already opsonized particles more avidly.
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Cites
Vuento, M., & Vaheri, A. (1979) · Biochemical Journal · doi:10.1042/bj1830331 · Cited by 545
The role of membrane receptors for C3b and C3d in phagocytosis.
Ehlenberger, A. G., & Nussenzweig, V (1977) · The Journal of experimental medicine · doi:10.1084/jem.145.2.357 · Cited by 534
Large scale isolation of functionally active components of the human complement system.
Hammer, C. H., Wirtz, G. H., Renfer, L., Gresham, H. D., & Tack, B. F. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)69557-8 · Cited by 437
Receptors for cold-insoluble globulin (plasma fibronectin) on human monocytes.
Bevilacqua, M. P., Amrani, D., Mosesson, M. W., & Bianco, C. (1981) · The Journal of experimental medicine · doi:10.1084/jem.153.1.42 · Cited by 312
Fibronectin fragment(s) are chemotactic for human peripheral blood monocytes.
Norris, D. A., Clark, R. A. F., Swigart, L. M., Huff, J. C., Weston, W. L., & Howell, S. E. (1982) · The Journal of Immunology · doi:10.4049/jimmunol.129.4.1612 · Cited by 288
Czop, J. K., Kadish, J. L., & Austen, K. F. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.6.3649 · Cited by 86
Griffin, F. M., & Mullinax, P. J. (1981) · The Journal of Experimental Medicine · doi:10.1084/jem.154.2.291 · Cited by 78
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Mechanisms of phagocytosis in macrophages
Aderem, A., & Underhill, D. M. (1999) · Annual Review of Immunology · doi:10.1146/annurev.immunol.17.1.593 · Cited by 2,854
Phagocytosis of Microbes: Complexity in Action
Underhill, D. M., & Ozinsky, A. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.103001.114744 · Cited by 1,124
Phagocytosis and the actin cytoskeleton
May, R. C., & Machesky, L. M. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.6.1061 · Cited by 715
Biomaterial biocompatibility and the macrophage
Anderson, J. M., & Miller, K. M. (1984) · Biomaterials · doi:10.1016/0142-9612(84)90060-7 · Cited by 403
THORENS, B. (1987) · Cell · doi:10.1016/0092-8674(87)90245-5 · Cited by 353
Metadata
- Authors
- Pommier, C. G., Inada, S., Fries, L. F., Takahashi, T., Frank, M. M., & Brown, E. J.
- Venue
- The Journal of experimental medicine
- Publisher
- Rockefeller University Press
- Published
- 1983-06-01
- Volume
- 157
- Issue
- 6
- Pages
- 1844-1854
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W2005284378
- Cited by
- 275
- References
- 8
- FWCI
- 8.11
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Pommier, C. G., Inada, S., Fries, L. F., Takahashi, T., Frank, M. M., & Brown, E. J. (1983). Plasma fibronectin enhances phagocytosis of opsonized particles by human peripheral blood monocytes. The Journal of experimental medicine. https://doi.org/10.1084/jem.157.6.1844
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
