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Cited by 637

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Antiretroviral Therapy Adherence and Viral Suppression in HIV‐Infected Drug Users: Comparison of Self‐Report and Electronic Monitoring

Open access
Arnsten, Julia H., Demas, Penelope A., Farzadegan, Homayoon, Grant, Richard W., Gourevitch, Marc N., Chang, Chee‐Jen, Buono, Donna, Eckholdt, Haftan, Howard, Andrea A., Schoenbaum, Ellie E.·2001·Clinical Infectious Diseases

Abstract

To compare electronically monitored (MEMS) with self-reported adherence in drug users, including the impact of adherence on HIV load, we conducted a 6-month observational study of 67 antiretroviral-experienced current and former drug users. Adherence (percentage of doses taken as prescribed) was calculated for both the day and the week preceding each of 6 research visits. Mean self-reported 1-day adherence was 79% (median, 86%), and mean self-reported 1-week adherence was 78% (median, 85%). Mean MEMS 1-day adherence was 57% (median, 52%), and mean MEMS 1-week adherence was 53% (median, 49%). One-day and 1-week estimates were highly correlated (r>.8 for both measures). Both self-reported and MEMS adherence were correlated with concurrent HIV load (r=.43-.60), but the likelihood of achieving virologic suppression was greater if MEMS adherence was high than if self-reported adherence was high. We conclude that self-reported adherence is higher than MEMS adherence, but a strong relationship exists between both measures and virus load. However, electronic monitoring is more sensitive than self-report for the detection of nonadherence and should be used in adherence intervention studies.

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Metadata

Authors
Arnsten, J. H., Demas, P. A., Farzadegan, H., Grant, R. W., Gourevitch, M. N., Chang, C., Buono, D., Eckholdt, H., Howard, A. A., & Schoenbaum, E. E.
Venue
Clinical Infectious Diseases
Published
2001-10-15
Volume
33
Issue
8
Pages
1417-1423
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
OpenAlex
W2121731508
Cited by
637
References
2
FWCI
18.80
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Antiretroviral Therapy Adherence and Viral Suppression in HIV‐Infected Drug Users: Comparison of Self‐Report and Electronic Monitoring. https://app.cochat.ai/papers/10.1086/323201
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Arnsten, J. H., Demas, P. A., Farzadegan, H., Grant, R. W., Gourevitch, M. N., Chang, C., Buono, D., Eckholdt, H., Howard, A. A., & Schoenbaum, E. E. (2001). Antiretroviral Therapy Adherence and Viral Suppression in HIV‐Infected Drug Users: Comparison of Self‐Report and Electronic Monitoring. Clinical Infectious Diseases. https://doi.org/10.1086/323201

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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