PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection

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Items 301–400 of 889

1. Functional impairment of HIV-specific CD8+ T cells precedes aborted spontaneous control of viremia
   David R. Collins, Jonathan M. Urbach, Zachary J. Racenet, Umar Arshad, Karen A. Power, Ruchi M. Newman, Geetha Mylvaganam, Ngoc L. Ly, Xiaodong Lian, Anna Rull et al. · 2021 · Immunity
2. Unique T-Cell Populations Define Immune-Inflamed Hepatocellular Carcinoma
   Daniela Di Blasi, Tuyana Boldanova, Lucia Mori, Luigi Terracciano, Markus Hermann Heim, Gennaro De Libero · 2019 · Cellular and Molecular Gastroenterology and Hepatology
3. Therapeutic Vaccination Expands and Improves the Function of the HIV-Specific Memory T-Cell Repertoire
   Joseph Paul Casazza, Kathryn A. Bowman, Selorm Adzaku, Emily C. Smith, Mary E. Enama, Robert T. Bailer, David A. Price, Emma Gostick D, Ingelise J. Gordon, David R. Ambrozak et al. · 2013 · The Journal of Infectious Diseases
4. Immunological correlates of protection from HIV infection and disease
   Jonathan Luke Heeney, Stanley Alan Plotkin · 2006 · Nature Immunology
5. A fully human IgG1 anti‐PD‐L1 MAb in an in vitro assay enhances antigen‐specific T‐cell responses
   Italia Grenga, Renee Nicole Donahue, Lauren Marissa Lepone, Jacob Richards, Jeffrey Schlom · 2016 · Clinical & Translational Immunology
6. A heterogeneous hierarchy of co-regulatory receptors regulates exhaustion of HCV-specific CD8 T cells in patients with chronic hepatitis C
   Solomon Owusu Sekyere, Pothakamuri Venkata Suneetha, Anke R.M. Kraft, Shihong Zhang, Julia Dietz, Christoph Sarrazin, Michael Peter Manns, Verena Schlaphoff, Markus Cornberg, Heiner H. Wedemeyer · 2014 · Journal of Hepatology
7. Vaccine-induced myeloid cell population dampens protective immunity to SIV
   Yongjun Sui, Alison E. Hogg, Yichuan Wang, Blake F. Frey, Huifeng Yu, Zheng Xia, David J. Venzon, Katherine M. McKinnon, Jeremy V Smedley, Mercy Gathuka et al. · 2014 · Journal of Clinical Investigation
8. Re-defining T-Cell Exhaustion: Subset, Function, and Regulation
   Se Jin Im, Sang‐Jun Ha · 2020 · Immune Network
9. The micro RNA ‐9/ B ‐lymphocyte‐induced maturation protein‐1/ IL ‐2 axis is differentially regulated in progressive HIV infection
   Nabila Seddiki, Chansavath Phetsouphanh, Sanjay Swaminathan, Yin Xu, Sudha Rao, Jasmine Li, Elissa L. Sutcliffe, Gareth S Denyer, Robert James Finlayson, Linda Gelgor et al. · 2012 · European Journal of Immunology
10. A potential role for the PD1/PD-L1 pathway in the neuroinflammation of Alzheimer's disease
    Marina Saresella, Elena Calabrese, Ivana Marventano, Federica Piancone, Andrea Valer Gatti, Elisabetta Farina, Margherita Alberoni, Mario Clerici · 2011 · Neurobiology of Aging
11. A naturally occurring CD8+CD122+ T-cell subset as a memory-like Treg family
    Shanshan Li, Qingfeng Xie, Yuqun Zeng, Chuan Zou, Xusheng Liu, Shouhai Wu, Haixia Deng, Yang Xu, X.C. Li, Zhenhua Dai · 2014 · Cellular and Molecular Immunology
12. Dynamics of T-Cell Responses and Memory T Cells during Primary Simian Immunodeficiency Virus Infection in Cynomolgus Macaques
    Ingrid Karlsson, Benoît Malleret, Patricia Brochard, Benoît Delache, Julien Calvo, Roger Le Grand, Bruno Vaslin · 2007 · Journal of Virology
13. Immunometabolic Regulations Mediated by Coinhibitory Receptors and Their Impact on T Cell Immune Responses
    Nikolaos Patsoukis, Jessica D. Weaver, Laura Strauss, Christoph Herbel, Pankaj Seth, Vassiliki A. Boussiotis · 2017 · Frontiers in Immunology
14. Dynamic decrease in PD-1 expression correlates with HBV-specific memory CD8 T-cell development in acute self-limited hepatitis B patients
    Zheng Zhang, Bo Jin, Ji‐Yuan Zhang, Bin Xu, Huifen Wang, Ming Shi, E. John Wherry, George K.K. Lau, Fusheng Wang · 2009 · Journal of Hepatology
15. Programmed death-1 receptor negatively regulates LPS-mediated IL-12 production and differentiation of murine macrophage RAW264.7 cells
    Hae-Yun Cho, Eun-Kyoung Choi, Soo-Woon Lee, Keun‐Ok Jung, Su‐Kil Seo, Il‐Whan Choi, Sae-Gwang Park, Inhak Choi, Soo-Woong Lee · 2009 · Immunology Letters
16. Proliferation Capacity and Cytotoxic Activity Are Mediated by Functionally and Phenotypically Distinct Virus-Specific CD8 T Cells Defined by Interleukin-7Rα (CD127) and Perforin Expression
    Cristina Cellerai, Matthieu Perreau, Virginie Rozot, Felicitas Bellutti Enders, Giuseppe Pantaleo, Alexandre Harari · 2010 · Journal of Virology
17. Loss of DNAM‐1 contributes to CD8+ T‐cell exhaustion in chronic HIV‐1 infection
    Marina Cella, Rachel M. Presti, William Vermi, Kerry J. Lavender, Emma L. Turnbull, Christina Ochsenbauer‐Jambor, John C. Kappes, Guido Ferrari, Lisa Kessels, Ian G. Williams et al. · 2010 · European Journal of Immunology
18. FoxP3+CD25+CD8+T-Cell Induction during Primary Simian Immunodeficiency Virus Infection in Cynomolgus Macaques Correlates with Low CD4+T-Cell Activation and High Viral Load
    Ingrid Karlsson, Benoît Malleret, Patricia Brochard, Benoît Delache, Julien Calvo, Roger Le Grand, Bruno Vaslin · 2007 · Journal of Virology
19. Preclinical evaluation of the efficacy, pharmacokinetics and immunogenicity of JS-001, a programmed cell death protein-1 (PD-1) monoclonal antibody
    Jie Fu, Fang Wang, Lihou Dong, Jing Zhang, Cheng-lian Deng, Xueli Wang, Xin-yao Xie, Jing Zhang, Ruoxian Deng, Libo Zhang et al. · 2017 · Acta Pharmacologica Sinica
20. Strategies to Eliminate HBV Infection
    Rama Kapoor, Shyam Kottilil · 2014 · Future Virology
21. PD-1-Dependent Mechanisms Maintain Peripheral Tolerance of Donor-Reactive CD8+ T Cells to Transplanted Tissue
    Brent H. Koehn, Mandy L. Ford, Ivana R. Ferrer, Keshawna Borom, Shivaprakash Gangappa, Allan D. Kirk, Christian P. Larsen · 2008 · The Journal of Immunology
22. Hepatitis C virus–specific CD4+ T cell phenotype and function in different infection outcomes
    Diana Y. Chen, David Wolski, Jasneet Aneja, Lyndon Matsubara, Brandon Robilotti, Garrett D. Hauck, Paulo Sérgio Fonseca de Sousa, Sonu Subudhi, Carlos Augusto Fernandes, Ruben C. Hoogeveen et al. · 2020 · Journal of Clinical Investigation
23. Myeloid-Derived Suppressor Cells in Murine Retrovirus-Induced AIDS Inhibit T- and B-Cell ResponsesIn VitroThat Are Used To Define the Immunodeficiency
    Kathy A. Green, W. James Cook, William R. Green · 2012 · Journal of Virology
24. CD8+CD122+ T-Cells: A Newly Emerging Regulator with Central Memory Cell Phenotypes
    Junfeng Liu, Dacan Chen, Golay D. Nie, Zhenhua Dai · 2015 · Frontiers in Immunology
25. Intrahepatic PD-1/PD-L1 Up-regulation Closely Correlates with Inflammation and Virus Replication in Patients with Chronic HBV Infection
    Zhunyi Xie, Yongwen Chen, Songtao Zhao, Zhiqing Yang, Xiaohong Yao, Sheng Jie Guo, Chengying Yang, Lei Fei, Xing-Guang ZENG, Bing Ni et al. · 2009 · Immunological Investigations
26. The depths of PD-1 function within the tumor microenvironment beyond CD8+ T cells
    Stephanie Laba, Grace Mallett, Shoba Amarnath · 2021 · Seminars in Cancer Biology
27. Cytotoxicity and Secretion of Gamma Interferon Are Carried Out by Distinct CD8 T Cells duringMycobacterium tuberculosisInfection
    Thorbjorg Einarsdottir, Euan Lockhart, JoAnne L. Flynn · 2009 · Infection and Immunity
28. Clinical development of monoclonal antibody-based drugs in HIV and HCV diseases
    Michela Flego, Alessandro Ascione, Maurizio Cianfriglia, Stefano Vella · 2013 · BMC Medicine
29. Programmed death (PD)-1 molecule and its ligand PD-L1 distribution among memory CD4 and CD8 T cell subsets in human immunodeficiency virus-1-infected individuals
    Guglielmo Rosignoli, Chang Hyun Lim, Mark Bower, F Gotch, Nesrina Imami · 2009 · Clinical & Experimental Immunology
30. B and T Lymphocyte Attenuator Tempers Early Infection Immunity
    Sun, Yonglian, Brown, Nicholas K, Ruddy, Matthew J, Miller, Mendy L, Lee, Youjin, Wang, Yang, Murphy, Kenneth M, Pfeffer, Klaus, Chen, Lieping, Kaye, Jonathan et al. · 2009 · The Journal of Immunology
31. Variable Patterns of Programmed Death-1 Expression on Fully Functional Memory T Cells after Spontaneous Resolution of Hepatitis C Virus Infection
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32. Exhaustion of the CD8+ T Cell Compartment in Patients with Mutations in Phosphoinositide 3-Kinase Delta
    M. Wentink, Yvonne M. Mueller, V. Dalm, G. Driessen, P. V. van Hagen, J. V. van Montfrans, M. van der Burg, P. Katsikis · 2018 · Frontiers in Immunology
33. Interleukin-15 but Not Interleukin-7 Abrogates Vaccine-Induced Decrease in Virus Level in Simian Immunodeficiency Virusmac251-Infected Macaques
    Anna Hryniewicz, David A. Price, Marcin Moniuszko, Adriano Boasso, Yvette Edghill Spano, Sadie M. West, David J. Venzon, Monica Vaccari, Wen-Po Tsai, Elżbieta Anna Tryniszewska et al. · 2007 · The Journal of Immunology
34. Programmed Cell Death 1-Directed Immunotherapy for Enhancing T-Cell Function
    Koichi Araki, Ben Youngblood, Rafi Ahmed · 2013 · Cold Spring Harbor Symposia on Quantitative Biology
35. Programmed death-1 as a factor in immune exhaustion and activation in HIV infection
    DE Kaufmann, Bruce D. Walker · 2008 · Current Opinion in HIV and AIDS
36. HIV-1 Infection Is Associated with Depletion and Functional Impairment of Mycobacterium tuberculosis–Specific CD4 T Cells in Individuals with Latent Tuberculosis Infection
    Cheryl L. Day, Deborah Ann Abrahams, Levelle D. Harris, Michele van Rooyen, Lynnett Stone, Marwou de Kock, Willem Albert Hanekom · 2017 · The Journal of Immunology
37. A LAG-3–Specific Agonist Antibody for the Treatment of T Cell–Induced Autoimmune Diseases
    Mathieu Angin, Chrystelle Brignone, Frédéric Triebel · 2020 · The Journal of Immunology
38. Expression of PD-1 and Tim-3 markers of T-cell exhaustion is associated with CD4 dynamics during the course of untreated and treated HIV infection
    Norma Ibón Rallón, Marcial García, Javier García‐Samaniego, Alfonso Cabello, Beatriz Álvarez, Clara Restrepo, Sara Nistal, Miguel Górgolas, Jose Miguel Benito · 2018 · PLoS ONE
39. Negative Regulation of Type I IFN Expression by OASL1 Permits Chronic Viral Infection and CD8+ T-Cell Exhaustion
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40. PD1 as a common candidate susceptibility gene of subacute sclerosing panencephalitis
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41. Cellular and molecular mechanisms of memory T-cell survival
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42. Elite athletes on regular training show more pronounced induction of vaccine-specific T-cells and antibodies after tetravalent influenza vaccination than controls
    Alexandra Ledo, David Schub, Clemens Ziller, Martin Enders, Tanja Stenger, Barbara Christine Gärtner, Tina Schmidt, Tim Meyer, Martina Sester · 2019 · Brain Behavior and Immunity
43. Up-Regulation of Programmed Death-1 Expression on Beryllium-Specific CD4+ T Cells in Chronic Beryllium Disease
    Brent E. Palmer, Douglas G. Mack, Arlan D. Martin, May M. Gillespie, Margaret M. Mroz, Lisa A. Maier, Andrew P. Fontenot · 2008 · The Journal of Immunology
44. New Insights into the Role of PD-1 and Its Ligands in Allergic Disease
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45. HIV-Induced Changes in T Cell Signaling Pathways
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46. Immunity to Cytomegalovirus in Early Life
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47. Therapeutic Blockade of Transforming Growth Factor Beta Fails To Promote Clearance of a Persistent Viral Infection
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48. Increased B7-H1 Expression on Dendritic Cells Correlates with Programmed Death 1 Expression on T Cells in Simian Immunodeficiency Virus-Infected Macaques and May Contribute to T Cell Dysfunction and Disease Progression
    Huanbin Xu, Xiaolei Wang, Bapi Pahar, Terri Moroney‐Rasmussen, Xavier A. Alvarez, Andrew A. Lackner, Ronald S. Veazey · 2010 · The Journal of Immunology
49. Phenotype, effector function, and tissue localization of PD-1-expressing human follicular helper T cell subsets
    Chuanwu Wang, Peter Hillsamer, Chang H. Kim · 2011 · BMC Immunology
50. Functional Unresponsiveness and Replicative Senescence of Myeloid Leukemia Antigen–specific CD8+ T Cells After Allogeneic Stem Cell Transplantation
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51. The quest for a T cell-based immune correlate of protection against HIV: a story of trials and errors
    Richard A. Koup, Barney S. Graham, Daniel C. Douek · 2010 · Nature reviews. Immunology
52. Diminished Viral Control during Simian Immunodeficiency Virus Infection Is Associated with Aberrant PD-1hi CD4 T Cell Enrichment in the Lymphoid Follicles of the Rectal Mucosa
    Geetha Mylvaganam, Vijayakumar Velu, Jung‐Joo Hong, Shanmugalakshmi Sadagopal, Suefen Kwa, Rahul Basu, Benton Lawson, Francois J. Villinger, Rama Rao Amara · 2014 · The Journal of Immunology
53. Inhibitory TCR Coreceptor PD-1 Is a Sensitive Indicator of Low-Level Replication of SIV and HIV-1
    Nadine C. Salisch, DE Kaufmann, Amany S. Awad, Roger Keith Reeves, Daniel P. Tighe, Yuan Li, Michael Piatak, Jeffrey D. Lifson, David T. Evans, Florencia Pereyra et al. · 2009 · The Journal of Immunology
54. Programmed death-1 receptor suppresses γ-IFN producing NKT cells in human tuberculosis
    Amar Ranjan Singh, Aparajit Ballav Dey, Anant Mohan, Dipendra Kumar Mitra · 2014 · Tuberculosis
55. Regulation of T‐cell migration and effector functions: insights from in vivo imaging studies
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56. Tim-3 identifies exhausted follicular helper T cells in breast cancer patients
    Shiguang Zhu, Jun Lin, Guangdong Qiao, Xingmiao Wang, Yanping Xu · 2016 · Immunobiology
57. Therapeutic Vaccines for the Treatment of HIV
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58. Exhausted T cells hijacking the cancer-immunity cycle: Assets and liabilities
    Anna E. Brunell, Riitta Lahesmaa, Anu K Autio, Anil K. Thotakura · 2023 · Frontiers in Immunology
59. Current topics in HIV-1 pathogenesis: The emergence of deregulated immuno-metabolism in HIV-infected subjects
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60. HIV-Specific CD8+T Cells from Elite Controllers Are Primed for Survival
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61. Down‐modulation of programmed death 1 alters regulatory T cells and promotes experimental autoimmune encephalomyelitis
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62. Activation-induced Cell Death Drives Profound Lung CD4+ T-Cell Depletion in HIV-associated Chronic Obstructive Pulmonary Disease
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63. The role of PD‐1 in regulation of macrophage apoptosis and its subversion by Leishmania donovani
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64. Immune Checkpoints as the Immune System Regulators and Potential Biomarkers in HIV-1 Infection
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65. Regulation of PD-1 in T cells for cancer immunotherapy
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66. Increased PD-1 and decreased CD28 expression in chronic hepatitis B patients with advanced hepatocellular carcinoma
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67. The Role of Interleukin-6 in the Expression of PD-1 and PDL-1 on Central Nervous System Cells following Infection with Theiler's Murine Encephalomyelitis Virus
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68. Follicular helper T cell exhaustion induced by PD-L1 expression in hepatocellular carcinoma results in impaired cytokine expression and B cell help, and is associated with advanced tumor stages.
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69. Phenotype and function of protective T cell immune responses in HIV
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70. Limited Immunogenicity of HIV CD8+ T-Cell Epitopes in Acute Clade C Virus Infection
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71. Reduced Tim-3 Expression on Human T-lymphotropic Virus Type I (HTLV-I) Tax-specific Cytotoxic T Lymphocytes in HTLV-I Infection
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72. Upregulation of Immune Checkpoint Molecules, PD-1 and LAG-3, on CD4+ and CD8+ T Cells after Gastric Cancer Surgery.
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73. Pathogenic virus-specific T cells cause disease during treatment with the calcineurin inhibitor FK506: implications for transplantation
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74. An altered cytotoxic program of CD8+ T-cells in HIV-infected patients despite HAART-induced viral suppression
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75. CD57+ Memory T Cells Proliferate In Vivo
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76. Activation drives PD‐1 expression during vaccine‐specific proliferation and following lentiviral infection in macaques
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77. Reversal of functional defects in highly differentiated young and old CD8 T cells by PDL blockade
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78. New therapeutic vaccination strategies for the treatment of chronic hepatitis B
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79. Natural Suppression of Human Immunodeficiency Virus Type 1 Replication Is Mediated by Transitional Memory CD8+T Cells
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80. Expansion of CD8+ T cells lacking Sema4D/CD100 during HIV-1 infection identifies a subset of T cells with decreased functional capacity
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81. Exploiting the Interplay between Innate and Adaptive Immunity to Improve Immunotherapeutic Strategies for Epstein-Barr-Virus-Driven Disorders
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82. Upregulation of TIM-3 and PD-1 on CD4+ and CD8+ T Cells Associated with Dysfunction of Cell-Mediated Immunity after Colorectal Cancer Operation.
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83. The PD-1 pathway as a therapeutic target to overcome immune escape mechanisms in cancer
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84. Innate and Adaptive Immune Responses Both Contribute to Pathological CD4 T Cell Activation in HIV-1 Infected Ugandans
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85. Crystal clear: visualizing the intervention mechanism of the PD-1/PD-L1 interaction by two cancer therapeutic monoclonal antibodies
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86. Influenza-Specific T Cells from Older People Are Enriched in the Late Effector Subset and Their Presence Inversely Correlates with Vaccine Response
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87. Elevated Expression of CD160 and 2B4 Defines a Cytolytic HIV-Specific CD8+T-Cell Population in Elite Controllers
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88. The Antiviral CD8+ T Cell Response Is Differentially Dependent on CD4+ T Cell Help Over the Course of Persistent Infection
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89. The immunological synapse: the gateway to the HIV reservoir
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90. Highly competent, non-exhausted CD8+ T cells continue to tightly control pathogen load throughout chronic Trypanosoma cruzi infection
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91. Phosphorylation of PD-1-Y248 is a marker of PD-1-mediated inhibitory function in human T cells
    Kankana Bardhan, Halil‐Ibrahim Aksoylar, Thibault Le Bourgeois, Laura Strauss, Jessica D. Weaver, Bethany Delcuze, Alain Charest, Nikolaos Patsoukis, Vassiliki A. Boussiotis · 2019 · Scientific Reports
92. Role of the PD‐1/PD‐L1 Signaling in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis: Recent Insights and Future Directions
    Yan Mi, Jinming Han, Jie Zhu, Tao Jin · 2021 · Molecular Neurobiology
93. Increased PD‐L1 expression and PD‐L1/CD86 ratio on dendritic cells were associated with impaired dendritic cells function in HCV infection
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94. Host CCL3L1 Gene Copy Number in Relation to HIV-1-Specific CD4+ and CD8+ T-Cell Responses and Viral Load in South African Women
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95. Control of Virus-Specific CD8+T-Cell Exhaustion and Immune-Mediated Pathology by E3 Ubiquitin Ligase Cbl-b during Chronic Viral Infection
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96. HIV-Mediated Phosphatidylinositol 3-Kinase/Serine–Threonine Kinase Activation in APCs Leads to Programmed Death-1 Ligand Upregulation and Suppression of HIV-Specific CD8 T Cells
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97. Targeting the PD-1/PD-L1 Signaling Pathway for Cancer Therapy: Focus on Biomarkers
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98. Functional role of mucosal-associated invariant T cells in HIV infection
    Alireza Saeidi, Rada Ellegård, Yean Kong Yong, Hong Yien Tan, Vijayakumar Velu, James E. Ussher, Marie Larsson, Esaki Muthu Shankar · 2016 · Journal of Leukocyte Biology
99. Therapeutic vaccines and immunological intervention in HIV infection
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100. B Cell Responses to HIV Antigen Are a Potent Correlate of Viremia in HIV-1 Infection and Improve with PD-1 Blockade
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