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Less Than 95% Adherence to Nonnucleoside Reverse‐Transcriptase Inhibitor Therapy Can Lead to Viral Suppression
Abstract
For antiretroviral therapy, the 95% adherence "threshold" is based on nucloside-exposed patients who are receiving partially suppressive, unboosted protease inhibitor regimens. Using unannounced pill counts and electronic medication monitoring, viral suppression is common with a 54%-100% mean adherence level to nonnucleoside reverse-transcriptase-inhibitor regimens. Although perfect adherence is an important goal, viral suppression is possible with moderate adherence to potent regimens.
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Cited by
Behavioural strategies to reduce HIV transmission: how to make them work better
Coates, T. J., Richter, L., & Caceres, C. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60886-7 · Cited by 760
Azar, M. M., Springer, S. A., Meyer, J. P., & Altice, F. L. (2010) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2010.06.014 · Cited by 394
Finitsis, D. J., Pellowski, J. A., & Johnson, B. T. (2014) · PLoS ONE · doi:10.1371/journal.pone.0088166 · Cited by 355
Bärnighausen, T., Chaiyachati, K., Chimbindi, N., Peoples, A., Haberer, J., & Newell, M.-L. (2011) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(11)70181-5 · Cited by 246
Preventing HIV Antiretroviral Resistance through Better Monitoring of Treatment Adherence
Bangsberg, D. R. (2008) · The Journal of Infectious Diseases · doi:10.1086/533415 · Cited by 183
Self-citation
Metadata
- Authors
- Bangsberg, D. R.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-10
- Volume
- 43
- Issue
- 7
- Pages
- 939-941
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W1973708179
- Cited by
- 534
- References
- 0
- FWCI
- 21.03
- Type
- journal article
- Language
- en
- Open access
- closed
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- Bangsberg, D. R. (2006). Less Than 95% Adherence to Nonnucleoside Reverse‐Transcriptase Inhibitor Therapy Can Lead to Viral Suppression. Clinical Infectious Diseases. https://doi.org/10.1086/507526
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.