The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Barriers to Antiretroviral Adherence for Patients Living with HIV Infection and AIDS in Botswana
Abstract
BACKGROUND: Botswana has the highest rate of HIV infection in the world, estimated at 36% among the population aged 15-49 years. To improve antiretroviral (ARV) treatment delivery, we conducted a cross-sectional study of the social, cultural, and structural determinants of treatment adherence. METHODS: We used both qualitative and quantitative research methodologies, including questionnaires and interviews with patients receiving ARV treatment and their health care providers to elicit principal barriers to adherence. Patient report and provider estimate of adherence (>/=95% doses) were the primary outcomes. RESULTS: One hundred nine patients and 60 health care providers were interviewed between January and July 2000; 54% of patients were adherent by self-report, while 56% were adherent by provider assessment. Observed agreement between patients and providers was 68%. Principal barriers to adherence included financial constraints (44%), stigma (15%), travel/migration (10%), and side effects (9%). On the basis of logistic regression, if cost were removed as a barrier, adherence is predicted to increase from 54% to 74%. CONCLUSIONS: ARV adherence rates in this study were comparable with those seen in developed countries. As elsewhere, health care providers in Botswana were often unable to identify which patients adhere to their ARV regimens. The cost of ARV therapy was the most significant barrier to adherence.
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Cited by
Stigma in the HIV/AIDS epidemic: a review of the literature and recommendations for the way forward
Mahajan, A. P., Sayles, J. N., Patel, V. A., Remien, R. H., Sawires, S. R., Ortiz, D. J., Szekeres, G., & Coates, T. J. (2008) · AIDS · doi:10.1097/01.aids.0000327438.13291.62 · Cited by 1,404
Impact of HIV‐related stigma on treatment adherence: systematic review and meta‐synthesis
Katz, I. T., Ryu, A. E., Onuegbu, A. G., Psaros, C., Weiser, S. D., Bangsberg, D. R., & Tsai, A. C. (2013) · Journal of the International AIDS Society · doi:10.7448/ias.16.3.18640 · Cited by 1,126
Self-citationAdherence to Antiretroviral Therapy in Sub-Saharan Africa and North America: A Meta-analysis
Mills, E. J., Nachega, J. B., Buchan, I., Orbinski, J., Attaran, A., Singh, S., Rachlis, B., Wu, P., Cooper, C., Thabane, L., et al. (2006) · JAMA · doi:10.1001/jama.296.6.679 · Cited by 899
Self-citationMills, E. J., Nachega, J. B., Bangsberg, D. R., Singh, S., Rachlis, B., Wu, P., Wilson, K., Buchan, I., Gill, C. J., & Cooper, C. (2006) · PLoS Medicine · doi:10.1371/journal.pmed.0030438 · Cited by 818
Self-citationVanable, P. A., Carey, M. P., Blair, D. C., & Littlewood, R. A. (2006) · AIDS and Behavior · doi:10.1007/s10461-006-9099-1 · Cited by 619
Metadata
- Authors
- Weiser, S., Wolfe, W., Bangsberg, D., Thior, I., Gilbert, P., Makhema, J., Kebaabetswe, P., Dickenson, D., Mompati, K., Essex, M., & Marlink, R.
- Venue
- JAIDS Journal of Acquired Immune Deficiency Syndromes
- Published
- 2003-11
- Volume
- 34
- Issue
- 3
- Pages
- 281-288
- ISSN
- 1525-4135 (ISSN-L)
- OpenAlex
- W1981655325
- Cited by
- 473
- References
- 1
- FWCI
- 7.75
- Type
- journal article
- Language
- en
- Open access
- closed
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- Weiser, S., Wolfe, W., Bangsberg, D., Thior, I., Gilbert, P., Makhema, J., Kebaabetswe, P., Dickenson, D., Mompati, K., Essex, M., & Marlink, R. (2003). Barriers to Antiretroviral Adherence for Patients Living with HIV Infection and AIDS in Botswana. JAIDS Journal of Acquired Immune Deficiency Syndromes. https://doi.org/10.1097/00126334-200311010-00004
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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