The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
Primaquine Therapy for Malaria
Abstract
Primaquine is the only available drug for preventing relapse of malaria, and confusion surrounds its use. This review examines the wide range of clinical applications of primaquine described in the medical literature between 1946 and 2004. The risk of relapse of Plasmodium vivax malaria without primaquine therapy ranged from 5% to 80% or more, depending largely upon geographic location. Supervision of therapy profoundly impacts the risk of relapse, and almost all reports of malaria resistant to primaquine are associated with lack of such supervision. We nonetheless suspect that there is widespread resistance to the standard course of primaquine therapy, which is 15 mg primaquine base daily for 14 days. Clinical evidence confirms that a course of 15 mg daily for just 5 days, a regimen widely used in areas where malaria is endemic, has no discernible efficacy. This review supports a recommendation for a regimen of 0.5 mg/kg primaquine daily for 14 days, on the basis of superior efficacy and good tolerability and safety in nonpregnant persons without glucose-6-phosphate dehydrogenase deficiency.
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Cites
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The Journal of Laboratory and Clinical Medicine
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Indian Journal of Medical Research
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British Journal of Pharmacology
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PLASMODIUM VIVAX RESISTANCE TO CHLOROQUINE?
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Drug-Induced Methaemoglobinaemia Treatment Issues
Coleman, M. D., & Coleman, N. A. (1996) · Drug Safety · doi:10.2165/00002018-199614060-00005 · Cited by 275
Resistance to Chloroquine by Plasmodium vivax in Irian Jaya, Indonesia
Baird, J. K., Basri, H., Purnomo, Bangs, M. J., Subianto, B., Patchen, L. C., & Hoffman, S. L. (1991) · The American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.1991.44.547 · Cited by 232
Self-citationCompliance With Topical Timolol Treatment
Kass, M. A., Gordon, M., Morley, R. E., Meltzer, D. W., & Goldberg, J. J. (1987) · American Journal of Ophthalmology · doi:10.1016/s0002-9394(14)74225-4 · Cited by 212
Cited by
Evidence and Implications of Mortality Associated with Acute Plasmodium vivax Malaria
Baird, J. K. (2013) · Clinical Microbiology Reviews · doi:10.1128/cmr.00074-12 · Cited by 398
Self-citationEffectiveness of Antimalarial Drugs
Baird, J. K. (2005) · New England Journal of Medicine · doi:10.1056/nejmra043207 · Cited by 375
Self-citationRobinson, L. J., Wampfler, R., Betuela, I., Karl, S., White, M. T., Li Wai Suen, C. S. N., Hofmann, N. E., Kinboro, B., Waltmann, A., Brewster, J., et al. (2015) · PLOS Medicine · doi:10.1371/journal.pmed.1001891 · Cited by 276
Malaria in pregnancy in the Asia-Pacific region
Rijken, M. J., McGready, R., Boel, M. E., Poespoprodjo, R., Singh, N., Syafruddin, D., Rogerson, S., & Nosten, F. (2012) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(11)70315-2 · Cited by 181
Treating Severe Malaria in Pregnancy: A Review of the Evidence
Kovacs, S. D., Rijken, M. J., & Stergachis, A. (2015) · Drug Safety · doi:10.1007/s40264-014-0261-9 · Cited by 66
Metadata
- Authors
- Baird, J. K., & Hoffman, S. L.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2004-11-01
- Volume
- 39
- Issue
- 9
- Pages
- 1336-1345
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2158149195
- Cited by
- 435
- References
- 42
- FWCI
- 14.04
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
