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Cited by 502

The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.

Relationship between Nasopharyngeal Colonization and the Development of Otitis Media in Children

Faden, Howard, Duffy, Linda, Wasielewski, Raymond, Wolf, Judy, Krystofik, Debra, Tung, Ying, Tonawanda/Williamsville Pediatrics·1997·The Journal of Infectious Diseases

Abstract

Streptococcus pneumoniae, nontypeable Haemophilus influenzae, and Moraxella catarrhalis are the predominant bacteria associated with otitis media. A cohort of 306 infants was followed from birth through 12 months to determine frequency and duration of colonization and risk of acute otitis media (AOM) and otitis media with effusion (OME). M. catarrhalis was the most common bacterium isolated. Infants colonized at < or = 3 months of age were at increased risk of AOM and OME. Early colonization with M. catarrhalis revealed the greatest risk (relative risk [RR] = 1.24), especially for OME (RR = 1.57). There was a strong relationship between the frequency of colonization and OM (r = .37, P < .001,) for each pathogen. Although S. pneumoniae, nontypeable H. influenzae, and M. catarrhalis are part of the normal nasopharyngeal flora during infancy, an increased rate of colonization may identify a subpopulation of children that is at increased risk of OM.

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Metadata

Authors
Faden, H., Duffy, L., Wasielewski, R., Wolf, J., Krystofik, D., Tung, Y., & Pediatrics, T.
Venue
The Journal of Infectious Diseases
Published
1997-06
Volume
175
Issue
6
Pages
1440-1445
ISSN
  • 0022-1899 (ISSN-L)
  • 1537-6613
OpenAlex
W2099409015
Cited by
502
References
20
FWCI
21.91
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Relationship between Nasopharyngeal Colonization and the Development of Otitis Media in Children. https://app.cochat.ai/papers/10.1086/516477
The paper
Faden, H., Duffy, L., Wasielewski, R., Wolf, J., Krystofik, D., Tung, Y., & Pediatrics, T. (1997). Relationship between Nasopharyngeal Colonization and the Development of Otitis Media in Children. The Journal of Infectious Diseases. https://doi.org/10.1086/516477

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.