Molecular Analysis of ATP-sensitive K Channel Gating and Implications for Channel Inhibition by ATP

Cited by (154)

Items 101–154 of 154

1. Localization of the ATP/Phosphatidylinositol 4,5 Diphosphate-binding Site to a 39-Amino Acid Region of the Carboxyl Terminus of the ATP-regulated K+ Channel Kir1.1*
   K. Dong, L. Tang, G. MacGregor, S. Hebert · 2002 · Journal of Biological Chemistry
2. A Kir6.2 mutation causing severe functional effects in vitro produces neonatal diabetes without the expected neurological complications
   Paolo Tammaro, Sarah Elizabeth Flanagan, Brittany Zadek, S. Srinivasan, Helen Woodhead, Shihab Ahmed Hameed, I Klimeś, Andrew Tym Hattersley, Sian Ellard, Frances Mary Ashcroft · 2008 · Diabetologia
3. Regulation of Cloned Atp-Sensitive K Channels by Adenine Nucleotides and Sulfonylureas
   S. John, J. Weiss, B. Ribalet · 2001 · The Journal of General Physiology
4. Blocker protection by short spermine analogs: refined mapping of the spermine binding site in a Kir channel.
   H. Kurata, Karthikeyan Diraviyam, L. Marton, C. Nichols · 2008 · Biophysical Journal
5. ATP‐sensitive K+ channels: regulation of bursting by the sulphonylurea receptor, PIP2 and regions of Kir6.2
   B. Ribalet, S. John, Lai-Hua Xie, James N. Weiss · 2006 · Journal of Physiology
6. Characterisation of new KATP-channel mutations associated with congenital hyperinsulinism in the Finnish population
   F. Reimann, H. Huopio, M. Dabrowski, P. Proks, F. Gribble, M. Laakso, T. Otonkoski, F. M. Ashcroft · 2003 · Diabetologia
7. Analysis of the differential modulation of sulphonylurea block of β‐cell and cardiac ATP‐sensitive K+ (KATP) channels by Mg‐nucleotides
   F. Reimann, M. Dabrowski, Phillippa Jones, F. Gribble, F. M. Ashcroft · 2003 · Journal of Physiology
8. DEND Mutation in Kir6.2 (KCNJ11) Reveals a Flexible N-Terminal Region Critical for ATP-Sensing of the KATP Channel
   Joseph C. Koster, Harley T. Kurata, Decha Enkvetchakul, Colin G. Nichols · 2008 · Biophysical Journal
9. Sulfonylurea Therapy in Two Korean Patients with Insulin-treated Neonatal Diabetes due to Heterozygous Mutations of the KCNJ11 Gene Encoding Kir6.2
   Min Sun Kim, Sun Young Kim, Gu-Hwan Kim, Han Wook Yoo, Dong Whan Lee, Dae‐Yeol Lee · 2007 · Journal of Korean Medical Science
10. Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A KATP channels: A mechanistic study
    Proks, Peter, de Wet, Heidi, Ashcroft, Frances M. · 2014 · Journal of General Physiology
11. Nucleotide inhibition of the pancreatic ATP-sensitive K+ channel explored with patch-clamp fluorometry
    S. Usher, F. Ashcroft, Michael C. Puljung · 2019 · bioRxiv
12. Glibenclamide unresponsiveness in a Brazilian child with permanent neonatal diabetes mellitus and DEND syndrome due to a C166Y mutation in KCNJ11 (Kir6.2) gene
    Thaís Della Manna, Claudilene Battistim, Vanessa Radonsky, Roberta Diaz Savoldelli, Durval Damiani, Fernando Kok, Ewan R. Pearson, Sian Ellard, Andrew Tym Hattersley, André Fernandes Reis · 2008 · Arquivos Brasileiros de Endocrinologia & Metabologia
13. Control of Kir channel gating by cytoplasmic domain interface interactions
    William F. Borschel, Shizhen Wang, Sun-Joo Lee, Colin G. Nichols · 2017 · The Journal of General Physiology
14. Gating of the ATP-sensitive K+ channel by a pore-lining phenylalanine residue.
    Asheebo Rojas, Jian-Ping Wu, Run-Ping Wang, Chun Jiang · 2007 · Biochimica et Biophysica Acta
15. Phosphatidic acid stimulates cardiac KATP channels like phosphatidylinositols, but with novel gating kinetics.
    Zheng Fan, Lizhi Gao, Wenxia Wang · 2003 · American Journal of Physiology - Cell Physiology
16. Evaluating inositol phospholipid interactions with inward rectifier potassium channels and characterising their role in disease
    Tanadet Pipatpolkai, Robin Adam Corey, Peter Proks, Frances Mary Ashcroft, Phillip J. Stansfeld · 2020 · Communications Chemistry
17. Molecular Mechanisms of Chloroquine Inhibition of Heterologously Expressed Kir6.2/SUR2A Channels
    Daniela Ponce-Balbuena, Aldo A. Rodríguez-Menchaca, A. Lopez-Izquierdo, Tania Ferrer, H. Kurata, Colin G. Nichols, J. Sánchez-Chapula · 2012 · Molecular Pharmacology
18. Interaction between mutations in the slide helix of Kir6.2 associated with neonatal diabetes and neurological symptoms
    Roope Männikkö, Craig Jefferies, Sarah Elizabeth Flanagan, Andrew Tym Hattersley, Sian Ellard, Frances Mary Ashcroft · 2009 · Human Molecular Genetics
19. Functional analysis of two Kir6.2 ( KCNJ11 ) mutations, K170T and E322K, causing neonatal diabetes
    Andrei I. Tarasov, Christophe A. J. Girard, Brian Larkin, Paolo Tammaro, Sarah Elizabeth Flanagan, Sian Ellard, F M Ashcroft · 2007 · Diabetes Obesity and Metabolism
20. Carvedilol blocks cardiac KATP and KG but not IK1 channels by acting at the bundle-crossing regions.
    J. Kikuta, M. Ishii, Kentaro Kishimoto, Y. Kurachi · 2006 · European Journal of Pharmacology
21. Analysis of Two KCNJ11 Neonatal Diabetes Mutations, V59G and V59A, and the Analogous KCNJ8 I60G Substitution
    Marcus Winkler, Rebekka Lutz, Ulrich Ruß, Ulrich Quast, Joseph Bryan · 2009 · Journal of Biological Chemistry
22. Protons Activate Homomeric Kir6.2 Channels by Selective Suppression of the Long and Intermediate Closures
    Jianping Wu, Haoxing Xu, Zhenjiang Yang, Y. Wang, Jinzhe Mao, Chun Ling Jiang · 2002 · The Journal of Membrane Biology
23. Interaction of stilbene disulphonates with cloned KATP channels
    P. Proks, P. Jones, F. Ashcroft · 2001 · British Journal of Pharmacology
24. Expression, purification, and evidence for the interaction of the two nucleotide-binding folds of the sulphonylurea receptor.
    E. Hough, Lindsey A. Mair, W. Mackenzie, A. Sivaprasadarao · 2002 · Biochemical and Biophysical Research Communications - BBRC
25. The dynamic interplay of PIP2 and ATP in the regulation of the KATP channel
    Tanadet Pipatpolkai, S. Usher, Natascia Vedovato, F. Ashcroft, P. Stansfeld · 2021 · bioRxiv
26. Decomposition of Slide Helix Contributions to ATP-dependent Inhibition of Kir6.2 Channels
    Jenny B.W. Li, Xinyang Huang, Roger Shen Zhang, Robin Y. Kim, Runying Y. Yang, Harley T. Kurata · 2013 · Journal of Biological Chemistry
27. Subunit-Stoichiometric Evidence for Kir6.2 Channel Gating, ATP Binding, and Binding-Gating Coupling
    Runping Wang, Xiaoli Zhang, Ningren Cui, Jianping Wu, Hailan Piao, Xueren Wang, Junda Su, Chun Ling Jiang · 2007 · Molecular Pharmacology
28. Regulation of gating by negative charges in the cytoplasmic pore in the Kir2.1 channel
    Lai-Hua Xie, S. John, B. Ribalet, James N. Weiss · 2004 · Journal of Physiology
29. Verapamil, a Ca2+ Entry Blocker, Targets the Pore-Forming Subunit of Cardiac Type KATP Channel (Kir6.2)
    Tomonori Ninomiya, M. Takano, T. Haruna, Yutaka Kono, M. Horie · 2003 · Journal of Cardiovascular Pharmacology
30. A Threonine Residue (Thr71) at the Intracellular End of the M1 Helix Plays a Critical Role in the Gating of Kir6.2 Channels by Intracellular ATP and Protons
    N. Cui, Jianping Wu, Hao-Xing Xu, Run-Ping Wang, Asheebo Rojas, H. Piao, Jinzhe Mao, Latifat Abdulkadir, Lilly Li, Chun Jiang · 2003 · Journal of Membrane Biology
31. Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATP Channel Mutations in Intact Cells
    Jian Hua Gao, Conor McClenaghan, Kenneth A. Matreyek, Dorothy Katherine Grange, Colin G. Nichols · 2023 · Journal of Pharmacology and Experimental Therapeutics
32. Ligand-dependent Linkage of the ATP Site to Inhibition Gate Closure in the KATP Channel
    Lehong Li, Xuehui Geng, Michael J. Yonkunas, An-Jey A. Su, Erik Densmore, Pei Song Tang, Peter F. Drain · 2005 · The Journal of General Physiology
33. Cytoplasmic Vestibule of the Weak Inward Rectifier Kir6.2 Potassium Channel*
    Yijun Cui, Wenxia Wang, Zheng Fan · 2002 · Journal of Biological Chemistry
34. A universally conserved residue in the SUR1 subunit of the KATP channel is essential for translating nucleotide binding at SUR1 into channel opening
    Heidi de Wet, Kenju Shimomura, Jussi Aittoniemi, Nawaz Ahmad, Mathilde Lafond, Mark S.P. Sansom, Frances Mary Ashcroft · 2012 · The Journal of Physiology
35. The Kir6.2‐F333I mutation differentially modulates KATP channels composed of SUR1 or SUR2 subunits
    Paolo Tammaro, Frances Mary Ashcroft · 2007 · The Journal of Physiology
36. Base of pore loop is important for rectification, activation, permeation, and block of Kir3.1/Kir3.4.
    Samy M. Y. Makary, T. Claydon, K. Dibb, M. Boyett · 2006 · Biophysical Journal
37. Disopyramide block of K(ATP) channels is mediated by the pore-forming subunit.
    B. Zunkler, S. Kühne, Ingo Rustenbeck, T. Ott, Alfred G. Hildebrandt · 2000 · Life Science
38. A Conserved Residue Cluster That Governs Kinetics of ATP-dependent Gating of Kir6.2 Potassium Channels
    Roger Shen Zhang, Jordan D. Wright, Stephan Alexander Pless, John-Jose Nuñez, Robin Y. Kim, Jenny B.W. Li, Runying Y. Yang, Christopher A. Ahern, Harley T. Kurata · 2015 · Journal of Biological Chemistry
39. Determinant Role of Membrane Helices in KATP Channel Gating
    Run-Ping Wang, Asheebo Rojas, Jianping Wu, H. Piao, C. Y. Adams, Hao-Xing Xu, Yun Shi, Ying Wang, Chun Jiang · 2005 · Journal of Membrane Biology
40. Critical protein domains and amino acid residues for gating the KIR6.2 channel by intracellular ATP
    Jian-Ping Wu, H. Piao, Asheebo Rojas, Run-Ping Wang, Ying Wang, N. Cui, Yun-Bo Shi, Fu-Xue Chen, Chun Jiang · 2004 · Journal of Cellular Physiology
41. Mechanism of Kir6.2 channel inhibition by sulfhydryl modification: pore block or allosteric gating?
    Yijun Cui, Zheng Fan · 2002 · Journal of Physiology
42. Kir6.2 Channel Gating by Intracellular Protons: Subunit Stoichiometry for Ligand Binding and Channel Gating
    Run-Ping Wang, Jun-Da Su, Xiao-Li Zhang, Yun Shi, N. Cui, Vivian A. Onyebuchi, Chun Jiang · 2006 · Journal of Membrane Biology
43. Computational Identification of Novel Kir6 Channel Inhibitors
    Xing-Yu Chen, A. Garon, M. Wieder, M. Houtman, Eva-Maria Zangerl-Plessl, T. Langer, M. V. D. van der Heyden, Anna Stary-Weinzinger · 2019 · bioRxiv
44. Effects of ZD0947, a novel and potent ATP-sensitive K+ channel opener, on smooth muscle-type ATP-sensitive K+ channels.
    Keisuke Mori, Y. Yamashita, N. Teramoto · 2016 · European Journal of Pharmacology
45. Oxidation Driven Reversal of PIP2-dependent Gating in GIRK2 Channels
    Sun-Joo Lee, S. Maeda, Jian Gao, C. Nichols · 2023 · Function
46. From Bacteria to Human: Biophysical Studies of Inward Rectifying Potassium Channels
    Wayland Wing-Lun Cheng · 2012 · Open Scholarship Institutional Repository (Washington University in St. Louis)
47. Inward Rectifying Potassium Channels
    H. Kurata, C. Nichols · 2009
48. Assessment of Gymnema sylvestre in association with Magnesium and Vitamin D3 on glycemic control in Type 2 Diabetes Mellitus: A prospective, open-label, single-arm study with possible mechanistic insights
    N. Nema, Smitha Sarojam, K. K, Chandu Devanpally, Varghese Jacob · 2026 · Clinical Traditional Medicine and Pharmacology
49. From Prokaryotes to Eukaryotes: Molecular Modeling and Simulation Studies of Ion Channels
    P. Biggin, A. Grottesi, M. Sansom · 2005
50. Evolution of Potassium Channel Proteins
    W. Gallin, A. N. Spencer · 2001
51. Structure and function of cardiac ATP-sensitive K+channels
    M. Yamada, Y. Kurachi · 1999
52. Functional Consequences of Cantu Syndrome Associated Mutations in the ATP Sensitive Potassium Channel
    Paige Cooper · 2015 · Open Scholarship Institutional Repository (Washington University in St. Louis)
53. ATP-Sensitive Potassium Channels in Health and Disease
    Peter Proks, Rebecca H. Clark · 2014 · Springer eBooks
54. Molecular Biology of Inward Rectifier and ATP-Sensitive Potassium Channels
    Show‐Ling Shyng, Anatoli N. Lopatin, Colin G. Nichols · 2001 · Springer eBooks