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Cited by 304

The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.

Vancomycin-Intermediate and -Resistant Staphylococcus aureus: What the Infectious Disease Specialist Needs to Know

Weinstein, R. A., Fridkin, S. K.·2001·Clinical Infectious Diseases

Abstract

Ever since the first strain of Staphylococcus aureus with reduced susceptibility to vancomycin and teicoplanin was reported from Japan, there has been a lot of confusion regarding the laboratory and clinical approach to patients with infections due to S. aureus with reduced susceptibility to vancomycin. To date, 6 clinical infections with vancomycin-intermediate S. aureus (VISA) have been reported in the United States. Intermediate resistance appears to develop from preexisting strains of methicillin-resistant S. aureus in the presence of vancomycin, and all but 1 infection occurred in patients with exposure to dialysis for renal insufficiency. Detection of VISA is difficult in the laboratory, and special inquiries about susceptibility testing methods may be needed. These VISA-infected patients had underlying illnesses, and their infections did not appear to respond well to conventional treatment. Prevention strategies have been outlined. Without continued vigilance in enforcing infection-control measures, improved use of antimicrobials, and coordination of efforts among public health authorities, increasing levels of vancomycin resistance in S. aureus are likely to be encountered.

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Metadata

Authors
Weinstein, R. A., & Fridkin, S. K.
Venue
Clinical Infectious Diseases
Published
2001-01-01
Volume
32
Issue
1
Pages
108-115
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
OpenAlex
W2168207172
Cited by
304
References
30
FWCI
23.09
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Vancomycin-Intermediate and -Resistant Staphylococcus aureus: What the Infectious Disease Specialist Needs to Know. https://app.cochat.ai/papers/10.1086/317542
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Weinstein, R. A., & Fridkin, S. K. (2001). Vancomycin-Intermediate and -Resistant Staphylococcus aureus: What the Infectious Disease Specialist Needs to Know. Clinical Infectious Diseases. https://doi.org/10.1086/317542

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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